This Article Full Text (PDF) Submit a related Letter to the Editor Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints, Permissions and Rights Citing Articles Citing Articles via Google Scholar Google Scholar Articles by BRIDGES, R. S. Articles by GOLDMAN, B. D. Search for Related Content PubMed PubMed Citation Articles by BRIDGES, R. S. Articles by GOLDMAN, B. D.

Ovarian Control of Prolactin Secretion During Late Pregnancy in the Rat¹

Department of Biobehavioral Sciences, The University of Connecticut Storrs, Connecticut 06268

Abstract

The involvement of the ovaries during late pregnancy in the rat upon serum prolactin was investigated. Ovariectomy on day 17 or day 21 of pregnancy prevented the dramatic rise of prolactin found in sham-ovariectomized animals between days 21 and 23 of pregnancy. While animals ovariectoinized on day 17 of pregnancy failed to carry viable fetuses beyond day 19 of pregnancy, rats ovariectomized on day 21 of pregnancy had viable pups in utero on day 23 of pregnancy. These data suggest that the rise in serum prolactin during late pregnancy is stimulated by ovarian factors. (Endocrinology 97: 496,1975)

Footnotes

¹ Aided in part by NIH Grant HD 05481 awarded to B. D. Goldman.

² Address reprint requests to Robert S. Bridges.

Received July 27, 1974.