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Endocrinology, Vol 110, 297-298, Copyright © 1982 by Endocrine Society

ARTICLES

Thyroid hormone stimulation in vitro of red blood cell Ca2+-ATPase activity: interspecies variation

FB Davis, JH Kite Jr, PJ Davis and SD Blas

In vitro susceptibility to thyroid hormone stimulation of membrane- associated Ca2+-ATPase activity has been examined in red blood cells from rat, rabbit, dog, monkey, and man. Monkey and human red cell Ca2+- ATPase activities responded comparably to 10(-10)M T4 or T3. Basal and thyroid hormone-stimulated Ca2+-ATPase activity in rabbit erythrocytes was four-fold higher than in primate red cells. Rat and dog red cell Ca2+-ATPase did not respond to iodothyronines in vitro.


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