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Endocrinology, Vol 96, 129-134, Copyright © 1975 by Endocrine Society

ARTICLES

Episodic secretion of renin

RD Junnila, RH Travis and KB Brosnihan

Renin is secreted episodically in the absence of overt stimulation in the pentobarital-anesthetized, saline-loaded cat. Ninety min postlaparotomy, arterial and renal venous plasma renin concentrations (PRC) were determined at 15-min intervals for a 2 hr period. The pattern of renin secretion consisted of significant secretory peaks and periods in which little or no renin was secreted. In only a few instances could renin secretion be attributed to a preceding arterial blood pressure drop. The secretory episodes were also dissociated from flow.




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Copyright © 1975 by The Endocrine Society