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Change in Hair Color in Mice Induced by Injection of -MSH

Department of Animal Husbandry, University of California Davis, California 95616

This investigation was supported in part by USPHS Grant HD-00394.

Abstract

Mice of the black agouti C3H XAF₁ hybrid cross were injected with 5 X10⁵ U -MSH twice daily. Hair regrowing in shaved and plucked areas during the period of injections was black in color. The significance of this finding and its relationship to the circulating agent promoting hair darkening in animals bearing a previously described transplantable pituitary tumor are discussed. (Endocrinology 79: 1165, 1966)

Received June 13, 1966.

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