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Endocrinology, Vol 98, 1475-1479, Copyright © 1976 by Endocrine Society

ARTICLES

Daily variation in concentration of plasma corticosteroid in hypophysectomized rats

AH Meier

A daily variation in the concentration of plasma corticosteroid hormone is present in hypophysectomized rats implanted with pellets of adrenocorticotropic hormone (ACTH) and thyroxine. Although ACTH is necessary to maintain a functional adrenal, and thyroxine is required to permit the expression of the plasma corticosteroid rhythm, a normal daily variation in plasma corticosteroid concentration does not appear to depend on the periodic release of pituitary hormones.


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