NEWS & VIEWS:

Bentley Cheatham

Enough Is Enough: Nutrient Sensors and Insulin Resistance
Endocrinology 2004 145: 2115-2117, doi:10.1210/en.2004-0146 [Full Text]  

Lincoln R. Potter

CNP, Cardiac Natriuretic Peptide?
Endocrinology 2004 145: 2129-2130, doi:10.1210/en.2004-0181 [Full Text]  

CANCER:

Min Tong and Hsin-Hsiung Tai

Synergistic Induction of the Nicotinamide Adenine Dinucleotide-Linked 15-Hydroxyprostaglandin Dehydrogenase by an Androgen and Interleukin-6 or Forskolin in Human Prostate Cancer Cells
Endocrinology 2004 145: 2141-2147; first published January 28 2004 as doi:10.1210/en.2003-1229 [Abstract] [Full Text]  

Virginie Quidville, Nadine Segond, Elisabeth Pidoux, Regis Cohen, Annick Jullienne, and Sylvie Lausson

Tumor Growth Inhibition by Indomethacin in a Mouse Model of Human Medullary Thyroid Cancer: Implication of Cyclooxygenases and 15-Hydroxyprostaglandin Dehydrogenase
Endocrinology 2004 145: 2561-2571; first published January 21 2004 as doi:10.1210/en.2003-0915 [Abstract] [Full Text]  

CRH-ACTH-POMC-ADRENAL:

J. J. Lee, P. Eisenberg, V. Papadopoulos, J. Wang, and E. P. Widmaier

Reversible Changes in Adrenocorticotropin (ACTH)-Induced Adrenocortical Steroidogenesis and Expression of the Peripheral-Type Benzodiazepine Receptor during the ACTH-Insensitive Period in Young Rats
Endocrinology 2004 145: 2165-2173; first published February 12 2004 as doi:10.1210/en.2003-1669 [Abstract] [Full Text]  

Ahmad Pazirandeh, Mikael Jondal, and Sam Okret

Glucocorticoids Delay Age-Associated Thymic Involution through Directly Affecting the Thymocytes
Endocrinology 2004 145: 2392-2401; first published January 21 2004 as doi:10.1210/en.2003-1660 [Abstract] [Full Text]  

Alon Chen, Amy Blount, Joan Vaughan, Bhawanjit Brar, and Wylie Vale

Urocortin II Gene Is Highly Expressed in Mouse Skin and Skeletal Muscle Tissues: Localization, Basal Expression in Corticotropin-Releasing Factor Receptor (CRFR) 1- and CRFR2-Null Mice, and Regulation by Glucocorticoids
Endocrinology 2004 145: 2445-2457; first published January 21 2004 as doi:10.1210/en.2003-1570 [Abstract] [Full Text]  

ENERGY BALANCE/OBESITY:

Susanne E. la Fleur, Susan F. Akana, Sotara L. Manalo, and Mary F. Dallman

Interaction between Corticosterone and Insulin in Obesity: Regulation of Lard Intake and Fat Stores
Endocrinology 2004 145: 2174-2185; first published February 12 2004 as doi:10.1210/en.2003-1359 [Abstract] [Full Text]  

Stephen V. Angeloni, Nicole Glynn, Grazia Ambrosini, Michael J. Garant, J. Dee Higley, Stephen Suomi, and Barbara C. Hansen

Characterization of the Rhesus Monkey Ghrelin Gene and Factors Influencing Ghrelin Gene Expression and Fasting Plasma Levels
Endocrinology 2004 145: 2197-2205; first published January 21 2004 as doi:10.1210/en.2003-1103 [Abstract] [Full Text]  

Cédric Asensio, Philippe Cettour-Rose, Claudia Theander-Carrillo, Françoise Rohner-Jeanrenaud, and Patrick Muzzin

Changes in Glycemia by Leptin Administration or High- Fat Feeding in Rodent Models of Obesity/Type 2 Diabetes Suggest a Link between Resistin Expression and Control of Glucose Homeostasis
Endocrinology 2004 145: 2206-2213; first published February 12 2004 as doi:10.1210/en.2003-1679 [Abstract] [Full Text]  

Kathryn E. Wellen, K. Teoman Uysal, Sarah Wiesbrock, Qing Yang, Hong Chen, and Gökhan S. Hotamisligil

Interaction of Tumor Necrosis Factor-- and Thiazolidinedione-Regulated Pathways in Obesity
Endocrinology 2004 145: 2214-2220; first published February 5 2004 as doi:10.1210/en.2003-1580 [Abstract] [Full Text] [Supplemental Table]  

Feifan Guo, Keren Bakal, Yasuhiko Minokoshi, and Anthony N. Hollenberg

Leptin Signaling Targets the Thyrotropin-Releasing Hormone Gene Promoter in Vivo
Endocrinology 2004 145: 2221-2227; first published February 5 2004 as doi:10.1210/en.2003-1312 [Abstract] [Full Text]  

John N. Fain, Atul K. Madan, M. Lloyd Hiler, Paramjeet Cheema, and Suleiman W. Bahouth

Comparison of the Release of Adipokines by Adipose Tissue, Adipose Tissue Matrix, and Adipocytes from Visceral and Subcutaneous Abdominal Adipose Tissues of Obese Humans
Endocrinology 2004 145: 2273-2282; first published January 15 2004 as doi:10.1210/en.2003-1336 [Abstract] [Full Text]  

So Nagai, Chikara Shimizu, Masaaki Umetsu, Satoshi Taniguchi, Mikiko Endo, Hideaki Miyoshi, Narihito Yoshioka, Mitsumasa Kubo, and Takao Koike

Identification of a Functional Peroxisome Proliferator-Activated Receptor Responsive Element within the Murine Perilipin Gene
Endocrinology 2004 145: 2346-2356; first published January 15 2004 as doi:10.1210/en.2003-1180 [Abstract] [Full Text]  

GENERAL ENDOCRINOLOGY:

Annamaria Morelli, Sandra Filippi, Rosa Mancina, Michaela Luconi, Linda Vignozzi, Mirca Marini, Claudio Orlando, Gabriella Barbara Vannelli, Antonio Aversa, Alessandro Natali, Gianni Forti, Mauro Giorgi, Emmanuele A. Jannini, Fabrizio Ledda, and Mario Maggi

Androgens Regulate Phosphodiesterase Type 5 Expression and Functional Activity in Corpora Cavernosa
Endocrinology 2004 145: 2253-2263; first published February 5 2004 as doi:10.1210/en.2003-1699 [Abstract] [Full Text]  

Graciela Krikun, Gil Mor, Ayesha Alvero, Seth Guller, Frederick Schatz, Eva Sapi, Mizanur Rahman, Rebeca Caze, Mazin Qumsiyeh, and Charles J. Lockwood

A Novel Immortalized Human Endometrial Stromal Cell Line with Normal Progestational Response
Endocrinology 2004 145: 2291-2296; first published January 15 2004 as doi:10.1210/en.2003-1606 [Abstract] [Full Text]  

Tomoko Yoneda, Naozumi Ishimaru, Rieko Arakaki, Masaru Kobayashi, Takashi Izawa, Keiji Moriyama, and Yoshio Hayashi

Estrogen Deficiency Accelerates Murine Autoimmune Arthritis Associated with Receptor Activator of Nuclear Factor-B Ligand-Mediated Osteoclastogenesis
Endocrinology 2004 145: 2384-2391; first published January 15 2004 as doi:10.1210/en.2003-1536 [Abstract] [Full Text]  

Genshin Kuriyama, Susumu Takekoshi, Katsuyoshi Tojo, Yoshikatsu Nakai, Michael J. Kuhar, and R. Yoshiyuki Osamura

Cocaine- and Amphetamine-Regulated Transcript Peptide in the Rat Anterior Pituitary Gland Is Localized in Gonadotrophs and Suppresses Prolactin Secretion
Endocrinology 2004 145: 2542-2550; first published February 5 2004 as doi:10.1210/en.2003-0845 [Abstract] [Full Text]  

GRH-SOMATOSTATIN-GH:

Carola W. E. Meyer, Dirk Korthaus, Wolfgang Jagla, Emmanuelle Cornali, Johannes Grosse, Helmut Fuchs, Martin Klingenspor, Stephanie Roemheld, Matthias Tschöp, Gerhard Heldmaier, Martin Hrabé de Angelis, and Michael Nehls

A Novel Missense Mutation in the Mouse Growth Hormone Gene Causes Semidominant Dwarfism, Hyperghrelinemia, and Obesity
Endocrinology 2004 145: 2531-2541; first published January 15 2004 as doi:10.1210/en.2003-1125 [Abstract] [Full Text] [Supplemental Data]  

GROWTH FACTORS-CYTOKINES-ONCOGENES:

Michael A. Allar and Teresa L. Wood

Expression of the Insulin-Like Growth Factor Binding Proteins during Postnatal Development of the Murine Mammary Gland
Endocrinology 2004 145: 2467-2477; first published January 28 2004 as doi:10.1210/en.2003-1641 [Abstract] [Full Text]  

INSULIN-GLUCAGON-GI PEPTIDES-DIABETES MELLITUS:

Mark Hazel, Robert C. Cooksey, Deborah Jones, Glendon Parker, John L. Neidigh, Bryan Witherbee, Eric A. Gulve, and Donald A. McClain

Activation of the Hexosamine Signaling Pathway in Adipose Tissue Results in Decreased Serum Adiponectin and Skeletal Muscle Insulin Resistance
Endocrinology 2004 145: 2118-2128; first published December 18 2003 as doi:10.1210/en.2003-0812 [Abstract] [Full Text]  

Yuji Uchizono, Masanori Iwase, Udai Nakamura, Nobuhiro Sasaki, Daisuke Goto, and Mitsuo Iida

Tacrolimus Impairment of Insulin Secretion in Isolated Rat Islets Occurs at Multiple Distal Sites in Stimulus-Secretion Coupling
Endocrinology 2004 145: 2264-2272; first published February 12 2004 as doi:10.1210/en.2003-1152 [Abstract] [Full Text]  

INTRACELLULAR SIGNAL SYSTEMS:

David Bonfil, Dana Chuderland, Sarah Kraus, David Shahbazian, Ilan Friedberg, Rony Seger, and Zvi Naor

Extracellular Signal-Regulated Kinase, Jun N-Terminal Kinase, p38, and c-Src Are Involved in Gonadotropin-Releasing Hormone-Stimulated Activity of the Glycoprotein Hormone Follicle-Stimulating Hormone ß-Subunit Promoter
Endocrinology 2004 145: 2228-2244; first published January 21 2004 as doi:10.1210/en.2003-1418 [Abstract] [Full Text]  

Juan R. Tejedo, Gladys M. Cahuana, Remedios Ramírez, Margarida Esbert, Juan Jiménez, Francisco Sobrino, and Francisco J. Bedoya

Nitric Oxide Triggers the Phosphatidylinositol 3-Kinase/Akt Survival Pathway in Insulin-Producing RINm5F Cells by Arousing Src to Activate Insulin Receptor Substrate-1
Endocrinology 2004 145: 2319-2327; first published February 5 2004 as doi:10.1210/en.2003-1489 [Abstract] [Full Text]  

Takeshi Tokudome, Takeshi Horio, Megumu Fukunaga, Hiroyuki Okumura, Jun Hino, Kenji Mori, Fumiki Yoshihara, Shin-Ichi Suga, Yuhei Kawano, Masakazu Kohno, and Kenji Kangawa

Ventricular Nonmyocytes Inhibit Doxorubicin-Induced Myocyte Apoptosis: Involvement of Endogenous Endothelin-1 as a Paracrine Factor
Endocrinology 2004 145: 2458-2466; first published January 21 2004 as doi:10.1210/en.2003-1322 [Abstract] [Full Text]  

NEUROENDOCRINOLOGY:

Jennifer W. Hill, Janice H. Urban, Ming Xu, and Jon E. Levine

Estrogen Induces Neuropeptide Y (NPY) Y1 Receptor Gene Expression and Responsiveness to NPY in Gonadotrope-Enriched Pituitary Cell Cultures
Endocrinology 2004 145: 2283-2290; first published January 15 2004 as doi:10.1210/en.2003-1368 [Abstract] [Full Text]  

Oscar González-Flores, Christian Guerra-Araiza, Marco Cerbón, Ignacio Camacho-Arroyo, and Anne M. Etgen

The 26S Proteasome Participates in the Sequential Inhibition of Estrous Behavior Induced by Progesterone in Rats
Endocrinology 2004 145: 2328-2336; first published February 5 2004 as doi:10.1210/en.2003-1162 [Abstract] [Full Text]  

Miho Watanabe, Yasuo Sakuma, and Masakatsu Kato

High Expression of the R-Type Voltage-Gated Ca²⁺ Channel and Its Involvement in Ca²⁺-Dependent Gonadotropin-Releasing Hormone Release in GT1–7 Cells
Endocrinology 2004 145: 2375-2383; first published January 21 2004 as doi:10.1210/en.2003-1257 [Abstract] [Full Text]  

Klaus Metzeler, Agnes Agoston, and Manfred Gratzl

An Intrinsic -Aminobutyric Acid (GABA)ergic System in the Adrenal Cortex: Findings from Human and Rat Adrenal Glands and the NCI-H295R Cell Line
Endocrinology 2004 145: 2402-2411; first published January 15 2004 as doi:10.1210/en.2003-1413 [Abstract] [Full Text]  

Becky J. Proskocil, Harmanjatinder S. Sekhon, Yibing Jia, Valentina Savchenko, Randy D. Blakely, Jon Lindstrom, and Eliot R. Spindel

Acetylcholine Is an Autocrine or Paracrine Hormone Synthesized and Secreted by Airway Bronchial Epithelial Cells
Endocrinology 2004 145: 2498-2506; first published February 5 2004 as doi:10.1210/en.2003-1728 [Abstract] [Full Text]  

Ryutaro Moriyama, Hiroko Tsukamura, Mika Kinoshita, Hirokatsu Okazaki, Yukio Kato, and Kei-ichiro Maeda

In Vitro Increase in Intracellular Calcium Concentrations Induced by Low or High Extracellular Glucose Levels in Ependymocytes and Serotonergic Neurons of the Rat Lower Brainstem
Endocrinology 2004 145: 2507-2515; first published February 12 2004 as doi:10.1210/en.2003-1191 [Abstract] [Full Text]  

PTH-CALCITONIN-VITAMIN D-BONE:

Feng-Sheng Wang, Ching-Jen Wang, Yeung-Jen Chen, Yu-Ting Huang, Hui-Chen Huang, Per-Rong Chang, Yi-Chih Sun, and Kuender D. Yang

Nitric Oxide Donor Increases Osteoprotegerin Production and Osteoclastogenesis Inhibitory Activity in Bone Marrow Stromal Cells from Ovariectomized Rats
Endocrinology 2004 145: 2148-2156; first published February 12 2004 as doi:10.1210/en.2003-1074 [Abstract] [Full Text]  

Majd Zayzafoon, William E. Gathings, and Jay M. McDonald

Modeled Microgravity Inhibits Osteogenic Differentiation of Human Mesenchymal Stem Cells and Increases Adipogenesis
Endocrinology 2004 145: 2421-2432; first published January 28 2004 as doi:10.1210/en.2003-1156 [Abstract] [Full Text]  

T. Mushtaq, P. Bijman, S. F. Ahmed, and C. Farquharson

Insulin-Like Growth Factor-I Augments Chondrocyte Hypertrophy and Reverses Glucocorticoid-Mediated Growth Retardation in Fetal Mice Metatarsal Cultures
Endocrinology 2004 145: 2478-2486; first published January 28 2004 as doi:10.1210/en.2003-1435 [Abstract] [Full Text]  

RECEPTORS:

Paula M. Gault, Kevin Morgan, Adam J. Pawson, Robert P. Millar, and Gerald A. Lincoln

Sheep Exhibit Novel Variations in the Organization of the Mammalian Type II Gonadotropin-Releasing Hormone Receptor Gene
Endocrinology 2004 145: 2362-2374; first published January 28 2004 as doi:10.1210/en.2003-1625 [Abstract] [Full Text]  

RENIN-MINERALOCORTICOIDS-ANF-ADH:

Takeshi Tokudome, Takeshi Horio, Takeshi Soeki, Kenji Mori, Ichiro Kishimoto, Shin-ichi Suga, Fumiki Yoshihara, Yuhei Kawano, Masakazu Kohno, and Kenji Kangawa

Inhibitory Effect of C-Type Natriuretic Peptide (CNP) on Cultured Cardiac Myocyte Hypertrophy: Interference between CNP and Endothelin-1 Signaling Pathways
Endocrinology 2004 145: 2131-2140; first published January 28 2004 as doi:10.1210/en.2003-1260 [Abstract] [Full Text]  

REPRODUCTION-DEVELOPMENT:

C. Jo Corbin, S. M. Mapes, J. Marcos, C. H. Shackleton, D. Morrow, S. Safe, T. Wise, J. Joe Ford, and A. J. Conley

Paralogues of Porcine Aromatase Cytochrome P450: A Novel Hydroxylase Activity Is Associated with the Survival of a Duplicated Gene
Endocrinology 2004 145: 2157-2164; first published February 12 2004 as doi:10.1210/en.2003-1595 [Abstract] [Full Text]  

Vincenzo Pezzi, Rosa Sirianni, Adele Chimento, Marcello Maggiolini, Sonia Bourguiba, Christelle Delalande, Serge Carreau, Sebastiano Andò, Evan R. Simpson, and Colin D. Clyne

Differential Expression of Steroidogenic Factor-1/Adrenal 4 Binding Protein and Liver Receptor Homolog-1 (LRH-1)/Fetoprotein Transcription Factor in the Rat Testis: LRH-1 as a Potential Regulator of Testicular Aromatase Expression
Endocrinology 2004 145: 2186-2196; first published January 21 2004 as doi:10.1210/en.2003-1366 [Abstract] [Full Text]  

Deok-Soo Son, Katherine F. Roby, and Paul F. Terranova

Tumor Necrosis Factor- Induces Serum Amyloid A3 in Mouse Granulosa Cells
Endocrinology 2004 145: 2245-2252; first published January 28 2004 as doi:10.1210/en.2003-1261 [Abstract] [Full Text]  

M. L. Barreiro, R. Pineda, V. M. Navarro, M. Lopez, J. S. Suominen, L. Pinilla, R. Señaris, J. Toppari, E. Aguilar, C. Diéguez, and M. Tena-Sempere

Orexin 1 Receptor Messenger Ribonucleic Acid Expression and Stimulation of Testosterone Secretion by Orexin-A in Rat Testis
Endocrinology 2004 145: 2297-2306; first published February 5 2004 as doi:10.1210/en.2003-1405 [Abstract] [Full Text]  

Takashi Kajitani, Tetsuya Mizutani, Kazuya Yamada, Takashi Yazawa, Toshio Sekiguchi, Miki Yoshino, Hiroko Kawata, and Kaoru Miyamoto

Cloning and Characterization of Granulosa Cell High-Mobility Group (HMG)-Box Protein-1, a Novel HMG-Box Transcriptional Regulator Strongly Expressed in Rat Ovarian Granulosa Cells
Endocrinology 2004 145: 2307-2318; first published February 5 2004 as doi:10.1210/en.2003-1343 [Abstract] [Full Text]  

Géraldine Bienvenu, Danielle Seurin, Pascale Grellier, Pascal Froment, Marielle Baudrimont, Philippe Monget, Yves Le Bouc, and Sylvie Babajko

Insulin-Like Growth Factor Binding Protein-6 Transgenic Mice: Postnatal Growth, Brain Development, and Reproduction Abnormalities
Endocrinology 2004 145: 2412-2420; first published January 28 2004 as doi:10.1210/en.2003-1196 [Abstract] [Full Text]  

Sirpa J. Hirvonen-Santti, Venkataraman Sriraman, Mikko Anttonen, Saija Savolainen, Jorma J. Palvimo, Markku Heikinheimo, Joanne S. Richards, and Olli A. Jänne

Small Nuclear RING Finger Protein Expression during Gonad Development: Regulation by Gonadotropins and Estrogen in the Postnatal Ovary
Endocrinology 2004 145: 2433-2444; first published January 28 2004 as doi:10.1210/en.2003-1328 [Abstract] [Full Text]  

M. H. Tong, L. K. Christenson, and W.-C. Song

Aberrant Cholesterol Transport and Impaired Steroidogenesis in Leydig Cells Lacking Estrogen Sulfotransferase
Endocrinology 2004 145: 2487-2497; first published January 28 2004 as doi:10.1210/en.2003-1237 [Abstract] [Full Text]  

J. A. Arosh, S. K. Banu, P. Chapdelaine, E. Madore, J. Sirois, and M. A. Fortier

Prostaglandin Biosynthesis, Transport, and Signaling in Corpus Luteum: A Basis for Autoregulation of Luteal Function
Endocrinology 2004 145: 2551-2560; first published January 21 2004 as doi:10.1210/en.2003-1607 [Abstract] [Full Text]  

TRH-TSH-THYROID:

Sandrine M. Dupré, Hajer Guissouma, Frédéric Flamant, Isabelle Seugnet, Thomas S. Scanlan, John D. Baxter, Jacques Samarut, Barbara A. Demeneix, and Nathalie Becker

Both Thyroid Hormone Receptor (TR)ß1 and TRß2 Isoforms Contribute to the Regulation of Hypothalamic Thyrotropin-Releasing Hormone
Endocrinology 2004 145: 2337-2345; first published January 15 2004 as doi:10.1210/en.2003-1209 [Abstract] [Full Text]  

Joshua D. Safer, Tara M. Crawford, and Michael F. Holick

A Role for Thyroid Hormone in Wound Healing through Keratin Gene Expression
Endocrinology 2004 145: 2357-2361; first published January 21 2004 as doi:10.1210/en.2003-1696 [Abstract] [Full Text]  

Lihong Huo, Heike Münzberg, Eduardo A. Nillni, and Christian Bjørbæk

Role of Signal Transducer and Activator of Transcription 3 in Regulation of Hypothalamic trh Gene Expression by Leptin
Endocrinology 2004 145: 2516-2523; first published February 5 2004 as doi:10.1210/en.2003-1242 [Abstract] [Full Text]  

Yu-Shu Li, Naotetsu Kanamoto, Yuji Hataya, Kenji Moriyama, Hitomi Hiratani, Kazuwa Nakao, and Takashi Akamizu

Transgenic Mice Producing Major Histocompatibility Complex Class II Molecules on Thyroid Cells Do Not Develop Apparent Autoimmune Thyroid Diseases
Endocrinology 2004 145: 2524-2530; first published February 5 2004 as doi:10.1210/en.2003-1654 [Abstract] [Full Text]  

ANNOUNCEMENTS:

The Council of the International Federation of Comparative Endocrinological Societies (IFCES)
Endocrinology 2004 145: 2156 [Full Text]  

Request Copyright Permission Online
Endocrinology 2004 145: 2391 [Full Text]  

RESEARCH RESOURCES:

Endocrine-Related Resources from the National Institutes of Health
Endocrinology 2004 145: 2572-2574 [Full Text]  

National Hormone & Peptide Program (NHPP): New Recombinant Hormones, Hypothalamic Peptides, Natural Hormones, New Antisera, & Expanded Hormone Assay Services Available
Endocrinology 2004 145: 2575-2577 [Full Text]  

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