help button home button Endocrine Society Endocrinology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kennedy, T. G.
Right arrow Articles by Vaughan, T. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kennedy, T. G.
Right arrow Articles by Vaughan, T. J.

Endocrinology, Vol 132, 1857-1859, Copyright © 1993 by Endocrine Society

ARTICLES

Expression of the genes for the epidermal growth factor receptor and its ligands in porcine corpora lutea

TG Kennedy, KD Brown and TJ Vaughan
Department of Biochemistry, AFRC Institute of Animal Physiology and Genetics Research, Babraham, Cambridge, UK.

Using reverse transcription-polymerase chain reaction (RT-PCR), transcripts for EGF receptor and for EGF, transforming growth factor- alpha (TGF alpha), amphiregulin (AR) and heparin binding-EGF (HB-EGF) were detected in porcine corpora lutea at day 4, 10 and 20 of the estrous cycle. No cycle-dependent changes were apparent in the expression of the receptor, AR or TGF alpha. In contrast, HB-EGF mRNA levels appeared highest on day 4 during luteal growth and development, whereas EGF mRNA levels appeared highest on day 20 when the corpora lutea undergo luteolysis. These results suggest that luteal function may be subject to regulation by members of the EGF family acting in an autocrine, paracrine or intracrine manner.


This article has been cited by other articles:


Home page
 J EndocrinolHome page
X. Chen, B. Zhou, J. Yan, B. Xu, P. Tai, J. Li, S. Peng, M. Zhang, and G. Xia
Epidermal growth factor receptor activation by protein kinase C is necessary for FSH-induced meiotic resumption in porcine cumulus-oocyte complexes
J. Endocrinol., May 1, 2008; 197(2): 409 - 419.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
Y. Akayama, S. Takekida, N. Ohara, H. Tateiwa, W. Chen, K. Nakabayashi, and T. Maruo
Gene expression and immunolocalization of heparin-binding epidermal growth factor-like growth factor and human epidermal growth factor receptors in human corpus luteum
Hum. Reprod., October 1, 2005; 20(10): 2708 - 2714.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
J. Wang, N. Ohara, S. Takekida, Q. Xu, and T. Maruo
Comparative effects of heparin-binding epidermal growth factor-like growth factor on the growth of cultured human uterine leiomyoma cells and myometrial cells
Hum. Reprod., June 1, 2005; 20(6): 1456 - 1465.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
S. M. Khan, R. H. Oliver, and J. Yeh
Epidermal Growth Factor Receptor Inhibition by Tyrphostin 51 Induces Apoptosis in Luteinized Granulosa Cells
J. Clin. Endocrinol. Metab., January 1, 2005; 90(1): 469 - 473.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
S. K. Kuwada and X. Li
Integrin alpha 5/beta 1 Mediates Fibronectin-dependent Epithelial Cell Proliferation through Epidermal Growth Factor Receptor Activation
Mol. Biol. Cell, July 1, 2000; 11(7): 2485 - 2496.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1993 by The Endocrine Society