help button home button Endocrine Society Endocrinology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jump, D. B.
Right arrow Articles by Oppenheimer, J. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jump, D. B.
Right arrow Articles by Oppenheimer, J. H.

Endocrinology, Vol 118, 1892-1896, Copyright © 1986 by Endocrine Society

ARTICLES

Dissociation of hepatic messenger ribonucleic acidS14 levels and nuclear transcriptional rates in suckling rats

DB Jump, TY Tao, HC Towle and JH Oppenheimer

The messenger RNA (mRNA) coding for the rat hepatic protein spot 14(S14) (mol wt 17,000; pI 4.9) is rapidly responsive to T3 and carbohydrate administration in the adult animal. In 15-day-old suckling rats, the level of expression is 200-fold less than in 60-day-old chow- fed animals. However, the relative transcriptional activity of the S14 gene is only 30% higher in the 60-day-old rat than in the 15-day-old animal. Although T3 induces a 100-fold increase in mRNAS14 in 15-day- old animals, there was only a 17% increase in the S14 gene transcriptional activity. These results indicate that the hormonal and developmental regulation of the S14 gene in liver appears to be predominantly directed at the posttranscriptional level.


This article has been cited by other articles:


Home page
 J. Biol. Chem.Home page
D. Botolin and D. B. Jump
Selective Proteolytic Processing of Rat Hepatic Sterol Regulatory Element Binding Protein-1 (SREBP-1) and SREBP-2 During Postnatal Development
J. Biol. Chem., February 21, 2003; 278(9): 6959 - 6962.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D. B. Jump, M. V. Badin, and A. Thelen
The CCAAT Box Binding Factor, NF-Y, Is Required for Thyroid Hormone Regulation of Rat Liver S14 Gene Transcription
J. Biol. Chem., October 31, 1997; 272(44): 27778 - 27786.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1986 by The Endocrine Society