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FIG. 1. Islets cell morphology. Human islets were cultured for 1, 3, and 5 d in M199 medium, with 6 mM glucose, 10% FCS, and 0.1 mM diprotin-A and in the presence, or absence, of GLP-1 (10 nM, added every 12 h). Human islets on d 1, control (A) and GLP-1-treated islets (B); d 3, control (C) and GLP-1 treated (D); and d 5, control (E) and GLP-1 treated (F). Pictures are representative of islets morphology as observed by culturing human islets from three independent donors. Magnification, x20.
