CANCER:

Lorella Bonaccorsi, Vinicio Carloni, Monica Muratori, Adriana Salvadori, Augusto Giannini, Marco Carini, Mario Serio, Gianni Forti, and Elisabetta Baldi

Androgen Receptor Expression in Prostate Carcinoma Cells Suppresses 6ß4 Integrin-Mediated Invasive Phenotype
Endocrinology 2000 141: 3172-3182, doi:10.1210/en.141.9.3172 [Abstract] [Full Text] [PDF]  

Sylvie Froidevaux, Axel Heppeler, Alex N. Eberle, Anne-Marie Meier, Marianne Häusler, Christoph Beglinger, Martin Béhé, Pia Powell, and Helmut R. Mäcke

Preclinical Comparison in AR4–2J Tumor-Bearing Mice of Four Radiolabeled 1,4,7,10-Tetraazacyclododecane-1,4,7,10-Tetraacetic Acid-Somatostatin Analogs for Tumor Diagnosis and Internal Radiotherapy
Endocrinology 2000 141: 3304-3312, doi:10.1210/en.141.9.3304 [Abstract] [Full Text] [PDF]  

T. D. Southgate, S. Windeatt, J. Smith-Arica, C. A. Gerdes, M. J. Perone, I. Morris, J. R. E. Davis, D. Klatzmann, P. R. Löwenstein, and M. G. Castro

Transcriptional Targeting to Anterior Pituitary Lactotrophic Cells Using Recombinant Adenovirus Vectors in Vitro and in Vivo in Normal and Estrogen/Sulpiride-Induced Hyperplasic Anterior Pituitaries
Endocrinology 2000 141: 3493-3505, doi:10.1210/en.141.9.3493 [Abstract] [Full Text] [PDF]  

CRH-ACTH-POMC-ADRENAL:

Armelle Logié, Philippe Boudou, Liliane Boccon-Gibod, Eric Baudin, Gilles Vassal, Martin Schlumberger, Yves Le Bouc, and Christine Gicquel

Establishment and Characterization of a Human Adrenocortical Carcinoma Xenograft Model
Endocrinology 2000 141: 3165-3171, doi:10.1210/en.141.9.3165 [Abstract] [Full Text] [PDF]  

Minako Morishita, Yasumasa Iwasaki, Etsuko Yamamori, Atsushi Nomura, Noriko Mutsuga, Masanori Yoshida, Masato Asai, Yutaka Oiso, and Hidehiko Saito

Antidiabetic Sulfonylurea Enhances Secretagogue-Induced Adrenocorticotropin Secretion and Proopiomelanocortin Gene Expression in Vitro
Endocrinology 2000 141: 3313-3318, doi:10.1210/en.141.9.3313 [Abstract] [Full Text] [PDF]  

GRH-SOMATOSTATIN-GH:

Hee K. Choi and David J. Waxman

Plasma Growth Hormone Pulse Activation of Hepatic JAK-STAT5 Signaling: Developmental Regulation and Role in Male-Specific Liver Gene Expression
Endocrinology 2000 141: 3245-3255, doi:10.1210/en.141.9.3245 [Abstract] [Full Text] [PDF]  

Liang Liang, Jing Jiang, and Stuart J. Frank

Insulin Receptor Substrate-1-Mediated Enhancement of Growth Hormone-Induced Mitogen-Activated Protein Kinase Activation
Endocrinology 2000 141: 3328-3336, doi:10.1210/en.141.9.3328 [Abstract] [Full Text] [PDF]  

K. Teoman Uysal, Ludger Scheja, Sarah M. Wiesbrock, Susan Bonner-Weir, and Gökhan S. Hotamisligil

Improved Glucose and Lipid Metabolism in Genetically Obese Mice Lacking aP2
Endocrinology 2000 141: 3388-3396, doi:10.1210/en.141.9.3388 [Abstract] [Full Text] [PDF]  

Douglas C. Harnish, Marshall S. Scicchitano, Steven J. Adelman, C. Richard Lyttle, and Sotirios K. Karathanasis

The Role of CBP in Estrogen Receptor Cross-Talk with Nuclear Factor-B in HepG2 Cells
Endocrinology 2000 141: 3403-3411, doi:10.1210/en.141.9.3403 [Abstract] [Full Text] [PDF]  

GROWTH FACTORS-CYTOKINES-ONCOGENES:

C. A. Conover, L. K. Bale, S. K. Durham, and D. R. Powell

Insulin-Like Growth Factor (IGF) Binding Protein-3 Potentiation of IGF Action Is Mediated through the Phosphatidylinositol-3-Kinase Pathway and Is Associated with Alteration in Protein Kinase B/AKT Sensitivity
Endocrinology 2000 141: 3098-3103, doi:10.1210/en.141.9.3098 [Abstract] [Full Text] [PDF]  

Houta Salahifar, Robert C. Baxter, and Janet L. Martin

Differential Regulation of Insulin-Like Growth Factor-Binding Protein-3 Protease Activity in MCF-7 Breast Cancer Cells by Estrogen and Transforming Growth Factor-ß1
Endocrinology 2000 141: 3104-3110, doi:10.1210/en.141.9.3104 [Abstract] [Full Text] [PDF]  

Nathalie Boulle, Christine Gicquel, Armelle Logié, Rémi Christol, Jean-Jacques Feige, and Yves Le Bouc

Fibroblast Growth Factor-2 Inhibits the Maturation of Pro-Insulin-Like Growth Factor-II (Pro-IGF-II) and the Expression of Insulin-Like Growth Factor Binding Protein-2 (IGFBP-2) in the Human Adrenocortical Tumor Cell Line NCI-H295R
Endocrinology 2000 141: 3127-3136, doi:10.1210/en.141.9.3127 [Abstract] [Full Text] [PDF]  

Robert A. Frost, Gerald J. Nystrom, and Charles H. Lang

Stimulation of Insulin-Like Growth Factor Binding Protein-1 Synthesis by Interleukin-1ß: Requirement of the Mitogen-Activated Protein Kinase Pathway
Endocrinology 2000 141: 3156-3164, doi:10.1210/en.141.9.3156 [Abstract] [Full Text] [PDF]  

Lee-Chuan C. Yeh and John C. Lee

Identification of an Osteogenic Protein-1 (Bone Morphogenetic Protein-7)-Responsive Element in the Promoter of the Rat Insulin-Like Growth Factor-Binding Protein-5 Gene
Endocrinology 2000 141: 3278-3286, doi:10.1210/en.141.9.3278 [Abstract] [Full Text] [PDF]  

Pascale H. Lane

5-Thio-D-Glucose Elevates Renal Transforming Growth Factor ß-1 at a Dose that Does Not Prevent Streptozocin Diabetes in Rats
Endocrinology 2000 141: 3337-3342, doi:10.1210/en.141.9.3337 [Abstract] [Full Text] [PDF]  

Diane M. Klotz, Sylvia Curtis Hewitt, Kenneth S. Korach, and Richard P. Diaugustine

Activation of a Uterine Insulin-Like Growth Factor I Signaling Pathway by Clinical and Environmental Estrogens: Requirement of Estrogen Receptor-
Endocrinology 2000 141: 3430-3439, doi:10.1210/en.141.9.3430 [Abstract] [Full Text] [PDF]  

INSULIN-GLUCAGON-GI PEPTIDES-DIABETES MELLITUS:

Wei Fan, Daniela M. Dinulescu, Andrew A. Butler, Jeanie Zhou, Daniel L. Marks, and Roger D. Cone

The Central Melanocortin System Can Directly Regulate Serum Insulin Levels
Endocrinology 2000 141: 3072-3079, doi:10.1210/en.141.9.3072 [Abstract] [Full Text] [PDF]  

Xun Qian, Subhash Prabhakar, Animesh Nandi, Sandhya S. Visweswariah, and Michael F. Goy

Expression of GC-C, a Receptor-Guanylate Cyclase, and Its Endogenous Ligands Uroguanylin and Guanylin along the Rostrocaudal Axis of the Intestine
Endocrinology 2000 141: 3210-3224, doi:10.1210/en.141.9.3210 [Abstract] [Full Text] [PDF]  

Walter S. Zawalich and Kathleen C. Zawalich

A Link between Insulin Resistance and Hyperinsulinemia: Inhibitors of Phosphatidylinositol 3-Kinase Augment Glucose-Induced Insulin Secretion from Islets of Lean, But Not Obese, Rats
Endocrinology 2000 141: 3287-3295, doi:10.1210/en.141.9.3287 [Abstract] [Full Text] [PDF]  

Octavio P. Luzardo, Rubén P. Machín, Bonifacio N. Díaz-Chico, and Leandro Fernández

Photoaffinity Labeling Identification of a Specific Binding Protein for the Anabolic Steroids Stanozolol and Danazol: An Oligomeric Protein Regulated by Age, Pituitary Hormones, and Ethinyl Estradiol
Endocrinology 2000 141: 3377-3387, doi:10.1210/en.141.9.3377 [Abstract] [Full Text] [PDF]  

INTRACELLULAR SIGNAL SYSTEMS:

Melanie S. Johnson, Eve M. Lutz, Christopher J. MacKenzie, W. Bart Wolbers, Derek N. Robertson, Pamela J. Holland, and Rory Mitchell

Gonadotropin-Releasing Hormone Receptor Activation of Extracellular Signal-Regulated Kinase and Tyrosine Kinases in Transfected GH3 Cells and in T3–1 Cells
Endocrinology 2000 141: 3087-3097, doi:10.1210/en.141.9.3087 [Abstract] [Full Text] [PDF]  

Gerald D. Frank, Satoru Eguchi, Tadashi Yamakawa, Shun-ichi Tanaka, Tadashi Inagami, and Evangeline D. Motley

Involvement of Reactive Oxygen Species in the Activation of Tyrosine Kinase and Extracellular Signal-Regulated Kinase by Angiotensin II
Endocrinology 2000 141: 3120-3126, doi:10.1210/en.141.9.3120 [Abstract] [Full Text] [PDF]  

NEUROENDOCRINOLOGY:

Marie J. Gibson, Latanya Ingraham, and Areta Dobrjansky

Soluble Factors Guide Gonadotropin-Releasing Hormone Axonal Targeting to the Median Eminence
Endocrinology 2000 141: 3065-3071, doi:10.1210/en.141.9.3065 [Abstract] [Full Text] [PDF]  

Ming Xu, Janice H. Urban, Jennifer W. Hill, and Jon E. Levine

Regulation of Hypothalamic Neuropeptide Y Y1 Receptor Gene Expression during the Estrous Cycle: Role of Progesterone Receptors
Endocrinology 2000 141: 3319-3327, doi:10.1210/en.141.9.3319 [Abstract] [Full Text] [PDF]  

Hélène Castel, Sylvie Jégou, Marie-Christine Tonon, and Hubert Vaudry

Regulation of the GABA_A Receptor by Nitric Oxide in Frog Pituitary Melanotrophs
Endocrinology 2000 141: 3451-3460, doi:10.1210/en.141.9.3451 [Abstract] [Full Text] [PDF]  

Min S. Lee, Yong Lian Zhu, Zhenyu Sun, Harrison Rhee, Andreas Jeromin, John Roder, and Priscilla S. Dannies

Accumulation of Synaptosomal-Associated Protein of 25 kDa (SNAP-25) and Other Proteins Associated with the Secretory Pathway in GH₄C₁ Cells Upon Treatment with Estradiol, Insulin, and Epidermal Growth Factor
Endocrinology 2000 141: 3485-3492, doi:10.1210/en.141.9.3485 [Abstract] [Full Text] [PDF]  

Erik Hrabovszky, Paul J. Shughrue, István Merchenthaler, Tibor Hajszán, Clifford D. Carpenter, Zsolt Liposits, and Sandra L. Petersen

Detection of Estrogen Receptor-ß Messenger Ribonucleic Acid and ¹²⁵I-Estrogen Binding Sites in Luteinizing Hormone-Releasing Hormone Neurons of the Rat Brain
Endocrinology 2000 141: 3506-3509, doi:10.1210/en.141.9.3506 [Abstract] [Full Text] [PDF]  

Andrew A. Butler, Robert A. Kesteson, Kathy Khong, Mary Jane Cullen, Mary Ann Pelleymounter, Jenefer Dekoning, Manfred Baetscher, and Roger D. Cone

A Unique Metalolic Sysdrone Causes Obesity in the Melanocortin-3 Receptor-Deficient Mouse
Endocrinology 2000 141: 3518-3521, doi:10.1210/en.141.9.3518 [Abstract] [Full Text] [PDF]  

PTH-CALCITONIN-VITAMIN D-BONE:

Sam R. J. Hoare, David A. Rubin, Harald Jüppner, and Ted B. Usdin

Evaluating the Ligand Specificity of Zebrafish Parathyroid Hormone (PTH) Receptors: Comparison of PTH, PTH-Related Protein, and Tuberoinfundibular Peptide of 39 Residues
Endocrinology 2000 141: 3080-3086, doi:10.1210/en.141.9.3080 [Abstract] [Full Text] [PDF]  

S. Bourrin, P. Ammann, J. P. Bonjour, and R. Rizzoli

Dietary Protein Restriction Lowers Plasma Insulin-Like Growth Factor I (IGF-I), Impairs Cortical Bone Formation, and Induces Osteoblastic Resistance to IGF-I in Adult Female Rats
Endocrinology 2000 141: 3149-3155, doi:10.1210/en.141.9.3149 [Abstract] [Full Text] [PDF]  

John W. Morgan, Nicola Kouttab, Dwayne Ford, and Abby L. Maizel

Vitamin D-Mediated Gene Regulation in Phenotypically Defined Human B Cell Subpopulations
Endocrinology 2000 141: 3225-3234, doi:10.1210/en.141.9.3225 [Abstract] [Full Text] [PDF]  

Nobuyuki Udagawa, Naoyuki Takahashi, Hisataka Yasuda, Atsuko Mizuno, Kanami Itoh, Yutaka Ueno, Toshimasa Shinki, Matthew T. Gillespie, T. John Martin, Kanji Higashio, and Tatsuo Suda

Osteoprotegerin Produced by Osteoblasts Is an Important Regulator in Osteoclast Development and Function
Endocrinology 2000 141: 3478-3484, doi:10.1210/en.141.9.3478 [Abstract] [Full Text] [PDF]  

RECEPTORS:

Hassan M. A. M. Qazzaz, M. Adnan El-Masri, and Roland Valdes, Jr.

Secretion of a Lactone-Hydrogenated Ouabain-Like Effector of Sodium, Potassium-Adenosine Triphosphatase Activity by Adrenal Cells
Endocrinology 2000 141: 3200-3209, doi:10.1210/en.141.9.3200 [Abstract] [Full Text] [PDF]  

Zhongting Hu, Vincent Lelievre, Jimmy Tam, Jennifer W. Cheng, Gabriel Fuenzalida, Xinrong Zhou, and James A. Waschek

Molecular Cloning of Growth Hormone-Releasing Hormone/Pituitary Adenylyl Cyclase-Activating Polypeptide in the Frog Xenopus laevis: Brain Distribution and Regulation after Castration
Endocrinology 2000 141: 3366-3376, doi:10.1210/en.141.9.3366 [Abstract] [Full Text] [PDF]  

Søren Tullin, Birgit Sehested Hansen, Michael Ankersen, Jette Møller, Karen Arevad von Cappelen, and Lars Thim

Adenosine Is an Agonist of the Growth Hormone Secretagogue Receptor
Endocrinology 2000 141: 3397-3402, doi:10.1210/en.141.9.3397 [Abstract] [Full Text] [PDF]  

Judith L. Turgeon and Dennis W. Waring

Progesterone Regulation of the Progesterone Receptor in Rat Gonadotropes
Endocrinology 2000 141: 3422-3429, doi:10.1210/en.141.9.3422 [Abstract] [Full Text] [PDF]  

Jiann-an Tan, Susan H. Hall, Peter Petrusz, and Frank S. French

Thyroid Receptor Activator Molecule, TRAM-1, Is an Androgen Receptor Coactivator
Endocrinology 2000 141: 3440-3450, doi:10.1210/en.141.9.3440 [Abstract] [Full Text] [PDF]  

REPRODUCTION-DEVELOPMENT:

Michael H. Melner and Kenneth S. Korach

Editorial: A New Database for Tissue-Specific Gene Expression and Function in the Ovary
Endocrinology 2000 141: 3051, doi:10.1210/en.141.9.3051 [Full Text] [PDF]  

Chandra P. Leo, Ursula A. Vitt, and Aaron J. W. Hsueh

The Ovarian Kaleidoscope Database: An Online Resource for the Ovarian Research Community
Endocrinology 2000 141: 3052-3054, doi:10.1210/en.141.9.3052 [Abstract] [Full Text] [PDF]  

Noureddine Boujrad, Branislav Vidic, Maria Gazouli, Martine Culty, and Vassilios Papadopoulos

The Peroxisome Proliferator Perfluorodecanoic Acid Inhibits the Peripheral-Type Benzodiazepine Receptor (PBR) Expression and Hormone-Stimulated Mitochondrial Cholesterol Transport and Steroid Formation in Leydig Cells
Endocrinology 2000 141: 3137-3148, doi:10.1210/en.141.9.3137 [Abstract] [Full Text] [PDF]  

Qifa Wang, Henry T. Keutmann, Alan L. Schneyer, and Patrick M. Sluss

Analysis of Human Follistatin Structure: Identification of Two Discontinuous N-Terminal Sequences Coding for Activin A Binding and Structural Consequences of Activin Binding to Native Proteins
Endocrinology 2000 141: 3183-3193, doi:10.1210/en.141.9.3183 [Abstract] [Full Text] [PDF]  

Tonia Doerksen, Guylaine Benoit, and Jacquetta M. Trasler

Deoxyribonucleic Acid Hypomethylation of Male Germ Cells by Mitotic and Meiotic Exposure to 5-Azacytidine Is Associated with Altered Testicular Histology
Endocrinology 2000 141: 3235-3244, doi:10.1210/en.141.9.3235 [Abstract] [Full Text] [PDF]  

Mohammed El Majdoubi, Abhiram Sahu, and Tony M. Plant

Changes in Hypothalamic Gene Expression Associated with the Arrest of Pulsatile Gonadotropin-Releasing Hormone Release during Infancy in the Agonadal Male Rhesus Monkey (Macaca mulatta)
Endocrinology 2000 141: 3273-3277, doi:10.1210/en.141.9.3273 [Abstract] [Full Text] [PDF]  

Dino A. Giussani, Susan L. Jenkins, James A. Winter, Jennifer D. Tame, and Peter W. Nathanielsz

Androstenedione Treatment of Pregnant Baboons at 0.7–0.8 of Gestation Promotes a Premature Forward Shift in the Nocturnal Maternal Plasma Estradiol Surge Relative to Progesterone and Increases Myometrial Contraction Activity
Endocrinology 2000 141: 3296-3303, doi:10.1210/en.141.9.3296 [Abstract] [Full Text] [PDF]  

In-Taek Hwang, Yong-Hun Lee, Boung-Cheon Moon, Kyu-Youn Ahn, See-Woo Lee, and Jong-Yoon Chun

Identification and Characterization of a New Member of the Placental Prolactin-Like Protein-C (PLP-C) Subfamily, PLP-Cß
Endocrinology 2000 141: 3343-3352, doi:10.1210/en.141.9.3343 [Abstract] [Full Text] [PDF]  

Nao Hattori, Hiroshi Fujiwara, Michiyuki Maeda, Shingo Fujii, and Masamichi Ueda

Epoxide Hydrolase Affects Estrogen Production in the Human Ovary
Endocrinology 2000 141: 3353-3365, doi:10.1210/en.141.9.3353 [Abstract] [Full Text] [PDF]  

Harminder K. Deol, Robin Varghese, Graham F. Wagner, and Gabriel E. DiMattia

Dynamic Regulation of Mouse Ovarian Stanniocalcin Expression during Gestation and Lactation
Endocrinology 2000 141: 3412-3421, doi:10.1210/en.141.9.3412 [Abstract] [Full Text] [PDF]  

Nicole A. Grieshaber, Scott Boitano, InHae Ji, Jennie P. Mather, and Tae H. Ji

Differentiation of Granulosa Cell Line: Follicle-Stimulating Hormone Induces Formation of Lamellipodia and Filopodia via the Adenylyl Cyclase/Cyclic Adenosine Monophosphate Signal
Endocrinology 2000 141: 3461-3470, doi:10.1210/en.141.9.3461 [Abstract] [Full Text] [PDF]  

Renea A. Jarred, Belinda Cancilla, Gail S. Prins, Kristina A. Thayer, Gerald R. Cunha, and Gail P. Risbridger

Evidence That Estrogens Directly Alter Androgen-Regulated Prostate Development
Endocrinology 2000 141: 3471-3477, doi:10.1210/en.141.9.3471 [Abstract] [Full Text] [PDF]  

Rozana M. Popovici, Lee-Chuan Kao, and Linda C. Giudice

Discovery of New Inducible Genes in in vitroDecidualized Human Endometrial Stromal Cells Using Microarray Technology
Endocrinology 2000 141: 3510-3515, doi:10.1210/en.141.9.3510 [Abstract] [Full Text] [PDF]  

TRH-TSH-THYROID:

Mitchell A. Lazar

Editorial: A Sweetheart Deal for Thyroid Hormone
Endocrinology 2000 141: 3055-3056, doi:10.1210/en.141.9.3055 [Full Text] [PDF]  

Susanne U. Trost, Eric Swanson, Bernd Gloss, David B. Wang-Iverson, Hongjiang Zhang, Tanya Volodarsky, Gary J. Grover, John D. Baxter, Grazia Chiellini, Thomas S. Scanlan, and Wolfgang H. Dillmann

The Thyroid Hormone Receptor-ß-Selective Agonist GC-1 Differentially Affects Plasma Lipids and Cardiac Activity
Endocrinology 2000 141: 3057-3064, doi:10.1210/en.141.9.3057 [Abstract] [Full Text] [PDF]  

Qiao-Ling Li, Erik Jansen, Gregory A. Brent, Syed Naqvi, John F. Wilber, and Theodore C. Friedman

Interactions between the Prohormone Convertase 2 Promoter and the Thyroid Hormone Receptor
Endocrinology 2000 141: 3256-3266, doi:10.1210/en.141.9.3256 [Abstract] [Full Text] [PDF]  

Joana Almeida Palha, Rui Fernandes, Gabriella Morreale de Escobar, Vasso Episkopou, Max Gottesman, and Maria João Saraiva

Transthyretin Regulates Thyroid Hormone Levels in the Choroid Plexus, But Not in the Brain Parenchyma: Study in a Transthyretin-Null Mouse Model
Endocrinology 2000 141: 3267-3272, doi:10.1210/en.141.9.3267 [Abstract] [Full Text] [PDF]  

Meng Zhang, Kim Phuong T. Tong, Valerie Fremont, Judy Chen, Perma Narayan, David Puett, Bruce D. Weintraub, and Mariusz W. Szkudlinski

The Extracellular Domain Suppresses Constitutive Activity of the Transmembrane Domain of the Human TSH Receptor: Implications for Hormone-Receptor Interaction and Antagonist Design
Endocrinology 2000 141: 3514-3517, doi:10.1210/en.141.9.3514 [Abstract] [Full Text] [PDF]  

MISCELLANEOUS:

H. C. Christian, N. J. Rolls, and J. F. Morris

Nongenomic Actions of Testosterone on a Subset of Lactotrophs in the Male Rat Pituitary
Endocrinology 2000 141: 3111-3119, doi:10.1210/en.141.9.3111 [Abstract] [Full Text] [PDF]  

Nozomu Nishi, Hiroki Shoji, Hiroshi Miyanaka, and Takanori Nakamura

Androgen-Regulated Expression of a Novel Member of the Aldo-Keto Reductase Superfamily in Regrowing Rat Prostate
Endocrinology 2000 141: 3194-3199, doi:10.1210/en.141.9.3194 [Abstract] [Full Text] [PDF]  

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