CANCER:

Wei Yue, Ji-Ping Wang, Mark Conaway, Shigeru Masamura, Yuebai Li, and Richard J. Santen

Activation of the MAPK Pathway Enhances Sensitivity of MCF-7 Breast Cancer Cells to the Mitogenic Effect of Estradiol
Endocrinology 2002 143: 3221-3229, doi:10.1210/en.2002-220186 [Abstract] [Full Text] [PDF]  

Kimberly R. Kalli, Oluwole I. Falowo, Laurie K. Bale, Michael A. Zschunke, Patrick C. Roche, and Cheryl A. Conover

Functional Insulin Receptors on Human Epithelial Ovarian Carcinoma Cells: Implications for IGF-II Mitogenic Signaling
Endocrinology 2002 143: 3259-3267, doi:10.1210/en.2001-211408 [Abstract] [Full Text] [PDF]  

Caisheng Ye, Chong Feng, Shenming Wang, Xiaoning Liu, Yongjie Lin, and Mengfeng Li

Antiangiogenic and Antitumor Effects of Endostatin on Follicular Thyroid Carcinoma
Endocrinology 2002 143: 3522-3528, doi:10.1210/en.2002-220439 [Abstract] [Full Text] [PDF]  

Natalia Danilovich, Indrojit Roy, and M. Ram Sairam

Emergence of Uterine Pathology during Accelerated Biological Aging in FSH Receptor-Haploinsufficient Mice
Endocrinology 2002 143: 3618-3627, doi:10.1210/en.2001-211402 [Abstract] [Full Text] [PDF]  

Erin L. Milliken, Rebecca K. Ameduri, Melissa D. Landis, Alireza Behrooz, Fadi W. Abdul-Karim, and Ruth A. Keri

Ovarian Hyperstimulation by LH Leads to Mammary Gland Hyperplasia and Cancer Predisposition in Transgenic Mice
Endocrinology 2002 143: 3671-3680, doi:10.1210/en.2002-220228 [Abstract] [Full Text] [PDF]  

CRH-ACTH-POMC-ADRENAL:

Hong Li, Michèle Brochu, Shu Pei Wang, Leila Rochdi, Mylène Côté, Grant Mitchell, and Nicole Gallo-Payet

Hormone-Sensitive Lipase Deficiency in Mice Causes Lipid Storage in the Adrenal Cortex and Impaired Corticosterone Response to Corticotropin Stimulation
Endocrinology 2002 143: 3333-3340, doi:10.1210/en.2002-220341 [Abstract] [Full Text] [PDF]  

GRH-SOMATOSTATIN-GH:

Hideki Tamura, Jun Kamegai, Takako Shimizu, Shinya Ishii, Hitoshi Sugihara, and Shinichi Oikawa

Ghrelin Stimulates GH But Not Food Intake in Arcuate Nucleus Ablated Rats
Endocrinology 2002 143: 3268-3275, doi:10.1210/en.2002-220268 [Abstract] [Full Text] [PDF]  

Yoav E. Timsit and David S. Riddick

Stimulation of Hepatic Signal Transducer and Activator of Transcription 5b by GH Is Not Altered by 3-Methylcholanthrene
Endocrinology 2002 143: 3284-3294, doi:10.1210/en.2002-220212 [Abstract] [Full Text] [PDF]  

Hiroyuki Ariyasu, Kazuhiko Takaya, Hiroshi Hosoda, Hiroshi Iwakura, Ken Ebihara, Kiyoshi Mori, Yoshihiro Ogawa, Kiminori Hosoda, Takashi Akamizu, Masayasu Kojima, Kenji Kangawa, and Kazuwa Nakao

Delayed Short-Term Secretory Regulation of Ghrelin in Obese Animals: Evidenced by a Specific RIA for the Active Form of Ghrelin
Endocrinology 2002 143: 3341-3350, doi:10.1210/en.2002-220225 [Abstract] [Full Text] [PDF]  

Hiroyuki Kaiya, Serge van der Geyten, Masayasu Kojima, Hiroshi Hosoda, Yasuo Kitajima, Masaru Matsumoto, Sofie Geelissen, Veerle M. Darras, and Kenji Kangawa

Chicken Ghrelin: Purification, cDNA Cloning, and Biological Activity
Endocrinology 2002 143: 3454-3463, doi:10.1210/en.2002-220255 [Abstract] [Full Text] [PDF]  

Herve Tostivint, Didier Vieau, Nicolas Chartrel, Isabelle Boutelet, Ludovic Galas, Alain Fournier, Isabelle Lihrmann, and Hubert Vaudry

Expression and Processing of the [Pro²,Met¹³]Somatostatin-14 Precursor in the Intermediate Lobe of the Frog Pituitary
Endocrinology 2002 143: 3472-3481, doi:10.1210/en.2002-220406 [Abstract] [Full Text] [PDF]  

Amir S. Khan, Marta L. Fiorotto, Leigh-Anne Hill, P. Brandon Malone, Kathleen K. Cummings, Deena Parghi, Robert J. Schwartz, Roy G. Smith, and Ruxandra Draghia-Akli

Nonhereditary Enhancement of Progeny Growth
Endocrinology 2002 143: 3561-3567, doi:10.1210/en.2002-220282 [Abstract] [Full Text] [PDF]  

Eyleen L. K. Goh, Tao Zhu, Wan-Ying Leong, and Peter E. Lobie

c-Cbl Is a Negative Regulator of GH-Stimulated STAT5-Mediated Transcription
Endocrinology 2002 143: 3590-3603, doi:10.1210/en.2002-220374 [Abstract] [Full Text] [PDF]  

GROWTH FACTORS-CYTOKINES-ONCOGENES:

Tytti M. Ahola, Tommi Manninen, Niina Alkio, and Timo Ylikomi

G Protein-Coupled Receptor 30 Is Critical for a Progestin-Induced Growth Inhibition in MCF-7 Breast Cancer Cells
Endocrinology 2002 143: 3376-3384, doi:10.1210/en.2001-211445 [Abstract] [Full Text] [PDF]  

INSULIN-GLUCAGON-GI PEPTIDES-DIABETES MELLITUS:

Gil Leibowitz, Gökhan Üçkaya, Andrei I. Oprescu, Erol Cerasi, David J. Gross, and Nurit Kaiser

Glucose-Regulated Proinsulin Gene Expression Is Required for Adequate Insulin Production during Chronic Glucose Exposure
Endocrinology 2002 143: 3214-3220, doi:10.1210/en.2002-220174 [Abstract] [Full Text] [PDF]  

Cynthia L. Kelpe, Lisa M. Johnson, and Vincent Poitout

Increasing Triglyceride Synthesis Inhibits Glucose-Induced Insulin Secretion in Isolated Rat Islets of Langerhans: A Study Using Adenoviral Expression of Diacylglycerol Acyltransferase
Endocrinology 2002 143: 3326-3332, doi:10.1210/en.2002-220402 [Abstract] [Full Text] [PDF]  

Miriam Cnop, Jean Claude Hannaert, Annick Y. Grupping, and Daniel G. Pipeleers

Low Density Lipoprotein Can Cause Death of Islet ß-Cells by Its Cellular Uptake and Oxidative Modification
Endocrinology 2002 143: 3449-3453, doi:10.1210/en.2002-220273 [Abstract] [Full Text] [PDF]  

F. A. Adatia, L. L. Baggio, Q. Xiao, D. J. Drucker, and P. L. Brubaker

Cellular Specificity of Proexendin-4 Processing in Mammalian Cells in Vitro and in Vivo
Endocrinology 2002 143: 3464-3471, doi:10.1210/en.2002-220251 [Abstract] [Full Text] [PDF]  

Jin-Lin Wang, Xueming Qian, Narumol Chinookoswong, John Lu, Gwyneth Chow, Lars E. Theill, and Zhi-Qing Shi

Polyethylene Glycolated Recombinant TNF Receptor I Improves Insulitis and Reduces Incidence of Spontaneous and Cyclophosphamide-Accelerated Diabetes in Nonobese Diabetic Mice
Endocrinology 2002 143: 3490-3497, doi:10.1210/en.2002-220412 [Abstract] [Full Text] [PDF]  

Anandwardhan A. Hardikar, Xiao Yang Wang, Lindy J. Williams, Juliana Kwok, Rose Wong, Mu Yao, and Bernard E. Tuch

Functional Maturation of Fetal Porcine ß-Cells by Glucagon-Like Peptide 1 and Cholecystokinin
Endocrinology 2002 143: 3505-3514, doi:10.1210/en.2001-211344 [Abstract] [Full Text] [PDF]  

Hongxiang Hui, Run Yu, Corinne Bousquet, and Riccardo Perfetti

Transfection of Pancreatic-Derived ß-Cells with a Minigene Encoding for Human Glucagon-Like Peptide-1 Regulates Glucose-Dependent Insulin Synthesis and Secretion
Endocrinology 2002 143: 3529-3539, doi:10.1210/en.2001-210979 [Abstract] [Full Text] [PDF]  

You-Qing Zhang, Hui Zhang, Akito Maeshima, Hideyuki Kurihara, Jun-ichiro Miyagawa, Toshiyuki Takeuchi, and Itaru Kojima

Up-Regulation of the Expression of Activins in the Pancreatic Duct by Reduction of the ß-Cell Mass
Endocrinology 2002 143: 3540-3547, doi:10.1210/en.2002-220089 [Abstract] [Full Text] [PDF]  

Anath Shalev, Cynthia A. Pise-Masison, Michael Radonovich, Steven C. Hoffmann, Boaz Hirshberg, John N. Brady, and David M. Harlan

Oligonucleotide Microarray Analysis of Intact Human Pancreatic Islets: Identification of Glucose-Responsive Genes and a Highly Regulated TGFß Signaling Pathway
Endocrinology 2002 143: 3695, doi:10.1210/en.2002-220564 [Abstract] [PDF]  

INTRACELLULAR SIGNAL SYSTEMS:

Hyunjung Lim and Sudhansu K. Dey

Minireview: A Novel Pathway of Prostacyclin Signaling—Hanging Out with Nuclear Receptors
Endocrinology 2002 143: 3207-3210, doi:10.1210/en.2002-220159 [Abstract] [Full Text] [PDF]  

Manuela Aragno, Raffaella Mastrocola, Enrico Brignardello, Maria Catalano, Gaia Robino, Roberta Manti, Maurizio Parola, Oliviero Danni, and Giuseppe Boccuzzi

Dehydroepiandrosterone Modulates Nuclear Factor-B Activation in Hippocampus of Diabetic Rats
Endocrinology 2002 143: 3250-3258, doi:10.1210/en.2002-220182 [Abstract] [Full Text] [PDF]  

Laurence Walch and Patricia L. Morris

Cyclooxygenase 2 Pathway Mediates IL-1ß Regulation of IL-1, -1ß, and IL-6 mRNA Levels in Leydig Cell Progenitors
Endocrinology 2002 143: 3276-3283, doi:10.1210/en.2002-220410 [Abstract] [Full Text] [PDF]  

Vyacheslav V. Vasilyev, Mark A. Lawson, Donna Dipaolo, Nicholas J. G. Webster, and Pamela L. Mellon

Different Signaling Pathways Control Acute Induction versus Long-Term Repression of LHß Transcription by GnRH
Endocrinology 2002 143: 3414-3426, doi:10.1210/en.2001-211215 [Abstract] [Full Text] [PDF]  

Carlos Villalobos, Lucía Núñez, William J. Faught, David C. Leaumont, Fredric R. Boockfor, and L. Stephen Frawley

Calcium Dynamics and Resting Transcriptional Activity Regulates Prolactin Gene Expression
Endocrinology 2002 143: 3548-3554, doi:10.1210/en.2002-220266 [Abstract] [Full Text] [PDF]  

Robin C. Humphreys, Brian Bierie, Ling Zhao, Regina Raz, David Levy, and Lothar Hennighausen

Deletion of Stat3 Blocks Mammary Gland Involution and Extends Functional Competence of the Secretory Epithelium in the Absence of Lactogenic Stimuli
Endocrinology 2002 143: 3641-3650, doi:10.1210/en.2002-220224 [Abstract] [Full Text] [PDF]  

NEUROENDOCRINOLOGY:

Serge Rivest

Editorial: Does Circulating Leptin Have the Ability to Cross the Blood-Brain Barrier and Target Neurons Directly?
Endocrinology 2002 143: 3211-3213, doi:10.1210/en.2002-220655 [Full Text] [PDF]  

Laura L. Burger, Alan C. Dalkin, Kevin W. Aylor, Daniel J. Haisenleder, and John C. Marshall

GnRH Pulse Frequency Modulation of Gonadotropin Subunit Gene Transcription in Normal Gonadotropes—Assessment by Primary Transcript Assay Provides Evidence for Roles of GnRH and Follistatin
Endocrinology 2002 143: 3243-3249, doi:10.1210/en.2002-220216 [Abstract] [Full Text] [PDF]  

P. Giacobini, C. Giampietro, M. Fioretto, R. Maggi, A. Cariboni, I. Perroteau, and A. Fasolo

Hepatocyte Growth Factor/Scatter Factor Facilitates Migration of GN-11 Immortalized LHRH Neurons
Endocrinology 2002 143: 3306-3315, doi:10.1210/en.2002-220146 [Abstract] [Full Text] [PDF]  

Toru Hosoi, Toru Kawagishi, Yasunobu Okuma, Jun Tanaka, and Yasuyuki Nomura

Brain Stem Is a Direct Target for Leptin’s Action in the Central Nervous System
Endocrinology 2002 143: 3498-3504, doi:10.1210/en.2002-220077 [Abstract] [Full Text] [PDF]  

Brooke H. Miller and Andrea C. Gore

N-Methyl-D-Aspartate Receptor Subunit Expression in GnRH Neurons Changes during Reproductive Senescence in the Female Rat
Endocrinology 2002 143: 3568-3574, doi:10.1210/en.2002-220346 [Abstract] [Full Text] [PDF]  

M. Candolfi, V. Zaldivar, A. De Laurentiis, G. Jaita, D. Pisera, and A. Seilicovich

TNF- Induces Apoptosis of Lactotropes from Female Rats
Endocrinology 2002 143: 3611-3617, doi:10.1210/en.2002-220377 [Abstract] [Full Text] [PDF]  

PTH-CALCITONIN-VITAMIN D-BONE:

M. Sato, J. Vahle, A. Schmidt, M. Westmore, S. Smith, E. Rowley, and L. Y. Ma

Abnormal Bone Architecture and Biomechanical Properties with Near-Lifetime Treatment of Rats with PTH
Endocrinology 2002 143: 3230-3242, doi:10.1210/en.2002-220149 [Abstract] [Full Text] [PDF]  

Karen Sooy and Marie B. Demay

Transcriptional Repression of the Rat Osteocalcin Gene by EF1
Endocrinology 2002 143: 3370-3375, doi:10.1210/en.2001-211441 [Abstract] [Full Text] [PDF]  

Masae Naruse, Yoko Ishihara, Sachiko Miyagawa-Tomita, Atsushi Koyama, and Hiromi Hagiwara

3-Methylcholanthrene, Which Binds to the Arylhydrocarbon Receptor, Inhibits Proliferation and Differentiation of Osteoblasts in Vitro and Ossification in Vivo
Endocrinology 2002 143: 3575-3581, doi:10.1210/en.2002-220003 [Abstract] [Full Text] [PDF]  

Edith Bonnelye, Vanessa Kung, Catherine Laplace, Deborah L. Galson, and Jane E. Aubin

Estrogen Receptor-Related Receptor Impinges on the Estrogen Axis in Bone: Potential Function in Osteoporosis
Endocrinology 2002 143: 3658-3670, doi:10.1210/en.2002-220095 [Abstract] [Full Text] [PDF]  

Ellen H. Filvaroff, Susan Guillet, Constance Zlot, Min Bao, Gladys Ingle, Hope Steinmetz, John Hoeffel, Stuart Bunting, Jed Ross, Richard A. D. Carano, Lyn Powell-Braxton, Graham F. Wagner, Renee Eckert, Mary E. Gerritsen, and Dorothy M. French

Stanniocalcin 1 Alters Muscle and Bone Structure and Function in Transgenic Mice
Endocrinology 2002 143: 3681-3690, doi:10.1210/en.2001-211424 [Abstract] [Full Text] [PDF]  

Megan M. Donohue and Marie B. Demay

Rickets in VDR Null Mice Is Secondary to Decreased Apoptosis of Hypertrophic Chondrocytes
Endocrinology 2002 143: 3691, doi:10.1210/en.2002-220454 [Abstract] [PDF]  

RECEPTORS:

Heike Brand, Martin Kos, Stefanie Denger, Gilles Flouriot, Jörg Gromoll, Frank Gannon, and George Reid

A Novel Promoter Is Involved in the Expression of Estrogen Receptor in Human Testis and Epididymis
Endocrinology 2002 143: 3397-3404, doi:10.1210/en.2001-210832 [Abstract] [Full Text] [PDF]  

Yves Le Drean, Nathalie Mincheneau, Pascale Le Goff, and Denis Michel

Potentiation of Glucocorticoid Receptor Transcriptional Activity by Sumoylation
Endocrinology 2002 143: 3482-3489, doi:10.1210/en.2002-220135 [Abstract] [Full Text] [PDF]  

Gail S. Prins, William Y. Chang, Yan Wang, and Richard B. van Breemen

Retinoic Acid Receptors and Retinoids Are Up-Regulated in the Developing and Adult Rat Prostate by Neonatal Estrogen Exposure
Endocrinology 2002 143: 3628-3640, doi:10.1210/en.2002-220184 [Abstract] [Full Text] [PDF]  

RENIN-MINERALOCORTICOIDS-ANF-ADH:

Ana Fortuño, Amaia Rodríguez, Javier Gómez-Ambrosi, Paula Muñiz, Javier Salvador, Javier Díez, and Gema Frühbeck

Leptin Inhibits Angiotensin II-Induced Intracellular Calcium Increase and Vasoconstriction in the Rat Aorta
Endocrinology 2002 143: 3555-3560, doi:10.1210/en.2002-220075 [Abstract] [Full Text] [PDF]  

Takashi Miyazawa, Yoshihiro Ogawa, Hideki Chusho, Akihiro Yasoda, Naohisa Tamura, Yasato Komatsu, Alexander Pfeifer, Franz Hofmann, and Kazuwa Nakao

Cyclic GMP-Dependent Protein Kinase II Plays a Critical Role in C-Type Natriuretic Peptide-Mediated Endochondral Ossification
Endocrinology 2002 143: 3604-3610, doi:10.1210/en.2002-220307 [Abstract] [Full Text] [PDF]  

Jennifer C. Condon, Vincenzo Pezzi, Brad M. Drummond, Su Yin, and William E. Rainey

Calmodulin-Dependent Kinase I Regulates Adrenal Cell Expression of Aldosterone Synthase
Endocrinology 2002 143: 3651-3657, doi:10.1210/en.2001-211359 [Abstract] [Full Text] [PDF]  

REPRODUCTION-DEVELOPMENT:

Christopher R. Harlow, Lindsay Davidson, Kathleen H. Burns, Changning Yan, Martin M. Matzuk, and Stephen G. Hillier

FSH and TGF-ß Superfamily Members Regulate Granulosa Cell Connective Tissue Growth Factor Gene Expression in Vitro and in Vivo
Endocrinology 2002 143: 3316-3325, doi:10.1210/en.2001-211389 [Abstract] [Full Text] [PDF]  

V. Matt Laurich, Alexander M. Trbovich, Francis H. O’Neill, Christopher P. Houk, Patrick M. Sluss, Anita H. Payne, Patricia K. Donahoe, and Jose Teixeira

Müllerian Inhibiting Substance Blocks the Protein Kinase A-Induced Expression of Cytochrome P450 17-Hydroxylase/C_17–20 Lyase mRNA in a Mouse Leydig Cell Line Independent of cAMP Responsive Element Binding Protein Phosphorylation
Endocrinology 2002 143: 3351-3360, doi:10.1210/en.2001-211352 [Abstract] [Full Text] [PDF]  

F. M. Moran, J. J. Ford, C. J. Corbin, S. M. Mapes, V. C. Njar, A. M. Brodie, and A. J. Conley

Regulation of Microsomal P450, Redox Partner Proteins, and Steroidogenesis in the Developing Testes of the Neonatal Pig
Endocrinology 2002 143: 3361-3369, doi:10.1210/en.2002-220329 [Abstract] [Full Text] [PDF]  

Gunapala Shetty, Gene Wilson, Matthew P. Hardy, Enmei Niu, Ilpo Huhtaniemi, and Marvin L. Meistrich

Inhibition of Recovery of Spermatogenesis in Irradiated Rats by Different Androgens
Endocrinology 2002 143: 3385-3396, doi:10.1210/en.2002-220206 [Abstract] [Full Text] [PDF]  

A. L. Johnson, J. S. Langer, and J. T. Bridgham

Survivin as a Cell Cycle-Related and Antiapoptotic Protein in Granulosa Cells
Endocrinology 2002 143: 3405-3413, doi:10.1210/en.2002-220107 [Abstract] [Full Text] [PDF]  

Hong-Zheng Zhang, Jessica M. Bennett, Kyle T. Smith, Nityanand Sunil, and Sandra Z. Haslam

Estrogen Mediates Mammary Epithelial Cell Proliferation in Serum-Free Culture Indirectly via Mammary Stroma-Derived Hepatocyte Growth Factor
Endocrinology 2002 143: 3427-3434, doi:10.1210/en.2002-220007 [Abstract] [Full Text] [PDF]  

Pierre Val, Antoine Martinez, Isabelle Sahut-Barnola, Claude Jean, Georges Veyssière, and Anne-Marie Lefrançois-Martinez

A 77-Base Pair LINE-Like Sequence Elicits Androgen-Dependent mvdp/akr1-b7 Expression in Mouse Vas Deferens, But Is Dispensable for Adrenal Expression in Rats
Endocrinology 2002 143: 3435-3448, doi:10.1210/en.2002-220293 [Abstract] [Full Text] [PDF]  

Victoria A. Cavicchio, James K. Pru, Benjamin S. Davis, John S. Davis, Bo R. Rueda, and David H. Townson

Secretion of Monocyte Chemoattractant Protein-1 by Endothelial Cells of the Bovine Corpus Luteum: Regulation by Cytokines But Not Prostaglandin F2
Endocrinology 2002 143: 3582-3589, doi:10.1210/en.2002-220388 [Abstract] [Full Text] [PDF]  

Lisa Edwards, Teija Peura, Katrina Hartwich, Skye Rudiger, I. Caroline McMillen, and Simon Walker

Postnatal Growth and Circulating ACTH and Cortisol Concentratoins during the First Month of Life in Cloned Lambs
Endocrinology 2002 143: 3699, doi:10.1210/en.2002-220500 [Abstract] [PDF]  

TRH-TSH-THYROID:

J. David Furlow and Akira Kanamori

The Transcription Factor Basic Transcription Element-Binding Protein 1 Is a Direct Thyroid Hormone Response Gene in the Frog Xenopus laevis
Endocrinology 2002 143: 3295-3305, doi:10.1210/en.2002-220126 [Abstract] [Full Text] [PDF]  

MISCELLANEOUS:

Takeshi Tokudome, Takeshi Horio, Fumiki Yoshihara, Shin-ichi Suga, Yuhei Kawano, Masakazu Kohno, and Kenji Kangawa

Adrenomedullin Inhibits Doxorubicin-Induced Cultured Rat Cardiac Myocyte Apoptosis via a cAMP-Dependent Mechanism
Endocrinology 2002 143: 3515-3521, doi:10.1210/en.2002-220233 [Abstract] [Full Text] [PDF]  

ANNOUNCEMENTS:

THIRD INTERNATIONAL SYMPOSIUM ON VERTEBRATE SEX DETERMINATION
Endocrinology 2002 143: 3229 [Abstract] [Full Text] [PDF]  

STADY III—International Symposium on Signal Transduction in Health and Disease
Endocrinology 2002 143: 3481 [Abstract] [Full Text] [PDF]  

RESEARCH RESOURCES:

Endocrine-Related Resources from the National Institutes of Health
Endocrinology 2002 143: 3703-3705 [Full Text] [PDF]  

National Hormone & Peptide Program - NIDDK: Peptides Hormones, Subunits, Antisera & Other Reagents Available
Endocrinology 2002 143: 3706-3708 [Abstract] [Full Text] [PDF]  

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