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Endocrinology, Vol 96, 508-510, Copyright © 1975 by Endocrine Society

ARTICLES

A renin-like activity in pineal gland and hypophysis

I Haulica, DD Branisteanu, V Rosca, A Stratone, V Berbeleu, G Balan and L Ionescu

The presence and distribution of renin-like activity in hypophysis, pineal gland and some neural tissues were studies in both normal and salt-loaded rats. The Boucher micromethod was used to detect enzymatic activity. In normal rats both the pituitary and pineal glands contained significantly higher values of renin-like activity than did the other tissues examined. In salt-loaded animals there was a significant decrease of the renin-like activity of the glandular tissue while in the other brain areas the activity increased. The results are discussed in terms of the possible physiological role of the central renin- angiotensin system in the regulation of fluid and electrolyte balance.


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V. Simonneaux and C. Ribelayga
Generation of the Melatonin Endocrine Message in Mammals: A Review of the Complex Regulation of Melatonin Synthesis by Norepinephrine, Peptides, and Other Pineal Transmitters
Pharmacol. Rev., June 1, 2003; 55(2): 325 - 395.
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