NEWS & VIEWS:

Ali S. Calikoglu

Adrenocorticotropic Hormone, a New Player in the Control of Testicular Steroidogenesis
Endocrinology 2003 144: 3277-3278, doi:10.1210/en.2003-0618 [Full Text] [PDF]  

Ernestina Schipani

Otoconin-22 and Calcitonin: A Novel Modality of Regulating Calcium Storages in Lower Vertebrates?
Endocrinology 2003 144: 3285-3286, doi:10.1210/en.2003-0473 [Full Text] [PDF]  

BRIEF COMMUNICATIONS:

Ishwar S. Parhar, Satoshi Ogawa, Tomohiro Hamada, and Yasuo Sakuma

Single-Cell Real-Time Quantitative Polymerase Chain Reaction of Immunofluorescently Identified Neurons of Gonadotropin-Releasing Hormone Subtypes in Cichlid Fish
Endocrinology 2003 144: 3297-3300, doi:10.1210/en.2003-0386 [Abstract] [Full Text] [PDF]  

Carlos Stocco, Jean Djiane, and Geula Gibori

Prostaglandin F₂ (PGF₂) and Prolactin Signaling: PGF₂-Mediated Inhibition of Prolactin Receptor Expression in the Corpus Luteum
Endocrinology 2003 144: 3301-3305, doi:10.1210/en.2003-0420 [Abstract] [Full Text] [PDF]  

CANCER:

Trevor G. Shepherd and Mark W. Nachtigal

Identification of a Putative Autocrine Bone Morphogenetic Protein-Signaling Pathway in Human Ovarian Surface Epithelium and Ovarian Cancer Cells
Endocrinology 2003 144: 3306-3314, doi:10.1210/en.2003-0185 [Abstract] [Full Text] [PDF]  

C. Spitzweg, I. V. Scholz, E. R. Bergert, D. J. Tindall, C. Y. F. Young, B. Göke, and J. C. Morris

Retinoic Acid-Induced Stimulation of Sodium Iodide Symporter Expression and Cytotoxicity of Radioiodine in Prostate Cancer Cells
Endocrinology 2003 144: 3423-3432, doi:10.1210/en.2002-0206 [Abstract] [Full Text] [PDF]  

Wing-Shing Cheng, Valeria Giandomenico, Ira Pastan, and Magnus Essand

Characterization of the Androgen-Regulated Prostate-Specific T Cell Receptor -Chain Alternate Reading Frame Protein (TARP) Promoter
Endocrinology 2003 144: 3433-3440, doi:10.1210/en.2003-0121 [Abstract] [Full Text] [PDF]  

Josh D. Silvertown, Brad J. Geddes, and Alastair J. S. Summerlee

Adenovirus-Mediated Expression of Human Prorelaxin Promotes the Invasive Potential of Canine Mammary Cancer Cells
Endocrinology 2003 144: 3683-3691, doi:10.1210/en.2003-0248 [Abstract] [Full Text] [PDF]  

CRH-ACTH-POMC-ADRENAL:

Tomoko Chiyo, Takeshi Yamazaki, Kenji Aoshika, Shiro Kominami, and Yoshihiro Ohta

Corticosterone Enhances Adrenocorticotropin-Induced Calcium Signals in Bovine Adrenocortical Cells
Endocrinology 2003 144: 3376-3381, doi:10.1210/en.2002-221126 [Abstract] [Full Text] [PDF]  

ENERGY BALANCE/OBESITY:

Afia Naaz, Srikanth Yellayi, Melissa A. Zakroczymski, David Bunick, Daniel R. Doerge, Dennis B. Lubahn, William G. Helferich, and Paul S. Cooke

The Soy Isoflavone Genistein Decreases Adipose Deposition in Mice
Endocrinology 2003 144: 3315-3320, doi:10.1210/en.2003-0076 [Abstract] [Full Text] [PDF]  

GENERAL ENDOCRINOLOGY:

Anthony J. Lee, May Xiaoxin Cai, Paul E. Thomas, Allan H. Conney, and Bao Ting Zhu

Characterization of the Oxidative Metabolites of 17ß-Estradiol and Estrone Formed by 15 Selectively Expressed Human Cytochrome P450 Isoforms
Endocrinology 2003 144: 3382-3398, doi:10.1210/en.2003-0192 [Abstract] [Full Text] [PDF]  

Yulin Li, Kaori Iida, Jeff O’Neil, Peichuan Zhang, Sheng’ai Li, Ami Frank, Aryn Gabai, Frank Zambito, Shun-Hsin Liang, Clifford J. Rosen, and Douglas R. Cavener

PERK eIF2 Kinase Regulates Neonatal Growth by Controlling the Expression of Circulating Insulin-Like Growth Factor-I Derived from the Liver
Endocrinology 2003 144: 3505-3513, doi:10.1210/en.2003-0236 [Abstract] [Full Text] [PDF]  

S. J. Yarram, M. J. Perry, T. J. Christopher, K. Westby, N. L. Brown, T. Lamminen, S. B. Rulli, F.-P. Zhang, I. Huhtaniemi, J. R. Sandy, and J. P. Mansell

Luteinizing Hormone Receptor Knockout (LuRKO) Mice and Transgenic Human Chorionic Gonadotropin (hCG)-Overexpressing Mice (hCG ß+) Have Bone Phenotypes
Endocrinology 2003 144: 3555-3564, doi:10.1210/en.2003-0036 [Abstract] [Full Text] [PDF]  

GENETICS/GENOMICS:

Tommaso Simoncini, Paolo Mannella, Letizia Fornari, Gaetano Varone, Antonella Caruso, and Andrea R. Genazzani

Dehydroepiandrosterone Modulates Endothelial Nitric Oxide Synthesis Via Direct Genomic and Nongenomic Mechanisms
Endocrinology 2003 144: 3449-3455, doi:10.1210/en.2003-0044 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

GRH-SOMATOSTATIN-GH:

Al Hassan Casse, Dominique Desplanches, Marie Hélène Mayet-Sornay, Mireille Raccurt, Sylvie Jegou, and Gérard Morel

Growth Hormone Receptor Expression in Atrophying Muscle Fibers of Rats
Endocrinology 2003 144: 3692-3697, doi:10.1210/en.2003--0311 [Abstract] [Full Text] [PDF]  

GROWTH FACTORS-CYTOKINES-ONCOGENES:

Nicholas Underhill-Day, Lisa A. McGovern, Natalia Karpovich, Helen J. Mardon, Victoria A. Barton, and John K. Heath

Functional Characterization of W147A: A High-Affinity Interleukin-11 Antagonist
Endocrinology 2003 144: 3406-3414, doi:10.1210/en.2002-0144 [Abstract] [Full Text] [PDF]  

Subburaman Mohan, Godfred Masinde, Xinmin Li, and David J. Baylink

Mapping Quantitative Trait Loci That Influence Serum Insulin-Like Growth Factor Binding Protein-5 Levels in F2 Mice (MRL/MpJ X SJL/J)
Endocrinology 2003 144: 3491-3496, doi:10.1210/en.2003-0042 [Abstract] [Full Text] [PDF]  

Monika Chabicovsky, Kurt Herkner, and Walter Rossmanith

Overexpression of Activin ß_C or Activin ß_E in the Mouse Liver Inhibits Regenerative Deoxyribonucleic Acid Synthesis of Hepatic Cells
Endocrinology 2003 144: 3497-3504, doi:10.1210/en.2003-0388 [Abstract] [Full Text] [PDF]  

INSULIN-GLUCAGON-GI PEPTIDES-DIABETES MELLITUS:

Soon H. Song, Christopher J. Rhodes, Johannes D. Veldhuis, and Peter C. Butler

Diazoxide Attenuates Glucose-Induced Defects in First-Phase Insulin Release and Pulsatile Insulin Secretion in Human Islets
Endocrinology 2003 144: 3399-3405, doi:10.1210/en.2003-0056 [Abstract] [Full Text] [PDF]  

Anna L. Scarim, Sheri Y. Nishimoto, Sarah M. Weber, and John A. Corbett

Role for c-Jun N-Terminal Kinase in ß-Cell Recovery from Nitric Oxide-Mediated Damage
Endocrinology 2003 144: 3415-3422, doi:10.1210/en.2002-0112 [Abstract] [Full Text] [PDF]  

Elke Clynen, Jurgen Huybrechts, Geert Baggerman, Jan Van Doorn, Dick Van der Horst, Arnold De Loof, and Liliane Schoofs

Identification of a Glycogenolysis-Inhibiting Peptide from the Corpora Cardiaca of Locusts
Endocrinology 2003 144: 3441-3448, doi:10.1210/en.2002-0107 [Abstract] [Full Text] [PDF]  

Peter J. Voshol, Guenter Haemmerle, D. Margriet Ouwens, Robert Zimmermann, Rudolf Zechner, Bas Teusink, J. Antonie Maassen, Louis M. Havekes, and Johannes A. Romijn

Increased Hepatic Insulin Sensitivity Together with Decreased Hepatic Triglyceride Stores in Hormone-Sensitive Lipase-Deficient Mice
Endocrinology 2003 144: 3456-3462, doi:10.1210/en.2002-0036 [Abstract] [Full Text] [PDF]  

Christina Christoffersen, Entela Bollano, Marie L. S. Lindegaard, Emil D. Bartels, Jens P. Goetze, Claus B. Andersen, and Lars B. Nielsen

Cardiac Lipid Accumulation Associated with Diastolic Dysfunction in Obese Mice
Endocrinology 2003 144: 3483-3490, doi:10.1210/en.2003-0242 [Abstract] [Full Text] [PDF]  

Thomas K. Graves and Patricia M. Hinkle

Ca²⁺-Induced Ca²⁺ Release in the Pancreatic ß-Cell: Direct Evidence of Endoplasmic Reticulum Ca²⁺ Release
Endocrinology 2003 144: 3565-3574, doi:10.1210/en.2002-0104 [Abstract] [Full Text] [PDF]  

INTRACELLULAR SIGNAL SYSTEMS:

XingJia Wang, Matthew T. Dyson, Youngah Jo, and Douglas M. Stocco

Inhibition of Cyclooxygenase-2 Activity Enhances Steroidogenesis and Steroidogenic Acute Regulatory Gene Expression in MA-10 Mouse Leydig Cells
Endocrinology 2003 144: 3368-3375, doi:10.1210/en.2002-0081 [Abstract] [Full Text] [PDF]  

Pavlos Pissios, Daniel J. Trombly, Iphigenia Tzameli, and Eleftheria Maratos-Flier

Melanin-Concentrating Hormone Receptor 1 Activates Extracellular Signal-Regulated Kinase and Synergizes with G_s-Coupled Pathways
Endocrinology 2003 144: 3514-3523, doi:10.1210/en.2002-0004 [Abstract] [Full Text] [PDF]  

Eva Biener, Cyril Martin, Nathalie Daniel, Stuart J. Frank, Victoria E. Centonze, Brian Herman, Jean Djiane, and Arieh Gertler

Ovine Placental Lactogen-Induced Heterodimerization of Ovine Growth Hormone and Prolactin Receptors in Living Cells Is Demonstrated by Fluorescence Resonance Energy Transfer Microscopy and Leads to Prolonged Phosphorylation of Signal Transducer and Activator of Transcription (STAT)1 and STAT3
Endocrinology 2003 144: 3532-3540, doi:10.1210/en.2003-0096 [Abstract] [Full Text] [PDF]  

Manuel Estrada, Alejandra Espinosa, Marioly Müller, and Enrique Jaimovich

Testosterone Stimulates Intracellular Calcium Release and Mitogen-Activated Protein Kinases Via a G Protein-Coupled Receptor in Skeletal Muscle Cells
Endocrinology 2003 144: 3586-3597, doi:10.1210/en.2002-0164 [Abstract] [Full Text] [PDF]  

NEUROENDOCRINOLOGY:

A. K. Ho, M. Mackova, C. Cho, and C. L. Chik

Regulation of 90-Kilodalton Ribosomal S6 Kinase Phosphorylation in the Rat Pineal Gland
Endocrinology 2003 144: 3344-3350, doi:10.1210/en.2003-0215 [Abstract] [Full Text] [PDF]  

Niren R. Thanky, Ruth Slater, and Allan E. Herbison

Sex Differences in Estrogen-Dependent Transcription of Gonadotropin-Releasing Hormone (GnRH) Gene Revealed in GnRH Transgenic Mice
Endocrinology 2003 144: 3351-3358, doi:10.1210/en.2001-211342 [Abstract] [Full Text] [PDF]  

Takashi Matsuwaki, Erina Watanabe, Masatoshi Suzuki, Keitaro Yamanouchi, and Masugi Nishihara

Glucocorticoid Maintains Pulsatile Secretion of Luteinizing Hormone under Infectious Stress Condition
Endocrinology 2003 144: 3477-3482, doi:10.1210/en.2002-221111 [Abstract] [Full Text] [PDF]  

Takayuki Masaki, Go Yoshimichi, Seiichi Chiba, Tohru Yasuda, Hitoshi Noguchi, Tetsuya Kakuma, Toshiie Sakata, and Hironobu Yoshimatsu

Corticotropin-Releasing Hormone-Mediated Pathway of Leptin to Regulate Feeding, Adiposity, and Uncoupling Protein Expression in Mice
Endocrinology 2003 144: 3547-3554, doi:10.1210/en.2003-0301 [Abstract] [Full Text] [PDF]  

Lydia L. DonCarlos, Daniel Garcia-Ovejero, Sara Sarkey, Luis Miguel Garcia-Segura, and Iñigo Azcoitia

Androgen Receptor Immunoreactivity in Forebrain Axons and Dendrites in the Rat
Endocrinology 2003 144: 3632-3638, doi:10.1210/en.2002-0105 [Abstract] [Full Text] [PDF]  

Heiko T. Jansen, Christopher Cutter, Steven Hardy, Michael N. Lehman, and Robert L. Goodman

Seasonal Plasticity within the Gonadotropin-Releasing Hormone (GnRH) System of the Ewe: Changes in Identified GnRH Inputs and Glial Association
Endocrinology 2003 144: 3663-3676, doi:10.1210/en.2002-0188 [Abstract] [Full Text] [PDF]  

PTH-CALCITONIN-VITAMIN D-BONE:

Yuichi Yaoi, Masakazu Suzuki, Hideaki Tomura, Yuichi Sasayama, Sakae Kikuyama, and Shigeyasu Tanaka

Molecular Cloning of Otoconin-22 Complementary Deoxyribonucleic Acid in the Bullfrog Endolymphatic Sac: Effect of Calcitonin on Otoconin-22 Messenger Ribonucleic Acid Levels
Endocrinology 2003 144: 3287-3296, doi:10.1210/en.2002-0181 [Abstract] [Full Text] [PDF]  

Nasreen Azam, Martin Y. H. Zhang, Xuemei Wang, Harriet S. Tenenhouse, and Anthony A. Portale

Disordered Regulation of Renal 25-Hydroxyvitamin D-1-Hydroxylase Gene Expression by Phosphorus in X-Linked Hypophosphatemic (Hyp) Mice
Endocrinology 2003 144: 3463-3468, doi:10.1210/en.2003-0255 [Abstract] [Full Text] [PDF]  

Sun-Kyeong Lee, Judith F. Kalinowski, Sandra L. Jastrzebski, Lynn Puddington, and Joseph A. Lorenzo

Interleukin-7 Is a Direct Inhibitor of in Vitro Osteoclastogenesis
Endocrinology 2003 144: 3524-3531, doi:10.1210/en.2002-221057 [Abstract] [Full Text] [PDF]  

Gang-Qing Yao, Jain-Jun Wu, Ben-Hua Sun, Nancy Troiano, Mary Ann Mitnick, and Karl Insogna

The Cell Surface Form of Colony-Stimulating Factor-1 Is Biologically Active in Bone in Vivo
Endocrinology 2003 144: 3677-3682, doi:10.1210/en.2002-221071 [Abstract] [Full Text] [PDF]  

RECEPTORS:

Elaine T. Alarid, Mara T. Preisler-Mashek, and Natalia M. Solodin

Thyroid Hormone Is an Inhibitor of Estrogen-Induced Degradation of Estrogen Receptor- Protein: Estrogen-Dependent Proteolysis Is Not Essential for Receptor Transactivation Function in the Pituitary
Endocrinology 2003 144: 3469-3476, doi:10.1210/en.2002-0092 [Abstract] [Full Text] [PDF]  

Li Xu, Qiang Pan-Hammarström, Asta Försti, Kari Hemminki, Lennart Hammarström, Damian Labuda, Jan-Åke Gustafsson, and Karin Dahlman-Wright

Human Estrogen Receptor ß 548 Is Not a Common Variant in Three Distinct Populations
Endocrinology 2003 144: 3541-3546, doi:10.1210/en.2002-0118 [Abstract] [Full Text] [PDF]  

RENIN-MINERALOCORTICOIDS-ANF-ADH:

Ping Ye, Christopher J. Kenyon, Scott M. MacKenzie, Jonathan R. Seckl, Robert Fraser, John M. C. Connell, and Eleanor Davies

Regulation of Aldosterone Synthase Gene Expression in the Rat Adrenal Gland and Central Nervous System by Sodium and Angiotensin II
Endocrinology 2003 144: 3321-3328, doi:10.1210/en.2003-0109 [Abstract] [Full Text] [PDF]  

Liomar A. A. Neves, Aleck F. Williams, David B. Averill, Carlos M. Ferrario, Michael P. Walkup, and K. Bridget Brosnihan

Pregnancy Enhances the Angiotensin (Ang)-(1–7) Vasodilator Response in Mesenteric Arteries and Increases the Renal Concentration and Urinary Excretion of Ang-(1–7)
Endocrinology 2003 144: 3338-3343, doi:10.1210/en.2003-0009 [Abstract] [Full Text] [PDF]  

REPRODUCTION-DEVELOPMENT:

P. J. O’Shaughnessy, L. M. Fleming, G. Jackson, U. Hochgeschwender, P. Reed, and P. J. Baker

Adrenocorticotropic Hormone Directly Stimulates Testosterone Production by the Fetal and Neonatal Mouse Testis
Endocrinology 2003 144: 3279-3284, doi:10.1210/en.2003-0277 [Abstract] [Full Text] [PDF]  

Phillip Kezele and Michael K. Skinner

Regulation of Ovarian Primordial Follicle Assembly and Development by Estrogen and Progesterone: Endocrine Model of Follicle Assembly
Endocrinology 2003 144: 3329-3337, doi:10.1210/en.2002-0131 [Abstract] [Full Text] [PDF]  

Sara Fiorini, Maria E. Ferretti, Carla Biondi, Barbara Pavan, Laura Lunghi, Guglielmo Paganetto, and Luigi Abelli

17ß-Estradiol Stimulates Arachidonate Release from Human Amnion-Like WISH Cells through a Rapid Mechanism Involving a Membrane Receptor
Endocrinology 2003 144: 3359-3367, doi:10.1210/en.2002-221106 [Abstract] [Full Text] [PDF]  

J. Bispham, G. S. Gopalakrishnan, J. Dandrea, V. Wilson, H. Budge, D. H. Keisler, F. Broughton Pipkin, T. Stephenson, and M. E. Symonds

Maternal Endocrine Adaptation throughout Pregnancy to Nutritional Manipulation: Consequences for Maternal Plasma Leptin and Cortisol and the Programming of Fetal Adipose Tissue Development
Endocrinology 2003 144: 3575-3585, doi:10.1210/en.2003-0320 [Abstract] [Full Text] [PDF]  

Allison E. Falender, Rainer Lanz, Daniel Malenfant, Luc Belanger, and JoAnne S. Richards

Differential Expression of Steroidogenic Factor-1 and FTF/LRH-1 in the Rodent Ovary
Endocrinology 2003 144: 3598-3610, doi:10.1210/en.2002-0137 [Abstract] [Full Text] [PDF]  

Kui Liu, Qiang Feng, Hong-Juan Gao, Zhao-Yuan Hu, Ru-Jin Zou, Yin-Chuan Li, and Yi-Xun Liu

Expression and Regulation of Plasminogen Activators, Plasminogen Activator Inhibitor Type-1, and Steroidogenic Acute Regulatory Protein in the Rhesus Monkey Corpus Luteum
Endocrinology 2003 144: 3611-3617, doi:10.1210/en.2003-0304 [Abstract] [Full Text] [PDF]  

Mitsumori Kawaminami, Yutaka Shibata, Akiko Yaji, Shiro Kurusu, and Inoru Hashimoto

Prolactin Inhibits Annexin 5 Expression and Apoptosis in the Corpus Luteum of Pseudopregnant Rats: Involvement of Local Gonadotropin-Releasing Hormone
Endocrinology 2003 144: 3625-3631, doi:10.1210/en.2003-0118 [Abstract] [Full Text] [PDF]  

Shannon M. Gifford, Jackie M. Cale, Stephen Tsoi, Ronald R. Magness, and Ian M. Bird

Pregnancy-Specific Changes in Uterine Artery Endothelial Cell Signaling in Vivo Are Both Programmed and Retained in Primary Culture
Endocrinology 2003 144: 3639-3650, doi:10.1210/en.2002-0006 [Abstract] [Full Text] [PDF] [Supplemental Table]  

Céline J. Guigon, Séverine Mazaud, Maguelone G. Forest, Sylvie Brailly-Tabard, Noëlline Coudouel, and Solange Magre

Unaltered Development of the Initial Follicular Waves and Normal Pubertal Onset in Female Rats after Neonatal Deletion of the Follicular Reserve
Endocrinology 2003 144: 3651-3662, doi:10.1210/en.2003-0072 [Abstract] [Full Text] [PDF]  

TRH-TSH-THYROID:

H. Fagman, M. Grände, J. Edsbagge, H. Semb, and M. Nilsson

Expression of Classical Cadherins in Thyroid Development: Maintenance of an Epithelial Phenotype throughout Organogenesis
Endocrinology 2003 144: 3618-3624, doi:10.1210/en.2003-0393 [Abstract] [Full Text] [PDF]  

RESEARCH RESOURCES:

Endocrine-Related Resources from the National Institutes of Health
Endocrinology 2003 144: 3712-3714 [Full Text] [PDF]  

National Hormone and Peptide Program (NHPP): New Recombinant Hormones, Hypothalamic Peptides, Natural Hormones, New Antisera, & Expanded Hormone Assay Services Available
Endocrinology 2003 144: 3715-3717 [Full Text] [PDF]  

THE ENDOCRINE SOCIETY:

The Endocrine Society Awards
Endocrinology 2003 144: 3698-3699 [Full Text] [PDF]  

THE ENDOCRINE SOCIETY 2003 ANNUAL AWARDS
Endocrinology 2003 144: 3700-3711 [Full Text] [PDF]  

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