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Endocrinology, Vol 96, 1595-1596, Copyright © 1975 by Endocrine Society


ARTICLES

Comparsion of hydroxyindole-O-methyltransferse levels in pineal glands of normal, blinded, and congenitally anophthalmic guiena pigs

BL Farriss and LD Botz

The level of pineal hydroxyindole-O-methyltransferase activity was measured in normal sighted, normal blinded, and congenitally anophthalmic guinea pigs at 1100-1200 and 2300-2400 h. Significant day- night differences were found in the normal sighted and normal blinded guinea pigs; however, the levels were markedly elevated in the normal blinded guinea pigs. The congenitally anophthalmic guinea pigs did not demonstrate a difference between day and night activities. Both the day and night levels of hydroxyindole-O-methyltransferase activities in the latter animals were slightly less than the low daytime levels for the normal, sighted guinea pigs.





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Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1975 by The Endocrine Society