CANCER:

Zoltan Rekasi, Jozsef L. Varga, Andrew V. Schally, Gabor Halmos, Patricia Armatis, Kate Groot, and Tamas Czompoly

Antagonists of Growth Hormone-Releasing Hormone and Vasoactive Intestinal Peptide Inhibit Tumor Proliferation by Different Mechanisms: Evidence from in Vitro Studies on Human Prostatic and Pancreatic Cancers
Endocrinology 2000 141: 2120-2128, doi:10.1210/en.141.6.2120 [Abstract] [Full Text] [PDF]  

CRH-ACTH-POMC-ADRENAL:

Ji-Yao Li, Susan Finniss, Ying-Kui Yang, Qun Zeng, Song-Yi Qu, Greg Barsh, Chris Dickinson, and Ira Gantz

Agouti-Related Protein-Like Immunoreactivity: Characterization of Release from Hypothalamic Tissue and Presence in Serum
Endocrinology 2000 141: 1942-1950, doi:10.1210/en.141.6.1942 [Abstract] [Full Text] [PDF]  

Paola G. Andreis, Anna Markowska, Hunter C. Champion, Giuseppina Mazzocchi, Ludwik K. Malendowicz, and Gastone G. Nussdorfer

Adrenomedullin Enhances Cell Proliferation and Deoxyribonucleic Acid Synthesis in Rat Adrenal Zona Glomerulosa: Receptor Subtype Involved and Signaling Mechanism
Endocrinology 2000 141: 2098-2104, doi:10.1210/en.141.6.2098 [Abstract] [Full Text] [PDF]  

J. T. Ross, H. P. J. Bennett, S. James, and I. C. McMillen

Infusion of N-Proopiomelanocortin-(1–77) Increases Adrenal Weight and Messenger Ribonucleic Acid Levels of Cytochrome P₄₅₀ 17-Hydroxylase in the Sheep Fetus during Late Gestation
Endocrinology 2000 141: 2153-2158, doi:10.1210/en.141.6.2153 [Abstract] [Full Text] [PDF]  

C. Kwon Kim and Catherine L. Rivier

Nitric Oxide and Carbon Monoxide Have a Stimulatory Role in the Hypothalamic-Pituitary-Adrenal Response to Physico-Emotional Stressors in Rats
Endocrinology 2000 141: 2244-2253, doi:10.1210/en.141.6.2244 [Abstract] [Full Text] [PDF]  

GRH-SOMATOSTATIN-GH:

Ralf Nass, Joan Gilrain, Stacey Anderson, Bruce Gaylinn, Alan Dalkin, Richard Day, Mario Peruggia, and Michael O. Thorner

High Plasma Growth Hormone (GH) Levels Inhibit Expression of GH Secretagogue Receptor Messenger Ribonucleic Acid Levels in the Rat Pituitary
Endocrinology 2000 141: 2084-2089, doi:10.1210/en.141.6.2084 [Abstract] [Full Text] [PDF]  

Celia M. Pombo, Juan Zalvide, Bruce D. Gaylinn, and Carlos Diéguez

Growth Hormone-Releasing Hormone Stimulates Mitogen-Activated Protein Kinase
Endocrinology 2000 141: 2113-2119, doi:10.1210/en.141.6.2113 [Abstract] [Full Text] [PDF]  

Entela Bollano, Elmir Omerovic, Mohammad Bohlooly-Y, Vuk Kujacic, Basetti Madhu, Jan Tornell, Olle Isaksson, Bassam Soussi, Wolfgang Schulze, Michael L. X. Fu, Goran Matejka, Finn Waagstein, and Jorgen Isgaard

Impairment of Cardiac Function and Bioenergetics in Adult Transgenic Mice Overexpressing the Bovine Growth Hormone Gene
Endocrinology 2000 141: 2229-2235, doi:10.1210/en.141.6.2229 [Abstract] [Full Text] [PDF]  

GROWTH FACTORS-CYTOKINES-ONCOGENES:

Gunilla Dahlfors and Hans J. Arnqvist

Vascular Endothelial Growth Factor and Transforming Growth Factor-ß1 Regulate the Expression of Insulin-Like Growth Factor-Binding Protein-3, -4, and -5 in Large Vessel Endothelial Cells
Endocrinology 2000 141: 2062-2067, doi:10.1210/en.141.6.2062 [Abstract] [Full Text] [PDF]  

Pierre B. Saadeh, Babak J. Mehrara, Douglas S. Steinbrech, Jason A. Spector, Joshua A. Greenwald, Gyu S. Chin, Hikaru Ueno, George K. Gittes, and Michael T. Longaker

Mechanisms of Fibroblast Growth Factor-2 Modulation of Vascular Endothelial Growth Factor Expression by Osteoblastic Cells
Endocrinology 2000 141: 2075-2083, doi:10.1210/en.141.6.2075 [Abstract] [Full Text] [PDF]  

Samuel Varghese, Sheila Rydziel, and Ernesto Canalis

Basic Fibroblast Growth Factor Stimulates Collagenase-3 Promoter Activity in Osteoblasts through an Activator Protein-1-Binding Site
Endocrinology 2000 141: 2185-2191, doi:10.1210/en.141.6.2185 [Abstract] [Full Text] [PDF]  

Hideaki Miyake, Colleen Nelson, Paul S. Rennie, and Martin E. Gleave

Overexpression of Insulin-Like Growth Factor Binding Protein-5 Helps Accelerate Progression to Androgen-Independence in the Human Prostate LNCaP Tumor Model through Activation of Phosphatidylinositol 3'-Kinase Pathway
Endocrinology 2000 141: 2257-2265, doi:10.1210/en.141.6.2257 [Abstract] [Full Text] [PDF]  

INSULIN-GLUCAGON-GI PEPTIDES-DIABETES MELLITUS:

Don McClain

Introduction to the Diabetes Focus Issue of Endocrinology
Endocrinology 2000 141: 1916, doi:10.1210/en.141.6.1916 [Full Text] [PDF]  

Dominic J. Withers and Morris White

Perspective: The Insulin Signaling System—A Common Link in the Pathogenesis of Type 2 Diabetes
Endocrinology 2000 141: 1917-1921, doi:10.1210/en.141.6.1917 [Full Text] [PDF]  

Luciano Rossetti

Perspective: Hexosamines and Nutrient Sensing
Endocrinology 2000 141: 1922-1925, doi:10.1210/en.141.6.1922 [Full Text] [PDF]  

Susan Bonner-Weir

Perspective: Postnatal Pancreatic ß Cell Growth
Endocrinology 2000 141: 1926-1929, doi:10.1210/en.141.6.1926 [Full Text] [PDF]  

Margarzata Szayna, Máire E. Doyle, Jennifer A. Betkey, Harold W. Holloway, Richard G. S. Spencer, Nigel H. Greig, and Josephine M. Egan

Exendin-4 Decelerates Food Intake, Weight Gain, and Fat Deposition in Zucker Rats
Endocrinology 2000 141: 1936-1941, doi:10.1210/en.141.6.1936 [Abstract] [Full Text] [PDF]  

Errol D. Crook, Gregory Crenshaw, Geddati Veerababu, and Lalit P. Singh

Overexpression of Glutamine:Fructose-6-Phosphate Amidotransferase in Rat-1 Fibroblasts Enhances Glucose-Mediated Glycogen Accumulation via Suppression of Glycogen Phosphorylase Activity
Endocrinology 2000 141: 1962-1970, doi:10.1210/en.141.6.1962 [Abstract] [Full Text] [PDF]  

Gordon C. Yaney, Helen M. Korchak, and Barbara E. Corkey

Long-Chain Acyl CoA Regulation of Protein Kinase C and Fatty Acid Potentiation of Glucose-Stimulated Insulin Secretion in Clonal ß-Cells
Endocrinology 2000 141: 1989-1998, doi:10.1210/en.141.6.1989 [Abstract] [Full Text] [PDF]  

Donald A. McClain, Thomas Alexander, Robert C. Cooksey, and Robert V. Considine

Hexosamines Stimulate Leptin Production in Transgenic Mice
Endocrinology 2000 141: 1999-2002, doi:10.1210/en.141.6.1999 [Abstract] [Full Text] [PDF]  

Johan Saldeen

Cytokines Induce Both Necrosis and Apoptosis via a Common Bcl-2-Inhibitable Pathway in Rat Insulin-Producing Cells
Endocrinology 2000 141: 2003-2010, doi:10.1210/en.141.6.2003 [Abstract] [Full Text] [PDF]  

INTRACELLULAR SIGNAL SYSTEMS:

Katsuya Egawa, Naoki Nakashima, Prem M. Sharma, Hiroshi Maegawa, Yoshio Nagai, Atsunori Kashiwagi, Ryuichi Kikkawa, and Jerrold M. Olefsky

Persistent Activation of Phosphatidylinositol 3-Kinase Causes Insulin Resistance Due to Accelerated Insulin-Induced Insulin Receptor Substrate-1 Degradation in 3T3-L1 Adipocytes
Endocrinology 2000 141: 1930-1935, doi:10.1210/en.141.6.1930 [Abstract] [Full Text] [PDF]  

Dominique Sawka-Verhelle, Sophie Tartare-Deckert, Jean-François Decaux, Jean Girard, and Emmanuel Van Obberghen

Stat 5B, Activated by Insulin in a Jak-Independent Fashion, Plays a Role in Glucokinase Gene Transcription
Endocrinology 2000 141: 1977-1988, doi:10.1210/en.141.6.1977 [Abstract] [Full Text] [PDF]  

Thomas Morrison, Leslie Waggoner, Laura Whitworth-Langley, and Bradley J. Stith

Nongenomic Action of Progesterone: Activation of XenopusOocyte Phospholipase C through a Plasma Membrane-Associated Tyrosine Kinase
Endocrinology 2000 141: 2145-2152, doi:10.1210/en.141.6.2145 [Abstract] [Full Text] [PDF]  

Kuntala Shome, Mark A. Rizzo, Chandrasekaran Vasudevan, Bradley Andresen, and Guillermo Romero

The Activation of Phospholipase D by Endothelin-1, Angiotensin II, and Platelet-Derived Growth Factor in Vascular Smooth Muscle A10 Cells Is Mediated by Small G Proteins of the ADP-Ribosylation Factor Family
Endocrinology 2000 141: 2200-2208, doi:10.1210/en.141.6.2200 [Abstract] [Full Text] [PDF]  

C. Aguirre, F. C. L. Jayes, and J. D. Veldhuis

Luteinizing Hormone (LH) Drives Diverse Intracellular Calcium Second Messenger Signals in Isolated Porcine Ovarian Thecal Cells: Preferential Recruitment of Intracellular Ca²⁺ Oscillatory Cells by Higher Concentrations of LH
Endocrinology 2000 141: 2220-2228, doi:10.1210/en.141.6.2220 [Abstract] [Full Text] [PDF]  

NEUROENDOCRINOLOGY:

Lucía Núñez, Carlos Villalobos, F. R. Boockfor, and L. Stephen Frawley

The Relationship between Pulsatile Secretion and Calcium Dynamics in Single, Living Gonadotropin-Releasing Hormone Neurons
Endocrinology 2000 141: 2012-2017, doi:10.1210/en.141.6.2012 [Abstract] [Full Text] [PDF]  

Roberto Maggi, Federica Pimpinelli, Laura Molteni, Mario Milani, Luciano Martini, and Flavio Piva

Immortalized Luteinizing Hormone-Releasing Hormone Neurons Show a Different Migratory Activity in Vitro
Endocrinology 2000 141: 2105-2112, doi:10.1210/en.141.6.2105 [Abstract] [Full Text] [PDF]  

O. C. Meijer, P. J. Steenbergen, and E. R. de Kloet

Differential Expression and Regional Distribution of Steroid Receptor Coactivators SRC-1 and SRC-2 in Brain and Pituitary
Endocrinology 2000 141: 2192-2199, doi:10.1210/en.141.6.2192 [Abstract] [Full Text] [PDF]  

A. D. Taylor, J. G. Philip, C. D. John, P. O. Cover, J. F. Morris, R. J. Flower, and J. C. Buckingham

Annexin 1 (Lipocortin 1) Mediates the Glucocorticoid Inhibition of Cyclic Adenosine 3',5'-Monophosphate-Stimulated Prolactin Secretion
Endocrinology 2000 141: 2209-2219, doi:10.1210/en.141.6.2209 [Abstract] [Full Text] [PDF]  

PTH-CALCITONIN-VITAMIN D-BONE:

Yoshiyuki Sakai and Marie B. Demay

Evaluation of Keratinocyte Proliferation and Differentiation in Vitamin D Receptor Knockout Mice
Endocrinology 2000 141: 2043-2049, doi:10.1210/en.141.6.2043 [Abstract] [Full Text] [PDF]  

Xiaodong Li, Yosuke Okada, Carol C. Pilbeam, Joseph A. Lorenzo, Christopher R. J. Kennedy, Richard M. Breyer, and Lawrence G. Raisz

Knockout of the Murine Prostaglandin EP₂ Receptor Impairs Osteoclastogenesis in Vitro
Endocrinology 2000 141: 2054-2061, doi:10.1210/en.141.6.2054 [Abstract] [Full Text] [PDF]  

Andrew Grey, Yan Chen, Indu Paliwal, Kristen Carlberg, and Karl Insogna

Evidence for a Functional Association between Phosphatidylinositol 3-Kinase and c-src in the Spreading Response of Osteoclasts to Colony-Stimulating Factor-1
Endocrinology 2000 141: 2129-2138, doi:10.1210/en.141.6.2129 [Abstract] [Full Text] [PDF]  

Ningxia Zhao and Harriet S. Tenenhouse

Npt2 Gene Disruption Confers Resistance to the Inhibitory Action of Parathyroid Hormone on Renal Sodium-Phosphate Cotransport
Endocrinology 2000 141: 2159-2165, doi:10.1210/en.141.6.2159 [Abstract] [Full Text] [PDF]  

Gaby Palmer, Jerôme Guicheux, Jean-Philippe Bonjour, and Joseph Caverzasio

Transforming Growth Factor-ß Stimulates Inorganic Phosphate Transport and Expression of the Type III Phosphate Transporter Glvr-1 in Chondrogenic ATDC5 Cells
Endocrinology 2000 141: 2236-2243, doi:10.1210/en.141.6.2236 [Abstract] [Full Text] [PDF]  

RECEPTORS:

Stanley M. Hileman, Jens Tornøe, Jeffrey S. Flier, and Christian Bjørbæk

Transcellular Transport of Leptin by the Short Leptin Receptor Isoform ObRa in Madin-Darby Canine Kidney Cells
Endocrinology 2000 141: 1955-1961, doi:10.1210/en.141.6.1955 [Abstract] [Full Text] [PDF]  

Derek A. Schreihofer, Mark H. Stoler, and Margaret A. Shupnik

Differential Expression and Regulation of Estrogen Receptors (ERs) in Rat Pituitary and Cell Lines: Estrogen Decreases ER Protein and Estrogen Responsiveness
Endocrinology 2000 141: 2174-2184, doi:10.1210/en.141.6.2174 [Abstract] [Full Text] [PDF]  

Luisa Salvatori, Linda Ravenna, Maria Pia Felli, Maria Rosaria Cardillo, Matteo Antonio Russo, Luigi Frati, Alberto Gulino, and Elisa Petrangeli

Identification of an Estrogen-Mediated Deoxyribonucleic Acid-Binding Independent Transactivation Pathway on the Epidermal Growth Factor Receptor Gene Promoter
Endocrinology 2000 141: 2266-2274, doi:10.1210/en.141.6.2266 [Abstract] [Full Text] [PDF]  

Momoyo Kuno-Murata, Noriyuki Koibuchi, Harumi Fukuda, Mitsunobu Murata, and William W. Chin

Augmentation of Thyroid Hormone Receptor-Mediated Transcription by Ca²⁺/Calmodulin-Dependent Protein Kinase Type IV
Endocrinology 2000 141: 2275-2278, doi:10.1210/en.141.6.2275 [Abstract] [Full Text] [PDF]  

REPRODUCTION-DEVELOPMENT:

Priya S. Duggal, Kylie H. Van der Hoek, Clyde R. Milner, Natalie K. Ryan, David T. Armstrong, Denis A. Magoffin, and Robert J. Norman

The in Vivo and in Vitro Effects of Exogenous Leptin on Ovulation in the Rat
Endocrinology 2000 141: 1971-1976, doi:10.1210/en.141.6.1971 [Abstract] [Full Text] [PDF]  

Takashi Yazawa, Takashi Yamamoto, and Shin-Ichi Abé

Prolactin Induces Apoptosis in the Penultimate Spermatogonial Stage of the Testes in Japanese Red-Bellied Newt (Cynops pyrrhogaster)
Endocrinology 2000 141: 2027-2032, doi:10.1210/en.141.6.2027 [Abstract] [Full Text] [PDF]  

Margaret M. Hinshelwood, Margaret E. Smith, Barbara A. Murry, and Carole R. Mendelson

A 278 bp Region Just Upstream of the Human CYP19 (Aromatase) Gene Mediates Ovary-Specific Expression in Transgenic Mice
Endocrinology 2000 141: 2050-2053, doi:10.1210/en.141.6.2050 [Abstract] [Full Text] [PDF]  

Isabelle Goddard, Mourad Bouras, Michele Keramidas, Jean Claude Hendrick, Jean Jacques Feige, and Mohamed Benahmed

Transforming Growth Factor-ß Receptor Types I and II in Cultured Porcine Leydig Cells: Expression and Hormonal Regulation
Endocrinology 2000 141: 2068-2074, doi:10.1210/en.141.6.2068 [Abstract] [Full Text] [PDF]  

TRH-TSH-THYROID:

Paul Hobby, Andrzej Gardas, Roman Radomski, Alan M. McGregor, J. Paul Banga, and Brian J. Sutton

Identification of an Immunodominant Region Recognized by Human Autoantibodies in a Three-Dimensional Model of Thyroid Peroxidase
Endocrinology 2000 141: 2018-2026, doi:10.1210/en.141.6.2018 [Abstract] [Full Text] [PDF]  

Jongkyeong Chung, Eun Shin Park, Dohoon Kim, Jae Mi Suh, Hyo Kyun Chung, Jeonghoon Kim, Ho Kim, Soo Jung Park, O-Yu Kwon, Heung Kyu Ro, and Minho Shong

Thyrotropin Modulates Interferon--Mediated Intercellular Adhesion Molecule-1 Gene Expression by Inhibiting Janus Kinase-1 and Signal Transducer and Activator of Transcription-1 Activation in Thyroid Cells
Endocrinology 2000 141: 2090-2097, doi:10.1210/en.141.6.2090 [Abstract] [Full Text] [PDF]  

Kaie Ojamaa, Agnes Kenessey, and Irwin Klein

Thyroid Hormone Regulation of Phospholamban Phosphorylation in the Rat Heart
Endocrinology 2000 141: 2139-2144, doi:10.1210/en.141.6.2139 [Abstract] [Full Text] [PDF]  

MISCELLANEOUS:

Seymour Reichlin, GuanJie Chen, and Margery Nicolson

Blood to Brain Transfer of Leptin in Normal and Interleukin-1ß-Treated Male Rats
Endocrinology 2000 141: 1951-1954, doi:10.1210/en.141.6.1951 [Abstract] [Full Text] [PDF]  

Limin Liu and Jeffrey W. Smith

Identification of ADAM 31: A Protein Expressed in Leydig Cells and Specialized Epithelia
Endocrinology 2000 141: 2033-2042, doi:10.1210/en.141.6.2033 [Abstract] [Full Text] [PDF]  

Alejandro Losada, Juan A. Tovar, Hui M. Xia, Juan A. Diez-Pardo, and Pilar Santisteban

Down-Regulation of Thyroid Transcription Factor-1 Gene Expression in Fetal Lung Hypoplasia Is Restored by Glucocorticoids
Endocrinology 2000 141: 2166-2173, doi:10.1210/en.141.6.2166 [Abstract] [Full Text] [PDF]  

Gary R. Grotendorst, Lester F. Lau, and Bernard Perbal

CCN Proteins Are Distinct from and Should Not Be Considered Members of the Insulin-Like Growth Factor-Binding Protein Superfamily
Endocrinology 2000 141: 2254-2256, doi:10.1210/en.141.6.2254 [Full Text] [PDF]  

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