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Endocrinology, Vol 114, 1947-1949, Copyright © 1984 by Endocrine Society

ARTICLES

Prolactin mRNA exists in rat hypothalamus

BS Schachter, S Durgerian, RE Harlan, DW Pfaff and BD Shivers

Using radiolabeled DNA complementary to rat pituitary prolactin mRNA, we probed RNA gel blots from three rat tissues: pituitary, hypothalamus, and liver. Poly (A)-enriched RNA from male and female hypothalami contained a hybridizable RNA which was the same size as, though less abundant than, mature pituitary PRL mRNA. These results support the proposal that the rat brain synthesizes PRL.




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Copyright © 1984 by The Endocrine Society