MINIREVIEWS:

Jeffrey M. Zigman and Joel K. Elmquist

Minireview: From Anorexia to Obesity—The Yin and Yang of Body Weight Control
Endocrinology 2003 144: 3749-3756, doi:10.1210/en.2003-0241 [Abstract] [Full Text] [PDF]  

Stephen O’Rahilly, I. Sadaf Farooqi, Giles S. H. Yeo, and Benjamin G. Challis

Minireview: Human Obesity—Lessons from Monogenic Disorders
Endocrinology 2003 144: 3757-3764, doi:10.1210/en.2003-0373 [Abstract] [Full Text] [PDF]  

Michael W. Rajala and Philipp E. Scherer

Minireview: The Adipocyte—At the Crossroads of Energy Homeostasis, Inflammation, and Atherosclerosis
Endocrinology 2003 144: 3765-3773, doi:10.1210/en.2003-0580 [Abstract] [Full Text] [PDF]  

NEWS & VIEWS:

William H. Walker

Molecular Mechanisms Controlling Sertoli Cell Proliferation and Differentiation
Endocrinology 2003 144: 3719-3721, doi:10.1210/en.2003-0765 [Full Text] [PDF]  

Gregory F. Ball and Jacques Balthazart

Birds Return Every Spring Like Clockwork, but Where Is the Clock?
Endocrinology 2003 144: 3739-3741, doi:10.1210/en.2003-0781 [Full Text] [PDF]  

BRIEF COMMUNICATIONS:

Sabrina Diano, Balazs Horvath, Henryk F. Urbanski, Peter Sotonyi, and Tamas L. Horvath

Fasting Activates the Nonhuman Primate Hypocretin (Orexin) System and Its Postsynaptic Targets
Endocrinology 2003 144: 3774-3778, doi:10.1210/en.2003-0274 [Abstract] [Full Text] [PDF]  

Nadine Binart, Nathalie Melaine, Charles Pineau, Henri Kercret, Anne Marie Touzalin, Prune Imbert-Bolloré, Paul A. Kelly, and Bernard Jégou

Male Reproductive Function Is Not Affected in Prolactin Receptor-Deficient Mice
Endocrinology 2003 144: 3779-3782, doi:10.1210/en.2003-0409 [Abstract] [Full Text] [PDF]  

CANCER:

Wen-Bin Zhong, Chih-Yuan Wang, Tien-Chun Chang, and Wen-Sen Lee

Lovastatin Induces Apoptosis of Anaplastic Thyroid Cancer Cells via Inhibition of Protein Geranylgeranylation and de Novo Protein Synthesis
Endocrinology 2003 144: 3852-3859, doi:10.1210/en.2003-0098 [Abstract] [Full Text] [PDF]  

Malgorzata Bielinska, Helka Parviainen, Susan B. Porter-Tinge, Sanne Kiiveri, Elena Genova, Nafis Rahman, Ilpo T. Huhtaniemi, Louis J. Muglia, Markku Heikinheimo, and David B. Wilson

Mouse Strain Susceptibility to Gonadectomy-Induced Adrenocortical Tumor Formation Correlates with the Expression of GATA-4 and Luteinizing Hormone Receptor
Endocrinology 2003 144: 4123-4133, doi:10.1210/en.2003-0126 [Abstract] [Full Text] [PDF]  

Peter Kossmehl, Mehdi Shakibaei, Augusto Cogoli, Manfred Infanger, Francesco Curcio, Johann Schönberger, Christoph Eilles, Johann Bauer, Holger Pickenhahn, Gundula Schulze-Tanzil, Martin Paul, and Daniela Grimm

Weightlessness Induced Apoptosis in Normal Thyroid Cells and Papillary Thyroid Carcinoma Cells via Extrinsic and Intrinsic Pathways
Endocrinology 2003 144: 4172-4179, doi:10.1210/en.2002-0171 [Abstract] [Full Text] [PDF]  

ENERGY BALANCE/OBESITY:

Kylie N. Hewitt, Wah Chin Boon, Yoko Murata, Margaret E. E. Jones, and Evan R. Simpson

The Aromatase Knockout Mouse Presents with a Sexually Dimorphic Disruption to Cholesterol Homeostasis
Endocrinology 2003 144: 3895-3903, doi:10.1210/en.2003-0244 [Abstract] [Full Text] [PDF]  

Caroline R. Abbott, Adam R. Kennedy, Alison M. Wren, Michela Rossi, Kevin G. Murphy, Leighton J. Seal, Jeannie F. Todd, Mohammad A. Ghatei, Caroline J. Small, and Stephen R. Bloom

Identification of Hypothalamic Nuclei Involved in the Orexigenic Effect of Melanin-Concentrating Hormone
Endocrinology 2003 144: 3943-3949, doi:10.1210/en.2003-0149 [Abstract] [Full Text] [PDF]  

Catherine B. Lawrence, Torrie Williams, and Simon M. Luckman

Intracerebroventricular Galanin-Like Peptide Induces Different Brain Activation Compared with Galanin
Endocrinology 2003 144: 3977-3984, doi:10.1210/en.2003-0391 [Abstract] [Full Text] [PDF]  

GENERAL ENDOCRINOLOGY:

Xiao-Ming Gao, Alex Agrotis, Dominic J. Autelitano, Elodie Percy, Elizabeth A. Woodcock, Garry L. Jennings, Anthony M. Dart, and Xiao-Jun Du

Sex Hormones and Cardiomyopathic Phenotype Induced by Cardiac ß₂-Adrenergic Receptor Overexpression
Endocrinology 2003 144: 4097-4105, doi:10.1210/en.2002-0214 [Abstract] [Full Text] [PDF]  

GRH-SOMATOSTATIN-GH:

Karen T. Coschigano, Amy N. Holland, Markus E. Riders, Edward O. List, Allan Flyvbjerg, and John J. Kopchick

Deletion, But Not Antagonism, of the Mouse Growth Hormone Receptor Results in Severely Decreased Body Weights, Insulin, and Insulin-Like Growth Factor I Levels and Increased Life Span
Endocrinology 2003 144: 3799-3810, doi:10.1210/en.2003-0374 [Abstract] [Full Text] [PDF]  

Lixin Liu, Carlton E. Dean, and Tom E. Porter

Thyroid Hormones Interact with Glucocorticoids to Affect Somatotroph Abundance in Chicken Embryonic Pituitary Cells in Vitro
Endocrinology 2003 144: 3836-3841, doi:10.1210/en.2003-0160 [Abstract] [Full Text] [PDF]  

Caroline Améen and Jan Oscarsson

Sex Difference in Hepatic Microsomal Triglyceride Transfer Protein Expression Is Determined by the Growth Hormone Secretory Pattern in the Rat
Endocrinology 2003 144: 3914-3921, doi:10.1210/en.2003-0518 [Abstract] [Full Text] [PDF]  

T. M. Badger, M. J. J. Ronis, S. J. Frank, Y. Chen, and L. He

Effects of Chronic Ethanol on Hepatic and Renal CYP2C11 in the Male Rat: Interactions with the Janus-Kinase 2-Signal Transducer and Activators of Transcription Proteins 5b Pathway
Endocrinology 2003 144: 3969-3976, doi:10.1210/en.2002-0163 [Abstract] [Full Text] [PDF]  

Dieter Mesotten, Greet Van den Berghe, Christopher Liddle, Sally Coulter, Fiona McDougall, Robert C. Baxter, and Patric J. D. Delhanty

Growth Hormone Modulation of the Rat Hepatic Bile Transporter System in Endotoxin-Induced Cholestasis
Endocrinology 2003 144: 4008-4017, doi:10.1210/en.2003-0139 [Abstract] [Full Text] [PDF]  

Warren K. Yunker, Sean Smith, Chad Graves, Philip J. Davis, Surajlal Unniappan, Jean E. Rivier, Richard E. Peter, and John P. Chang

Endogenous Hypothalamic Somatostatins Differentially Regulate Growth Hormone Secretion from Goldfish Pituitary Somatotropes in Vitro
Endocrinology 2003 144: 4031-4041, doi:10.1210/en.2003-0439 [Abstract] [Full Text] [PDF]  

GROWTH FACTORS-CYTOKINES-ONCOGENES:

Charles H. Lang, Thomas C. Vary, and Robert A. Frost

Acute in Vivo Elevation of Insulin-Like Growth Factor (IGF) Binding Protein-1 Decreases Plasma Free IGF-I and Muscle Protein Synthesis
Endocrinology 2003 144: 3922-3933, doi:10.1210/en.2002-0192 [Abstract] [Full Text] [PDF]  

Yuji Kasukawa, David J. Baylink, Rongqing Guo, and Subburaman Mohan

Evidence that Sensitivity to Growth Hormone (GH) Is Growth Period and Tissue Type Dependent: Studies in GH-Deficient lit/lit Mice
Endocrinology 2003 144: 3950-3957, doi:10.1210/en.2002-0123 [Abstract] [Full Text] [PDF]  

Suresh Mishra and Liam J. Murphy

Phosphorylation of Insulin-Like Growth Factor (IGF) Binding Protein-3 by Breast Cancer Cell Membranes Enhances IGF-I Binding
Endocrinology 2003 144: 4042-4050, doi:10.1210/en.2003-0089 [Abstract] [Full Text] [PDF]  

Hyun-Ja Jeong, Ho-Jeong Na, Seung-Heon Hong, and Hyung-Min Kim

Inhibition of the Stem Cell Factor-Induced Migration of Mast Cells by Dexamethasone
Endocrinology 2003 144: 4080-4086, doi:10.1210/en.2003-0115 [Abstract] [Full Text] [PDF]  

INSULIN-GLUCAGON-GI PEPTIDES-DIABETES MELLITUS:

Mark J. Holness, Gemma K. Greenwood, Nicholas D. Smith, and Mary C. Sugden

Diabetogenic Impact of Long-Chain -3 Fatty Acids on Pancreatic ß-Cell Function and the Regulation of Endogenous Glucose Production
Endocrinology 2003 144: 3958-3968, doi:10.1210/en.2003-0479 [Abstract] [Full Text] [PDF]  

M. Vincent, Y. Guz, M. Rozenberg, G. Webb, M. Furuta, D. Steiner, and G. Teitelman

Abrogation of Protein Convertase 2 Activity Results in Delayed Islet Cell Differentiation and Maturation, Increased -Cell Proliferation, and Islet Neogenesis
Endocrinology 2003 144: 4061-4069, doi:10.1210/en.2003-0088 [Abstract] [Full Text] [PDF]  

Wissal El-Assaad, Jean Buteau, Marie-Line Peyot, Christopher Nolan, Raphael Roduit, Serge Hardy, Erik Joly, Ghassan Dbaibo, Lawrence Rosenberg, and Marc Prentki

Saturated Fatty Acids Synergize with Elevated Glucose to Cause Pancreatic ß-Cell Death
Endocrinology 2003 144: 4154-4163, doi:10.1210/en.2003-0410 [Abstract] [Full Text] [PDF]  

INTRACELLULAR SIGNAL SYSTEMS:

Eileen L. Whiteman, Janine J. Chen, and Morris J. Birnbaum

Platelet-Derived Growth Factor (PDGF) Stimulates Glucose Transport in 3T3-L1 Adipocytes Overexpressing PDGF Receptor by a Pathway Independent of Insulin Receptor Substrates
Endocrinology 2003 144: 3811-3820, doi:10.1210/en.2003-0480 [Abstract] [Full Text] [PDF]  

Takashi Hirakawa and Mario Ascoli

A Constitutively Active Somatic Mutation of the Human Lutropin Receptor Found in Leydig Cell Tumors Activates the Same Families of G Proteins as Germ Line Mutations Associated with Leydig Cell Hyperplasia
Endocrinology 2003 144: 3872-3878, doi:10.1210/en.2003-0365 [Abstract] [Full Text] [PDF]  

H. Sunny Sun, Kuei-Yang Hsiao, Chih-Chao Hsu, Meng-Hsing Wu, and Shaw-Jenq Tsai

Transactivation of Steroidogenic Acute Regulatory Protein in Human Endometriotic Stromal Cells Is Mediated by the Prostaglandin EP2 Receptor
Endocrinology 2003 144: 3934-3942, doi:10.1210/en.2003-0289 [Abstract] [Full Text] [PDF]  

Nadhim Bayatti, Jürgen Zschocke, and Christian Behl

Brain Region-Specific Neuroprotective Action and Signaling of Corticotropin-Releasing Hormone in Primary Neurons
Endocrinology 2003 144: 4051-4060, doi:10.1210/en.2003-0168 [Abstract] [Full Text] [PDF]  

Toshiyasu Sasaoka, Kosei Kikuchi, Tsutomu Wada, Akira Sato, Hiroyuki Hori, Shihou Murakami, Kazuhito Fukui, Hajime Ishihara, Rina Aota, Ikuko Kimura, and Masashi Kobayashi

Dual Role of Src Homology Domain 2-Containing Inositol Phosphatase 2 in the Regulation of Platelet-Derived Growth Factor and Insulin-Like Growth Factor I Signaling in Rat Vascular Smooth Muscle Cells
Endocrinology 2003 144: 4204-4214, doi:10.1210/en.2003-0190 [Abstract] [Full Text] [PDF]  

NEUROENDOCRINOLOGY:

Rekha Pal and Abhiram Sahu

Leptin Signaling in the Hypothalamus during Chronic Central Leptin Infusion
Endocrinology 2003 144: 3789-3798, doi:10.1210/en.2002-0148 [Abstract] [Full Text] [PDF]  

Anne M. Etgen and Maricedes Acosta-Martinez

Participation of Growth Factor Signal Transduction Pathways in Estradiol Facilitation of Female Reproductive Behavior
Endocrinology 2003 144: 3828-3835, doi:10.1210/en.2003-0157 [Abstract] [Full Text] [PDF]  

Kazuyoshi Ukena, Aya Koda, Kazutoshi Yamamoto, Tetsuya Kobayashi, Eiko Iwakoshi-Ukena, Hiroyuki Minakata, Sakae Kikuyama, and Kazuyoshi Tsutsui

Novel Neuropeptides Related to Frog Growth Hormone-Releasing Peptide: Isolation, Sequence, and Functional Analysis
Endocrinology 2003 144: 3879-3884, doi:10.1210/en.2003-0359 [Abstract] [Full Text] [PDF]  

Tandra R. Chakraborty, Laurie Ng, and Andrea C. Gore

Age-Related Changes in Estrogen Receptor ß in Rat Hypothalamus: A Quantitative Analysis
Endocrinology 2003 144: 4164-4171, doi:10.1210/en.2003-0052 [Abstract] [Full Text] [PDF]  

PTH-CALCITONIN-VITAMIN D-BONE:

Florent Elefteriou, Shu Takeda, Xiuyun Liu, Dawna Armstrong, and Gerard Karsenty

Monosodium Glutamate-Sensitive Hypothalamic Neurons Contribute to the Control of Bone Mass
Endocrinology 2003 144: 3842-3847, doi:10.1210/en.2003-0369 [Abstract] [Full Text] [PDF]  

Yurong Song, Xiaorong Peng, Angela Porta, Hitomi Takanaga, Ji-Bin Peng, Matthias A. Hediger, James C. Fleet, and Sylvia Christakos

Calcium Transporter 1 and Epithelial Calcium Channel Messenger Ribonucleic Acid Are Differentially Regulated by 1,25 Dihydroxyvitamin D₃ in the Intestine and Kidney of Mice
Endocrinology 2003 144: 3885-3894, doi:10.1210/en.2003-0314 [Abstract] [Full Text] [PDF]  

R. Chiusaroli, A. Maier, M. C. Knight, M. Byrne, L. M. Calvi, R. Baron, S. M. Krane, and E. Schipani

Collagenase Cleavage of Type I Collagen Is Essential for Both Basal and Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor-Induced Osteoclast Activation and Has Differential Effects on Discrete Bone Compartments
Endocrinology 2003 144: 4106-4116, doi:10.1210/en.2003-0254 [Abstract] [Full Text] [PDF]  

Yuji Yoshiko, Norihiko Maeda, and Jane E. Aubin

Stanniocalcin 1 Stimulates Osteoblast Differentiation in Rat Calvaria Cell Cultures
Endocrinology 2003 144: 4134-4143, doi:10.1210/en.2003-0130 [Abstract] [Full Text] [PDF]  

RECEPTORS:

Adam J. Pawson, Stuart R. Maudsley, John Lopes, Arieh A. Katz, Yuh-Man Sun, James S. Davidson, and Robert P. Millar

Multiple Determinants for Rapid Agonist-Induced Internalization of a Nonmammalian Gonadotropin-Releasing Hormone Receptor: A Putative Palmitoylation Site and Threonine Doublet within the Carboxyl-Terminal Tail Are Critical
Endocrinology 2003 144: 3860-3871, doi:10.1210/en.2003-0028 [Abstract] [Full Text] [PDF]  

Masayuki Tanaka, Mayumi Nishi, Masafumi Morimoto, Tohru Sugimoto, and Mitsuhiro Kawata

Yellow Fluorescent Protein-Tagged and Cyan Fluorescent Protein-Tagged Imaging Analysis of Glucocorticoid Receptor and Importins in Single Living Cells
Endocrinology 2003 144: 4070-4079, doi:10.1210/en.2003-0282 [Abstract] [Full Text] [PDF]  

RENIN-MINERALOCORTICOIDS-ANF-ADH:

Morag Young and John Funder

Mineralocorticoid Action and Sodium-Hydrogen Exchange: Studies in Experimental Cardiac Fibrosis
Endocrinology 2003 144: 3848-3851, doi:10.1210/en.2003-0039 [Abstract] [Full Text] [PDF]  

Takahiro Hasegawa, Haruna Tanii, Masakazu Suzuki, and Shigeyasu Tanaka

Regulation of Water Absorption in the Frog Skins by Two Vasotocin-Dependent Water-Channel Aquaporins, AQP-h2 and AQP-h3
Endocrinology 2003 144: 4087-4096, doi:10.1210/en.2003-0418 [Abstract] [Full Text] [PDF]  

Faquan Liang, Feng Wang, Sumei Zhang, and David G. Gardner

Peroxisome Proliferator Activated Receptor (PPAR) Agonists Inhibit Hypertrophy of Neonatal Rat Cardiac Myocytes
Endocrinology 2003 144: 4187-4194, doi:10.1210/en.2002-0217 [Abstract] [Full Text] [PDF]  

REPRODUCTION-DEVELOPMENT:

Jeremy J. Buzzard, Nigel G. Wreford, and John R. Morrison

Thyroid Hormone, Retinoic Acid, and Testosterone Suppress Proliferation and Induce Markers of Differentiation in Cultured Rat Sertoli Cells
Endocrinology 2003 144: 3722-3731, doi:10.1210/en.2003-0379 [Abstract] [Full Text] [PDF]  

Denise R. Holsberger, Siwanon Jirawatnotai, Hiroaki Kiyokawa, and Paul S. Cooke

Thyroid Hormone Regulates the Cell Cycle Inhibitor p27^Kip1 in Postnatal Murine Sertoli Cells
Endocrinology 2003 144: 3732-3738, doi:10.1210/en.2003-0389 [Abstract] [Full Text] [PDF]  

Shinobu Yasuo, Miwa Watanabe, Naritoshi Okabayashi, Shizufumi Ebihara, and Takashi Yoshimura

Circadian Clock Genes and Photoperiodism: Comprehensive Analysis of Clock Gene Expression in the Mediobasal Hypothalamus, the Suprachiasmatic Nucleus, and the Pineal Gland of Japanese Quail under Various Light Schedules
Endocrinology 2003 144: 3742-3748, doi:10.1210/en.2003-0435 [Abstract] [Full Text] [PDF] [Supplemental Figure]  

Bridget Sisco, Lora J. Hagemann, Andrew N. Shelling, and Peter L. Pfeffer

Isolation of Genes Differentially Expressed in Dominant and Subordinate Bovine Follicles
Endocrinology 2003 144: 3904-3913, doi:10.1210/en.2003-0485 [Abstract] [Full Text] [PDF]  

Anthony J. Zeleznik, Deeksha Saxena, and Lynda Little-Ihrig

Protein Kinase B Is Obligatory for Follicle-Stimulating Hormone-Induced Granulosa Cell Differentiation
Endocrinology 2003 144: 3985-3994, doi:10.1210/en.2003-0293 [Abstract] [Full Text] [PDF]  

Lydia K. Bachir, Ghislaine Garrel, Anne Lozach, Jean-Noël Laverrière, and Raymond Counis

The Rat Pituitary Promoter of the Neuronal Nitric Oxide Synthase Gene Contains an Sp1-, LIM Homeodomain-Dependent Enhancer and a Distinct Bipartite Gonadotropin-Releasing Hormone-Responsive Region
Endocrinology 2003 144: 3995-4007, doi:10.1210/en.2002-0183 [Abstract] [Full Text] [PDF]  

Kate Lakoski Loveland, Marilyn Bakker, Terri Meehan, Elizabeth Christy, Viktoria von Schönfeldt, Ann Drummond, and David de Kretser

Expression of Bambi Is Widespread in Juvenile and Adult Rat Tissues and Is Regulated in Male Germ Cells
Endocrinology 2003 144: 4180-4186, doi:10.1210/en.2002-0124 [Abstract] [Full Text] [PDF]  

TRH-TSH-THYROID:

Rosa A. Vacca, Loredana Moro, Giovanni Caraccio, Ferruccio Guerrieri, Ersilia Marra, and Margherita Greco

Thyroid Hormone Administration to Hypothyroid Rats Restores the Mitochondrial Membrane Permeability Properties
Endocrinology 2003 144: 3783-3788, doi:10.1210/en.2003-0310 [Abstract] [Full Text] [PDF]  

Chun-Rong Chen, Gregorio D. Chazenbalk, Sandra M. McLachlan, and Basil Rapoport

Evidence that the C Terminus of the A Subunit Suppresses Thyrotropin Receptor Constitutive Activity
Endocrinology 2003 144: 3821-3827, doi:10.1210/en.2003-0430 [Abstract] [Full Text] [PDF]  

D. Fuhrer, M. D. Lewis, F. Alkhafaji, K. Starkey, R. Paschke, D. Wynford-Thomas, M. Eggo, and M. Ludgate

Biological Activity of Activating Thyroid-Stimulating Hormone Receptor Mutants Depends on the Cellular Context
Endocrinology 2003 144: 4018-4030, doi:10.1210/en.2003-0438 [Abstract] [Full Text] [PDF]  

Takanori Esaki, Hideyo Suzuki, Michelle Cook, Kazuaki Shimoji, Sheue-Yann Cheng, Louis Sokoloff, and Jacques Nunez

Functional Activation of Cerebral Metabolism in Mice with Mutated Thyroid Hormone Nuclear Receptors
Endocrinology 2003 144: 4117-4122, doi:10.1210/en.2003-0414 [Abstract] [Full Text] [PDF]  

Yuji Kamiya, Xiao-Yong Zhang, Hao Ying, Yusuhito Kato, Mark C. Willingham, Jianming Xu, Bert W. O’Malley, and Sheue-Yann Cheng

Modulation by Steroid Receptor Coactivator-1 of Target-Tissue Responsiveness in Resistance to Thyroid Hormone
Endocrinology 2003 144: 4144-4153, doi:10.1210/en.2003-0239 [Abstract] [Full Text] [PDF]  

Li Sui and M. E. Gilbert

Pre- and Postnatal Propylthiouracil-Induced Hypothyroidism Impairs Synaptic Transmission and Plasticity in Area CA1 of the Neonatal Rat Hippocampus
Endocrinology 2003 144: 4195-4203, doi:10.1210/en.2003-0395 [Abstract] [Full Text] [PDF]  

RESEARCH RESOURCES:

Endocrine-Related Resources from the National Institutes of Health
Endocrinology 2003 144: 4215-4217 [Full Text] [PDF]  

National Hormone & Peptide Program (NHPP): New Recombinant Hormones, Hypothalamic Peptides, Natural Hormones, New Antisera, & Expanded Hormone Assay Services Available
Endocrinology 2003 144: 4218-4220 [Full Text] [PDF]  

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