help button home button Endocrine Society Endocrinology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Clark, J. H.
Right arrow Articles by Markaverich, B. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Clark, J. H.
Right arrow Articles by Markaverich, B. M.

Endocrinology, Vol 113, 1167-1169, Copyright © 1983 by Endocrine Society

ARTICLES

An endogenous ligand for the triphenylethylene antiestrogen binding site

JH Clark, RC Winneker, SC Guthrie and BM Markaverich

We have isolated an endogenous ligand which acts as a competitive inhibitor of the binding of 3H-tamoxifen to triphenylethylene antiestrogen-binding sites (TABS) prepared from liver and from serum low density lipoproteins (LDL). This ligand is present in boiled ethanol extracts of rat liver and may represent an "endogenous antiestrogen". "Endogenous antiestrogen" is used here as an operational term, since it has not been shown that TABS are involved in the mechanism of action of the triphenylethylene antiestrogens.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1983 by The Endocrine Society