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Endocrinology, doi:10.1210/endo-45-2-195
Endocrinology Vol. 45, No. 2 195-203
Copyright © 1949 by the Endocrine Society.
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THE EFFECT OF FOLLICLE STIMULATING HORMONE UPON OXYGEN CONSUMPTION OF CHICK OVARY SLICES1

OLGA NALBANDOV2 and ANDREW NALBANDOV

From the Department of Animal Science, University of Illinois URBANA

Abstract

THE GONADOTROPHIC FUNCTION of the pituitary gland has been the subject of many investigations by endocrinologists but these studies have for the most part been limited to measurement of anatomical and gross physiological responses of the gonads. There has been little work done to elucidate the mechanism by which the pituitary gonadotrophic hormones produce these effects. It is known that the follicle stimulating hormone (FSH) promotes the growth of ovarian follicles but it is not known how FSH affects cellular processes to bring about this end result. Therefore, it seems of interest to measure responses of ovarian tissue to FSH at the cellular level. Since FSH stimulates the ovary to greater activity measurable as increase in weight and rate of function one might expect an increased rate of respiration of ovarian tissue in response to the hormone. In this study the effect of FSH on the oxygen consumption of chick ovary slices has been measured.

Footnotes

1 This investigation was aided by grants from the University of Illinois Research Board and the U. S. Public Health Service—RG1819.

2 Postdoctoral Fellow of the University of Illinois Graduate School, Oct. 1947-June 1948; National Institutes of Health Postdoctoral Fellow, June 1948-June 1949.

Received May 31, 1949.






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Copyright © 1949 by The Endocrine Society