MINIREVIEWS:

Abhiram Sahu

Minireview: A Hypothalamic Role in Energy Balance with Special Emphasis on Leptin
Endocrinology 2004 145: 2613-2620, doi:10.1210/en.2004-0032 [Abstract] [Full Text] [PDF]  

Sebastien G. Bouret and Richard B. Simerly

Minireview: Leptin and Development of Hypothalamic Feeding Circuits
Endocrinology 2004 145: 2621-2626, doi:10.1210/en.2004-0231 [Abstract] [Full Text] [PDF]  

Pawel K. Olszewski and Allen S. Levine

Minireview: Characterization of Influence of Central Nociceptin/Orphanin FQ on Consummatory Behavior
Endocrinology 2004 145: 2627-2632, doi:10.1210/en.2004-0016 [Abstract] [Full Text] [PDF]  

Mary F. Dallman, Susanne E. la Fleur, Norman C. Pecoraro, Francisca Gomez, Hani Houshyar, and Susan F. Akana

Minireview: Glucocorticoids—Food Intake, Abdominal Obesity, and Wealthy Nations in 2004
Endocrinology 2004 145: 2633-2638, doi:10.1210/en.2004-0037 [Abstract] [Full Text] [PDF]  

Susan E. Schonhoff, Maryann Giel-Moloney, and Andrew B. Leiter

Minireview: Development and Differentiation of Gut Endocrine Cells
Endocrinology 2004 145: 2639-2644, doi:10.1210/en.2004-0051 [Abstract] [Full Text] [PDF]  

Asim J. Rashid, Brian F. O’Dowd, and Susan R. George

Minireview: Diversity and Complexity of Signaling through Peptidergic G Protein-Coupled Receptors
Endocrinology 2004 145: 2645-2652, doi:10.1210/en.2004-0052 [Abstract] [Full Text] [PDF]  

P. L. Brubaker and D. J. Drucker

Minireview: Glucagon-Like Peptides Regulate Cell Proliferation and Apoptosis in the Pancreas, Gut, and Central Nervous System
Endocrinology 2004 145: 2653-2659, doi:10.1210/en.2004-0015 [Abstract] [Full Text] [PDF]  

Maralyn R. Druce, Caroline J. Small, and Stephen R. Bloom

Minireview: Gut Peptides Regulating Satiety
Endocrinology 2004 145: 2660-2665, doi:10.1210/en.2004-0089 [Abstract] [Full Text] [PDF]  

NEWS & VIEWS:

Jeffrey E. Pessin

Tipping the Balance on Obesity
Endocrinology 2004 145: 2581, doi:10.1210/en.2004-0377 [Full Text] [PDF]  

Anthony P. Coll, Benjamin G. Challis, and Stephen O’Rahilly

Peptide YY_3–36 and Satiety: Clarity or Confusion?
Endocrinology 2004 145: 2582-2584, doi:10.1210/en.2004-0342 [Full Text] [PDF]  

Alison M. Strack and Robert W. Myers

Modulation of Metabolic Syndrome by Fibroblast Growth Factor 19 (FGF19)?
Endocrinology 2004 145: 2591-2593, doi:10.1210/en.2004-0367 [Full Text] [PDF]  

Michael A. Cowley and Kevin L. Grove

Ghrelin—Satisfying a Hunger for the Mechanism
Endocrinology 2004 145: 2604-2606, doi:10.1210/en.2004-0346 [Full Text] [PDF]  

BRIEF COMMUNICATIONS:

Kristina A. Fenoglio, Kristen L. Brunson, Sarit Avishai-Eliner, Yuncai Chen, and Tallie Z. Baram

Region-Specific Onset of Handling-Induced Changes in Corticotropin-Releasing Factor and Glucocorticoid Receptor Expression
Endocrinology 2004 145: 2702-2706, doi:10.1210/en.2004-0111 [Abstract] [Full Text] [PDF]  

Nicholas M. Morton, Lynne Ramage, and Jonathan R. Seckl

Down-Regulation of Adipose 11ß-Hydroxysteroid Dehydrogenase Type 1 by High-Fat Feeding in Mice: A Potential Adaptive Mechanism Counteracting Metabolic Disease
Endocrinology 2004 145: 2707-2712, doi:10.1210/en.2003-1674 [Abstract] [Full Text] [PDF]  

CANCER:

Fumihiko Furuya, Hiroki Shimura, Hideyo Suzuki, Katsumi Taki, Kazuyasu Ohta, Kazutaka Haraguchi, Toshimasa Onaya, Toyoshi Endo, and Tetsuro Kobayashi

Histone Deacetylase Inhibitors Restore Radioiodide Uptake and Retention in Poorly Differentiated and Anaplastic Thyroid Cancer Cells by Expression of the Sodium/Iodide Symporter Thyroperoxidase and Thyroglobulin
Endocrinology 2004 145: 2865-2875, doi:10.1210/en.2003-1258 [Abstract] [Full Text] [PDF]  

Xinbo Liao, J. Brantley Thrasher, Jeffery Holzbeierlein, Scott Stanley, and Benyi Li

Glycogen Synthase Kinase-3ß Activity Is Required for Androgen-Stimulated Gene Expression in Prostate Cancer
Endocrinology 2004 145: 2941-2949, doi:10.1210/en.2003-1519 [Abstract] [Full Text] [PDF]  

ENERGY BALANCE/OBESITY:

Ilia G. Halatchev, Kate L. J. Ellacott, Wei Fan, and Roger D. Cone

Peptide YY_3–36 Inhibits Food Intake in Mice through a Melanocortin-4 Receptor-Independent Mechanism
Endocrinology 2004 145: 2585-2590, doi:10.1210/en.2003-1754 [Abstract] [Full Text] [PDF]  

Ling Fu, Linu M. John, Sean H. Adams, Xing Xian Yu, Elizabeth Tomlinson, Mark Renz, P. Mickey Williams, Robert Soriano, Racquel Corpuz, Barbara Moffat, Richard Vandlen, Laura Simmons, Jessica Foster, Jean-Philippe Stephan, Siao Ping Tsai, and Timothy A. Stewart

Fibroblast Growth Factor 19 Increases Metabolic Rate and Reverses Dietary and Leptin-Deficient Diabetes
Endocrinology 2004 145: 2594-2603, doi:10.1210/en.2003-1671 [Abstract] [Full Text] [PDF]  

H. Y. Chen, M. E. Trumbauer, A. S. Chen, D. T. Weingarth, J. R. Adams, E. G. Frazier, Z. Shen, D. J. Marsh, S. D. Feighner, X.-M. Guan, Z. Ye, R. P. Nargund, R. G. Smith, L. H. T. Van der Ploeg, A. D. Howard, D. J. MacNeil, and S. Qian

Orexigenic Action of Peripheral Ghrelin Is Mediated by Neuropeptide Y and Agouti-Related Protein
Endocrinology 2004 145: 2607-2612, doi:10.1210/en.2003-1596 [Abstract] [Full Text] [PDF]  

Randip K. Bains, Sara E. Wells, Dave M. Flavell, Keith M. Fairhall, Molly Strom, Paul Le Tissier, and Iain C. A. F. Robinson

Visceral Obesity without Insulin Resistance in Late-Onset Obesity Rats
Endocrinology 2004 145: 2666-2679, doi:10.1210/en.2003-1608 [Abstract] [Full Text] [PDF]  

Jenny Fäldt, Ingrid Wernstedt, Sharyn M. Fitzgerald, Kristina Wallenius, Göran Bergström, and John-Olov Jansson

Reduced Exercise Endurance in Interleukin-6-Deficient Mice
Endocrinology 2004 145: 2680-2686, doi:10.1210/en.2003-1319 [Abstract] [Full Text] [PDF]  

Catherine L. Dakin, Caroline J. Small, Rachel L. Batterham, Nicola M. Neary, Mark A. Cohen, Michael Patterson, Mohammad A. Ghatei, and Stephen R. Bloom

Peripheral Oxyntomodulin Reduces Food Intake and Body Weight Gain in Rats
Endocrinology 2004 145: 2687-2695, doi:10.1210/en.2003-1338 [Abstract] [Full Text] [PDF]  

Carla Schulz, Kerstin Paulus, and Hendrik Lehnert

Central Nervous and Metabolic Effects of Intranasally Applied Leptin
Endocrinology 2004 145: 2696-2701, doi:10.1210/en.2003-1431 [Abstract] [Full Text] [PDF]  

GENERAL ENDOCRINOLOGY:

Ramón Ríos, Susana Fernández-Nocelos, Isabel Carneiro, Víctor M. Arce, and Jesús Devesa

Differential Response to Exogenous and Endogenous Myostatin in Myoblasts Suggests that Myostatin Acts as an Autocrine Factor in Vivo
Endocrinology 2004 145: 2795-2803, doi:10.1210/en.2003-1166 [Abstract] [Full Text] [PDF]  

Shinji Sakamoto, Masahiro Yokoyama, Xianghua Zhang, Kulkarni Prakash, Kaori Nagao, Takashi Hatanaka, Robert H. Getzenberg, and Yoshiyuki Kakehi

Increased Expression of CYR61, an Extracellular Matrix Signaling Protein, in Human Benign Prostatic Hyperplasia and Its Regulation by Lysophosphatidic Acid
Endocrinology 2004 145: 2929-2940, doi:10.1210/en.2003-1350 [Abstract] [Full Text] [PDF]  

GRH-GH-SOMATOSTATIN:

Johanna G. Miquet, Ana I. Sotelo, Andrzej Bartke, and Daniel Turyn

Suppression of Growth Hormone (GH) Janus Tyrosine Kinase 2/Signal Transducer and Activator of Transcription 5 Signaling Pathway in Transgenic Mice Overexpressing Bovine GH
Endocrinology 2004 145: 2824-2832, doi:10.1210/en.2003-1498 [Abstract] [Full Text] [PDF]  

Robin C. C. Ryther, Alex S. Flynt, Bryan D. Harris, John A. Phillips, III, and James G. Patton

GH1 Splicing Is Regulated by Multiple Enhancers Whose Mutation Produces a Dominant-Negative GH Isoform That Can Be Degraded by Allele-Specific Small Interfering RNA (siRNA)
Endocrinology 2004 145: 2988-2996, doi:10.1210/en.2003-1724 [Abstract] [Full Text] [PDF]  

GROWTH FACTORS-CYTOKINES-ONCOGENES:

Wataru Wada, Hiroyuki Kuwano, Yoshihisa Hasegawa, and Itaru Kojima

The Dependence of Transforming Growth Factor-ß-Induced Collagen Production on Autocrine Factor Activin A in Hepatic Stellate Cells
Endocrinology 2004 145: 2753-2759, doi:10.1210/en.2003-1663 [Abstract] [Full Text] [PDF]  

Haitao Zhang, Haiwei Zhang, Laura Lee, and Margot M. Ip

The Liver-Enriched Inhibitory Protein Isoform of CCAAT/Enhancer-Binding Protein ß, But Not Nuclear Factor-B, Mediates the Transcriptional Inhibition of ß-Casein by Tumor Necrosis Factor-
Endocrinology 2004 145: 2833-2844, doi:10.1210/en.2003-1738 [Abstract] [Full Text] [PDF]  

INSULIN-GLUCAGON-GI PEPTIDES-DIABETES MELLITUS:

P. Augstein, P. Heinke, E. Salzsieder, S. Berg, R. Rettig, C. Salzsieder, and L. C. Harrison

Fas Ligand Down-Regulates Cytokine-Induced Fas Receptor Expression on Insulinoma (NIT-1), But Not Islet Cells, from Autoimmune Nonobese Diabetic Mice
Endocrinology 2004 145: 2747-2752, doi:10.1210/en.2003-0754 [Abstract] [Full Text] [PDF]  

Francesco Andreozzi, Cristina D’Alessandris, Massimo Federici, Emanuela Laratta, Silvia Del Guerra, Stefano Del Prato, Piero Marchetti, Renato Lauro, Francesco Perticone, and Giorgio Sesti

Activation of the Hexosamine Pathway Leads to Phosphorylation of Insulin Receptor Substrate-1 on Ser³⁰⁷ and Ser⁶¹² and Impairs the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Insulin Biosynthetic Pathway in RIN Pancreatic ß-Cells
Endocrinology 2004 145: 2845-2857, doi:10.1210/en.2003-0939 [Abstract] [Full Text] [PDF]  

Violeta Stanojevic, Joel F. Habener, and Melissa K. Thomas

Pancreas Duodenum Homeobox-1 Transcriptional Activation Requires Interactions with p300
Endocrinology 2004 145: 2918-2928, doi:10.1210/en.2003-1188 [Abstract] [Full Text] [PDF]  

Rongkun Liu, Tesfahun Desta, Hongbing He, and Dana T. Graves

Diabetes Alters the Response to Bacteria by Enhancing Fibroblast Apoptosis
Endocrinology 2004 145: 2997-3003, doi:10.1210/en.2003-1601 [Abstract] [Full Text] [PDF]  

E. A. Joanette, B. Reusens, E. Arany, S. Thyssen, R. C. Remacle, and D. J. Hill

Low-Protein Diet during Early Life Causes a Reduction in the Frequency of Cells Immunopositive for Nestin and CD34 in Both Pancreatic Ducts and Islets in the Rat
Endocrinology 2004 145: 3004-3013, doi:10.1210/en.2003-0796 [Abstract] [Full Text] [PDF]  

Mariano Ubeda, Daniel M. Kemp, and Joel F. Habener

Glucose-Induced Expression of the Cyclin-Dependent Protein Kinase 5 Activator p35 Involved in Alzheimer’s Disease Regulates Insulin Gene Transcription in Pancreatic ß-Cells
Endocrinology 2004 145: 3023-3031, doi:10.1210/en.2003-1522 [Abstract] [Full Text] [PDF]  

INTRACELLULAR SIGNAL SYSTEMS:

Peter Zahradka, Brenda Litchie, Ben Storie, and Gail Helwer

Transactivation of the Insulin-Like Growth Factor-I Receptor by Angiotensin II Mediates Downstream Signaling from the Angiotensin II Type 1 Receptor to Phosphatidylinositol 3-Kinase
Endocrinology 2004 145: 2978-2987, doi:10.1210/en.2004-0029 [Abstract] [Full Text] [PDF]  

NEUROENDOCRINOLOGY:

Kellie M. Breen, Catherine A. Stackpole, Iain J. Clarke, Andrew V. Pytiak, Alan J. Tilbrook, Elizabeth R. Wagenmaker, Elizabeth A. Young, and Fred J. Karsch

Does the Type II Glucocorticoid Receptor Mediate Cortisol-Induced Suppression in Pituitary Responsiveness to Gonadotropin-Releasing Hormone?
Endocrinology 2004 145: 2739-2746, doi:10.1210/en.2004-0123 [Abstract] [Full Text] [PDF]  

Stuart K. Amateau, Jesse J. Alt, Carolyn L. Stamps, and Margaret M. McCarthy

Brain Estradiol Content in Newborn Rats: Sex Differences, Regional Heterogeneity, and Possible de Novo Synthesis by the Female Telencephalon
Endocrinology 2004 145: 2906-2917, doi:10.1210/en.2003-1363 [Abstract] [Full Text] [PDF]  

Jeffrey S. Davies, David A. Carter, and Timothy Wells

Photic Stimulation Inhibits Growth Hormone Secretion in Rats: A Hypothalamic Mechanism for Transient Entrainment
Endocrinology 2004 145: 2950-2958, doi:10.1210/en.2003-1236 [Abstract] [Full Text] [PDF]  

Robert L. Goodman, Lique M. Coolen, Greg M. Anderson, Steven L. Hardy, Miro Valent, John M. Connors, Maureen E. Fitzgerald, and Michael N. Lehman

Evidence That Dynorphin Plays a Major Role in Mediating Progesterone Negative Feedback on Gonadotropin-Releasing Hormone Neurons in Sheep
Endocrinology 2004 145: 2959-2967, doi:10.1210/en.2003-1305 [Abstract] [Full Text] [PDF]  

PTH-CALCITONIN-VITAMIN D-BONE:

Alexander P. Alimov, M. Chris Langub, Hartmut H. Malluche, Ok-Kyong Park-Sarge, and Nicholas J. Koszewski

Contrasting Mammalian Parathyroid Hormone (PTH) Promoters: Nuclear Factor-Y Binds to a Deoxyribonucleic Acid Element Unique to the Human PTH Promoter and Acts as a Transcriptional Enhancer
Endocrinology 2004 145: 2713-2720, doi:10.1210/en.2003-1763 [Abstract] [Full Text] [PDF]  

Shin-Ichi Hayashi, Motokazu Tsuneto, Takayuki Yamada, Michinari Nose, Miya Yoshino, Leonard D. Shultz, and Hidetoshi Yamazaki

Lipopolysaccharide-Induced Osteoclastogenesis in Src Homology 2-Domain Phosphatase-1-Deficient Viable Motheaten Mice
Endocrinology 2004 145: 2721-2729, doi:10.1210/en.2004-0172 [Abstract] [Full Text] [PDF]  

W. Bruce Sneddon, Clara E. Magyar, Gordon E. Willick, Colin A. Syme, Ferruccio Galbiati, Alessandro Bisello, and Peter A. Friedman

Ligand-Selective Dissociation of Activation and Internalization of the Parathyroid Hormone (PTH) Receptor: Conditional Efficacy of PTH Peptide Fragments
Endocrinology 2004 145: 2815-2823, doi:10.1210/en.2003-1185 [Abstract] [Full Text] [PDF]  

RECEPTORS:

Houng-Wei Tsai, John A. Katzenellenbogen, Benita S. Katzenellenbogen, and Margaret A. Shupnik

Protein Kinase A Activation of Estrogen Receptor Transcription Does Not Require Proteasome Activity and Protects the Receptor from Ligand-Mediated Degradation
Endocrinology 2004 145: 2730-2738, doi:10.1210/en.2003-1470 [Abstract] [Full Text] [PDF]  

Chung-hsuan Shih, Shen-Liang Chen, Chun-Che Yen, Ya-Hui Huang, Chi-de Chen, Yun-Shien Lee, and Kwang-huei Lin

Thyroid Hormone Receptor-Dependent Transcriptional Regulation of Fibrinogen and Coagulation Proteins
Endocrinology 2004 145: 2804-2814, doi:10.1210/en.2003-1372 [Abstract] [Full Text] [PDF]  

Maithé Corbani, Christophe Gonindard, and Jean-Claude Meunier

Ligand-Regulated Internalization of the Opioid Receptor-Like 1: A Confocal Study
Endocrinology 2004 145: 2876-2885, doi:10.1210/en.2004-0062 [Abstract] [Full Text] [PDF]  

Hyunjung J. Lim, Irene Moon, and Kyuyong Han

Transcriptional Cofactors Exhibit Differential Preference toward Peroxisome Proliferator-Activated Receptors and in Uterine Cells
Endocrinology 2004 145: 2886-2895, doi:10.1210/en.2004-0011 [Abstract] [Full Text] [PDF]  

M. B. Hawkins and P. Thomas

The Unusual Binding Properties of the Third Distinct Teleost Estrogen Receptor Subtype ERßa Are Accompanied by Highly Conserved Amino Acid Changes in the Ligand Binding Domain
Endocrinology 2004 145: 2968-2977, doi:10.1210/en.2003-0806 [Abstract] [Full Text] [PDF]  

REPRODUCTION-DEVELOPMENT:

Gongqiao Zhang and Johannes D. Veldhuis

Requirement for Proximal Putative Sp1 and AP-2 cis-Deoxyribonucleic Acid Elements in Mediating Basal and Luteinizing Hormone- and Insulin-Dependent in Vitro Transcriptional Activation of the CYP17 Gene in Porcine Theca Cells
Endocrinology 2004 145: 2760-2766, doi:10.1210/en.2003-1545 [Abstract] [Full Text] [PDF]  

V. Matagne, G. Rasier, M.-C. Lebrethon, A. Gérard, and J.-P. Bourguignon

Estradiol Stimulation of Pulsatile Gonadotropin-Releasing Hormone Secretion in Vitro: Correlation with Perinatal Exposure to Sex Steroids and Induction of Sexual Precocity in Vivo
Endocrinology 2004 145: 2775-2783, doi:10.1210/en.2003-1259 [Abstract] [Full Text] [PDF]  

J. L. H. Ireland, F. Jimenez-Krassel, M. E. Winn, D. S. Burns, and J. J. Ireland

Evidence for Autocrine or Paracrine Roles of ₂-Macroglobulin in Regulation of Estradiol Production by Granulosa Cells and Development of Dominant Follicles
Endocrinology 2004 145: 2784-2794, doi:10.1210/en.2003-1407 [Abstract] [Full Text] [PDF]  

Antonio Gonzalez-Bulnes, Carlos J. H. Souza, Bruce K. Campbell, and David T. Baird

Effect of Ageing on Hormone Secretion and Follicular Dynamics in Sheep with and without the Booroola Gene
Endocrinology 2004 145: 2858-2864, doi:10.1210/en.2003-1722 [Abstract] [Full Text] [PDF]  

James Greenaway, Kristin Connor, Hanne G. Pedersen, Brenda L. Coomber, Jonathan LaMarre, and Jim Petrik

Vascular Endothelial Growth Factor and Its Receptor, Flk-1/KDR, Are Cytoprotective in the Extravascular Compartment of the Ovarian Follicle
Endocrinology 2004 145: 2896-2905, doi:10.1210/en.2003-1620 [Abstract] [Full Text] [PDF]  

J. J. Peluso, A. Pappalardo, G. Fernandez, and C. A. Wu

Involvement of an Unnamed Protein, RDA288, in the Mechanism through which Progesterone Mediates Its Antiapoptotic Action in Spontaneously Immortalized Granulosa Cells
Endocrinology 2004 145: 3014-3022, doi:10.1210/en.2004-0067 [Abstract] [Full Text] [PDF]  

TRH-TSH-THYROID:

Eric S. Bachman, Thomas G. Hampton, Harveen Dhillon, Ivo Amende, JuFeng Wang, James P. Morgan, and Anthony N. Hollenberg

The Metabolic and Cardiovascular Effects of Hyperthyroidism Are Largely Independent of ß-Adrenergic Stimulation
Endocrinology 2004 145: 2767-2774, doi:10.1210/en.2003-1670 [Abstract] [Full Text] [PDF]  

RESEARCH RESOURCES:

Endocrine-Related Resources from the National Institutes of Health
Endocrinology 2004 145: 3042-3044 [Full Text] [PDF]  

National Hormone and Peptide Program—NIDDK: Peptide Hormones, Subunits, Antisera & Other Reagents Available
Endocrinology 2004 145: 3045-3047 [Full Text] [PDF]  

THE ENDOCRINE SOCIETY:

THE ENDOCRINE SOCIETY ETHICS ADVISORY COMMITTEE: Ethical Aspects of Conflicts of Interests, October 2003
Endocrinology 2004 145: 3032-3041 [Full Text] [PDF]  

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