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Endocrinology, Vol 109, 316-318, Copyright © 1981 by Endocrine Society

ARTICLES

Decreased cell division of the uterine luminal epithelium of diabetic rats in response to 17 beta-estradiol

JL Kirkland, GN Barrett and GM Stancel

The uterine growth response to estradiol as determined by luminal epithelial cell division was measured in euglycemic and drug induced insulin deficient rats. The results demonstrated that uterine cell division in insulin deficient rats is depressed when compared to euglycemic rats. Replacement of insulin by osmotic minipumps (Alza Corporation) in insulin deficient rats restored the level of luminal cell division to those observed in euglycemic rats.


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D. R. Garris and B. L. Garris
Diabetes (db/db) Mutation-Induced Ovarian Involution: Progressive Hypercytolipidemia
Experimental Biology and Medicine, October 1, 2003; 228(9): 1040 - 1050.
[Abstract] [Full Text] [PDF]


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