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Endocrinology, Vol 115, 556-558, Copyright © 1984 by Endocrine Society

ARTICLES

Epidermal growth factor stimulates growth hormone secretion from superfused rat adenohypophyseal fragments

H Ikeda, T Mitsuhashi, K Kubota, N Kuzuya and H Uchimura

Epidermal growth factor (EGF) stimulated GH secretion from superfused rat adenohypophyseal fragments in a dose-related manner (8-50 ng/ml). Secretion of PRL or TSH was not affected by EGF at concentrations up to 50 ng/ml. These results indicate that EGF may be a specific secretagogue for GH in rats.


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