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A Renin-like Activity in Pineal Gland and Hypophysis

Department of Physiology, Institute of Medicine and Pharmacy lasi, Romania

Abstract

The presence and distribution of renin-like activity in hypophysis, pineal gland and some neural tissues were studied in both normal and salt-loaded rats. The Boucher micromethod was used to detect enzymatic activity. In normal rats both the pituitary and pineal glands contained significantly higher values of renin-like activity than did the other tissues examined. In salt-loaded animals there was a significant decrease of the renin-like activity of the glandular tissue while in the other brain areas the activity increased. The results are discussed in terms of the possible physiological role of the central renin-angiotensin system in the regulation of fluid and electrolyte balance. (Endocrinology 96: 508, 1975)

Received May 20, 1974.

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