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Endocrinology, doi:10.1210/endo-122-2-563
Endocrinology Vol. 122, No. 2 563-566
Copyright © 1988 by the Endocrine Society.
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Virus-Induced Thyroiditis

JAVARAIAH SRINIVASAPPA, CARLO GARZELLI, TAKASHI ONODERA, USHARANJAN RAY and ABNER LOUIS NOTKINS

Laboratory of Oral Medicine, National Institute of Dental Research, National Institutes of Health Bethesda, Maryland 20892

Address requests for reprints to: Abner Louis Notkins, M.D., Laboratory of Oral Medicine, National Institute of Dental Research, National Institutes of Health, Building 30, Room 121, Bethesda, Maryland 20892.

Abstract

Mice infected with reovirus type 1 developed a mild thyroiditis characterized by focal destruction of acinar tissue, infiltration of inflammatory cells, and autoantibodies to thyroglobulin and microsomal antigens. Thyroid involvement appears to be part of a more generalized virus-induced polyendocrine disease. (Endocrinology 122: 563–566, 1988)

Received March 19, 1987.




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