help button home button Endocrine Society Endocrinology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gibbs, F. P.
Right arrow Articles by Vriend, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gibbs, F. P.
Right arrow Articles by Vriend, J.
Right arrowPubmed/NCBI databases
*Compound via MeSH
*Substance via MeSH

Endocrinology, Vol 109, 1796-1798, Copyright © 1981 by Endocrine Society

ARTICLES

The half-life of melatonin elimination from rat plasma

FP Gibbs and J Vriend

Tritiated or unlabeled melatonin was infused intra-arterially into unanesthetized male Sprague-Dawley rats. Blood samples were collected from the jugular vein over the next two hours and the melatonin concentrations determined in the plasma by liquid scintillation counting or by RIA. Data from the tritiated melatonin experiments gave a half-life of 23 min, and data from the RIA experiments gave a half- life of 17 min.


This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
M. Naguib, A. H. Samarkandi, M. A. Moniem, E. E.-D. Mansour, A. A. Alshaer, H. A. Al-Ayyaf, A. Fadin, and S. W. Alharby
The Effects of Melatonin Premedication on Propofol and Thiopental Induction Dose-Response Curves: A Prospective, Randomized, Double-Blind Study
Anesth. Analg., December 1, 2006; 103(6): 1448 - 1452.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
B. Ozcelik, I.S. Serin, M. Basbug, S. Uludag, F. Narin, and M. Tayyar
Effect of melatonin in the prevention of post-operative adhesion formation in a rat uterine horn adhesion model
Hum. Reprod., August 1, 2003; 18(8): 1703 - 1706.
[Abstract] [Full Text] [PDF]

Home page
 Pharmacol. Rev.Home page
V. Simonneaux and C. Ribelayga
Generation of the Melatonin Endocrine Message in Mammals: A Review of the Complex Regulation of Melatonin Synthesis by Norepinephrine, Peptides, and Other Pineal Transmitters
Pharmacol. Rev., June 1, 2003; 55(2): 325 - 395.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol PatholHome page
G. S. Travlos, R. E. Wilson, J. A. Murrell, C. F. Chignell, and G. A. Boorman
The Effect of Short Intermittent Light Exposures on the Melatonin Circadian Rhythm and NMU-Induced Breast Cancer in Female F344/N Rats
Toxicol Pathol, January 1, 2001; 29(1): 126 - 136.
[Abstract] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
L. A. Zarazaga, B. Malpaux, D. Guillaume, L. Bodin, and P. Chemineau
Genetic variability in melatonin concentrations in ewes originates in its synthesis, not in its catabolism
Am J Physiol Endocrinol Metab, June 1, 1998; 274(6): E1086 - E1090.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1981 by The Endocrine Society