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Endocrinology, Vol 100, 1039-1046, Copyright © 1977 by Endocrine Society

ARTICLES

Effect of thyrotropin on ornithine decarboxylase and of polyamines on RNA polymerase in the thyroid

SW Spaulding

Two major forms of RNA polymerase were partially purified from calf thyroid nuclei. Type I showed greatest activity in 30 mM(NH4)2SO4, transcribed native DNA best and was resistant to the inhibitor alpha- amanitin. Type II showed greatest activity in 100 mM(NH4)2SO4, transcribed denatured DNA template best and was sensitive to low concentrations of alpha-amanitin...




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Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1977 by The Endocrine Society