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Endocrinology Vol. 144, No. 6 2195-2200
Copyright © 2003 by The Endocrine Society

Minireview: Adiposity, Inflammation, and Atherogenesis

Christopher J. Lyon, Ronald E. Law and Willa A. Hsueh

Division of Endocrinology, Diabetes, and Hypertension, University of California at Los Angeles, Los Angeles, California 90095-7073

Address all correspondence and requests for reprints to: Willa A. Hsueh, M.D., Chief, Division of Endocrinology, Diabetes and Hypertension, University of California at Los Angeles, 900 Veteran Avenue, Suite 24-130, Los Angeles, California 90095-7073. E-mail: whsueh{at}mednet.ucla.edu.

Adipose tissue is a dynamic endocrine organ that secretes a number of factors that are increasingly recognized to contribute to systemic and vascular inflammation. Several of these factors, collectively referred to as adipokines, have now been shown regulate, directly or indirectly, a number of the processes that contribute to the development of atherosclerosis, including hypertension, endothelial dysfunction, insulin resistance, and vascular remodeling. Several adipokines are preferentially expressed in visceral adipose tissue, and the secretion of proinflammatory adipokines is elevated with increasing adiposity. Not surprisingly, approaches that reduce adipose tissue depots, including surgical fat removal, exercise, and reduced caloric intake, improve proinflammatory adipokine levels and reduce the severity of their resultant pathologies. Systemic adipokine levels can also be favorably altered by treatment with several of the existing drug classes used to treat insulin resistance, hypertension, and hypercholesterolemia. Greater understanding of adipokine regulation, however, should result in the design of improved treatment strategies to control disease states associated with increase adiposity, an important outcome in view of the growing worldwide epidemic of obesity.




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 Am. J. Clin. Nutr.Home page
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Home page
 J. Nutr.Home page
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Home page
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Home page
 QJMHome page
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Home page
 J. Lipid Res.Home page
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Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet
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 The Diabetes EducatorHome page
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 DiabetesHome page
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[Abstract] [Full Text] [PDF]

Home page
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Home page
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Home page
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Home page
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[Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
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Home page
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Home page
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Home page
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Home page
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[Abstract] [Full Text] [PDF]

Home page
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Home page
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Home page
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Home page
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Home page
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[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
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Home page
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Home page
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J. Am. Coll. Cardiol., May 16, 2006; 47(10): 1919 - 1926.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
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[Abstract] [Full Text] [PDF]

Home page
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[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
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J. Clin. Endocrinol. Metab., March 1, 2006; 91(3): 1042 - 1047.
[Abstract] [Full Text] [PDF]

Home page
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[Abstract] [Full Text] [PDF]

Home page
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[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
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[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
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Arterioscler. Thromb. Vasc. Biol., October 1, 2005; 25(10): 2062 - 2068.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
T. Murakami, H. Takagi, K. Suzuma, I. Suzuma, H. Ohashi, D. Watanabe, T. Ojima, E. Suganami, M. Kurimoto, H. Kaneto, et al.
Angiopoietin-1 Attenuates H2O2-induced SEK1/JNK Phosphorylation through the Phosphatidylinositol 3-Kinase/Akt Pathway in Vascular Endothelial Cells
J. Biol. Chem., September 9, 2005; 280(36): 31841 - 31849.
[Abstract] [Full Text] [PDF]

Home page
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[Abstract] [Full Text] [PDF]

Home page
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[Abstract] [Full Text] [PDF]

Home page
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Exp Physiol, September 1, 2005; 90(5): 697 - 702.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
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Home page
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Home page
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[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
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Am J Physiol Endocrinol Metab, June 1, 2005; 288(6): E1236 - E1243.
[Abstract] [Full Text] [PDF]

Home page
 Circ. Res.Home page
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Adipocyte Signaling and Lipid Homeostasis: Sequelae of Insulin-Resistant Adipose Tissue
Circ. Res., May 27, 2005; 96(10): 1042 - 1052.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
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J. Clin. Endocrinol. Metab., May 1, 2005; 90(5): 2927 - 2931.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
A. Xu, M. C. Lam, K. W. Chan, Y. Wang, J. Zhang, R. L. C. Hoo, J. Y. Xu, B. Chen, W.-S. Chow, A. W. K. Tso, et al.
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice
PNAS, April 26, 2005; 102(17): 6086 - 6091.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
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Production and Release of Macrophage Migration Inhibitory Factor from Human Adipocytes
Endocrinology, March 1, 2005; 146(3): 1006 - 1011.
[Abstract] [Full Text] [PDF]

Home page
 GutHome page
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Cytokines and the pathogenesis of non-alcoholic steatohepatitis
Gut, February 1, 2005; 54(2): 303 - 306.
[Full Text] [PDF]

Home page
 J. Lipid Res.Home page
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Impact of adiponectin gene polymorphisms on plasma lipoprotein and adiponectin concentrations of viscerally obese men
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[Abstract] [Full Text] [PDF]

Home page
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Interaction of Fish Oil and Conjugated Linoleic Acid in Affecting Hepatic Activity of Lipogenic Enzymes and Gene Expression in Liver and Adipose Tissue
Diabetes, February 1, 2005; 54(2): 412 - 423.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
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[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
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Palmitate-Induced Interleukin-6 Expression in Human Coronary Artery Endothelial Cells
Diabetes, December 1, 2004; 53(12): 3209 - 3216.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
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Induction of Adiponectin in Skeletal Muscle by Inflammatory Cytokines: in Vivo and in Vitro Studies
Endocrinology, December 1, 2004; 145(12): 5589 - 5597.
[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
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Low-Grade Inflammation and Microalbuminuria in Hypertension
Arterioscler. Thromb. Vasc. Biol., December 1, 2004; 24(12): 2414 - 2419.
[Abstract] [Full Text] [PDF]

Home page
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Circulation, November 23, 2004; 110(21): 3335 - 3340.
[Abstract] [Full Text] [PDF]

Home page
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Home page
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J. Lipid Res., September 1, 2004; 45(9): 1640 - 1648.
[Abstract] [Full Text] [PDF]

Home page
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Home page
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[Abstract] [Full Text] [PDF]

Home page
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Home page
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R S Vasan
Cardiac function and obesity
Heart, October 1, 2003; 89(10): 1127 - 1129.
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