This Article Full Text (PDF) Submit a related Letter to the Editor Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints, Permissions and Rights Citing Articles Citing Articles via Google Scholar Google Scholar Articles by MOSIER, H. D. Search for Related Content PubMed PubMed Citation Articles by MOSIER, H. D.

THE DEVELOPMENT OF THE HYPOTHALAMO-NEUROHYPOPHYSIAL SECRETORY SYSTEM IN THE CHICK EMBRYO

Department of Pathology, Los Angeles Childrens Hospital, and the University of Southern California School of Medicine

Abstract

THE study of neurosecretion in vertebrates and invertebrates was greatly stimulated by Bargmann’s application of the chrom-hematoxylinphloxine stain of Gomori to the study of neurosecretory substance in the hypothalamo-neurohypophysial tract of the dog and cat. (Bargmann, 1949; Gomori, 1941). Since then this technique has been used with gratifying results in studies of neurosecretion in many animal species. One of the many problems investigated has been that of the ontogeny of the neurosecretory tracts of the hypothalamus.

Wingstrand (1954) has reported on the early formation of neurosecretory substance staining with Gomori’s stain in the chick embryo. He attempted to correlate the histological findings with bioassays for antidiuretic substance in the embryonic hypothalamus. Although there was physiological evidence of antidiuretic substance in the hypothalamus by the tenth day of incubation he found no histological evidence of neurosecretion until the 13th or 14th day.

Footnotes

¹ Present address: Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Maryland.

Received June 4, 1955.