Supplemental Data

Supplemental Data

Files in this Data Supplement:

• Supplemental Figure 1 - (A) Insulin concentrations of 1-month-old control (white bars) and Pax6m/+ mice (black bars) in the fasting or fed state (n=5). (B) Total GLP-1 level in 1-month-old control and Pax6m/+ mice (n=6). (C) Oral glucose tolerance test (OGTT) was performed on 8-month-old control and Pax6m/+ mice (n=5). (D) Serum GIP level released under glucose stimulation (n=6). Data are mean ± SE. *p < 0.05 (t-test) versus the corresponding value for control mice.
• Supplemental Figure 2 - Energy balance in control and Pax6m/+ mice. (A) Body temperature of 8-month-old control and Pax6m/+ mice in the fasting or fed state. (B) and (C) Energy in daily food and excreta from 8-month-old control and Pax6m/+ mice. (D) Energy expenditure and storage in 8-month-old control and Pax6m/+ mice. In (A)-(D), n=7-8 mice in each group. Data are mean ± SE. **p < 0.01 (t-test) versus the corresponding value for control mice.
• Supplemental Table 1 - Primers used in real-time RT PCR.