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Endocrinology, Vol 96, 523-525, Copyright © 1975 by Endocrine Society

ARTICLES

Absence of luteinizing hormone-releasing hormone (LH-RH) from catecholaminergic neurons

JS Kizer, A Arimura, AV Schally and MJ Brownstein

6-Hydroxy-dopamine was administered into the third ventricle of adult male rats. After 2 successive 250 mug doses of 6-OH-dopamine, the levels of norepinephrine and dopamine in the median eminence and arcuate nucleus fell to 15-20% of the control value. The amount of luteinizing hormone releasing hormone (LH-RH) in these same hypothalamic areas, however, was unchanged. It is concluded that LH-RH containing cells are distinct from catecholaminergic neurons.




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Copyright © 1975 by The Endocrine Society