MINIREVIEWS:

Nadir R. Farid and Mariusz W. Szkudlinski

Minireview: Structural and Functional Evolution of the Thyrotropin Receptor
Endocrinology 2004 145: 4048-4057, doi:10.1210/en.2004-0437 [Abstract] [Full Text] [PDF]  

Rosalind S. Brown

Minireview: Developmental Regulation of Thyrotropin Receptor Gene Expression in the Fetal and Newborn Thyroid
Endocrinology 2004 145: 4058-4061, doi:10.1210/en.2004-0458 [Abstract] [Full Text] [PDF]  

Mario De Felice, Maria Pia Postiglione, and Roberto Di Lauro

Minireview: Thyrotropin Receptor Signaling in Development and Differentiation of the Thyroid Gland: Insights from Mouse Models and Human Diseases
Endocrinology 2004 145: 4062-4067, doi:10.1210/en.2004-0501 [Full Text] [PDF]  

NEWS & VIEWS:

Dirk G. de Rooij and Maaike P. A. van Bragt

Leydig Cells: Testicular Side Population Harbors Transplantable Leydig Stem Cells
Endocrinology 2004 145: 4009-4010, doi:10.1210/en.2004-0578 [Full Text] [PDF]  

Andrea C. Gore

Gonadotropin-Releasing Hormone Neurons: Multiple Inputs, Multiple Outputs
Endocrinology 2004 145: 4016-4017, doi:10.1210/en.2004-0855 [Full Text] [PDF]  

Thierry Alquier and Barbara B. Kahn

Peripheral Signals Set the Tone for Central Regulation of Metabolism
Endocrinology 2004 145: 4022-4024, doi:10.1210/en.2004-0861 [Full Text] [PDF]  

Douglas Forrest

The Developing Brain and Maternal Thyroid Hormone: Finding the Links
Endocrinology 2004 145: 4034-4036, doi:10.1210/en.2004-0603 [Full Text] [PDF]  

BRIEF COMMUNICATIONS:

Kirk C. Lo, Zhenmin Lei, Ch. Venkateswara Rao, Josie Beck, and Dolores J. Lamb

De Novo Testosterone Production in Luteinizing Hormone Receptor Knockout Mice after Transplantation of Leydig Stem Cells
Endocrinology 2004 145: 4011-4015, doi:10.1210/en.2003-1729 [Abstract] [Full Text] [PDF]  

Erik Hrabovszky, Gergely F. Turi, Imre Kalló, and Zsolt Liposits

Expression of Vesicular Glutamate Transporter-2 in Gonadotropin-Releasing Hormone Neurons of the Adult Male Rat
Endocrinology 2004 145: 4018-4021, doi:10.1210/en.2004-0589 [Abstract] [Full Text] [PDF]  

Jennifer Slone-Wilcoxon and Eva E. Redei

Maternal-Fetal Glucocorticoid Milieu Programs Hypothalamic-Pituitary-Thyroid Function of Adult Offspring
Endocrinology 2004 145: 4068-4072, doi:10.1210/en.2004-0473 [Abstract] [Full Text] [PDF]  

M. L. Gottsch, M. J. Cunningham, J. T. Smith, S. M. Popa, B. V. Acohido, W. F. Crowley, S. Seminara, D. K. Clifton, and R. A. Steiner

A Role for Kisspeptins in the Regulation of Gonadotropin Secretion in the Mouse
Endocrinology 2004 145: 4073-4077, doi:10.1210/en.2004-0431 [Abstract] [Full Text] [PDF]  

P. E. MacDonald, J. W. Joseph, D. Yau, J. Diao, Z. Asghar, F. Dai, G. Y. Oudit, M. M. Patel, P. H. Backx, and M. B. Wheeler

Impaired Glucose-Stimulated Insulin Secretion, Enhanced Intraperitoneal Insulin Tolerance, and Increased ß-Cell Mass in Mice Lacking the p110 Isoform of Phosphoinositide 3-Kinase
Endocrinology 2004 145: 4078-4083, doi:10.1210/en.2004-0028 [Abstract] [Full Text] [PDF]  

CANCER:

Jacob Tfelt-Hansen, Shozo Yano, Sanghamitra Bandyopadhyay, Rona Carroll, Edward M. Brown, and Naibedya Chattopadhyay

Expression of Pituitary Tumor Transforming Gene (PTTG) and Its Binding Protein in Human Astrocytes and Astrocytoma Cells: Function and Regulation of PTTG in U87 Astrocytoma Cells
Endocrinology 2004 145: 4222-4231, doi:10.1210/en.2003-1661 [Abstract] [Full Text] [PDF]  

CRH-ACTH-POMC-ADRENAL:

Koustav Mukherjee, Anna Knisely, and Lauren Jacobson

Partial Glucocorticoid Agonist-Like Effects of Imipramine on Hypothalamic-Pituitary-Adrenocortical Activity, Thymus Weight, and Hippocampal Glucocorticoid Receptors in Male C57BL/6 Mice
Endocrinology 2004 145: 4185-4191, doi:10.1210/en.2004-0147 [Abstract] [Full Text] [PDF]  

Michael Thomas, Michelle Keramidas, Emmanuelle Monchaux, and Jean-Jacques Feige

Dual Hormonal Regulation of Endocrine Tissue Mass and Vasculature by Adrenocorticotropin in the Adrenal Cortex
Endocrinology 2004 145: 4320-4329, doi:10.1210/en.2004-0179 [Abstract] [Full Text] [PDF]  

ENERGY BALANCE/OBESITY:

Naohiko Ueno, Michael G. Dube, Akio Inui, Pushpa S. Kalra, and Satya P. Kalra

Leptin Modulates Orexigenic Effects of Ghrelin and Attenuates Adiponectin and Insulin Levels and Selectively the Dark-Phase Feeding as Revealed by Central Leptin Gene Therapy
Endocrinology 2004 145: 4176-4184, doi:10.1210/en.2004-0262 [Abstract] [Full Text] [PDF]  

Pilar Yubero, Elayne Hondares, M. Carmen Carmona, Meritxell Rossell, Frank J. Gonzalez, Roser Iglesias, Marta Giralt, and Francesc Villarroya

The Developmental Regulation of Peroxisome Proliferator-Activated Receptor- Coactivator-1 Expression in the Liver Is Partially Dissociated from the Control of Gluconeogenesis and Lipid Catabolism
Endocrinology 2004 145: 4268-4277, doi:10.1210/en.2004-0099 [Abstract] [Full Text] [PDF]  

GENERAL ENDOCRINOLOGY:

Yuki Tajika, Toshiyuki Matsuzaki, Takeshi Suzuki, Takeo Aoki, Haruo Hagiwara, Michio Kuwahara, Sei Sasaki, and Kuniaki Takata

Aquaporin-2 Is Retrieved to the Apical Storage Compartment via Early Endosomes and Phosphatidylinositol 3-Kinase-Dependent Pathway
Endocrinology 2004 145: 4375-4383, doi:10.1210/en.2004-0073 [Abstract] [Full Text] [PDF]  

Vesna Cingel-Ristic, Johan W. van Neck, Jan Frystyk, Stenvert L. S. Drop, and Allan Flyvbjerg

Administration of Human Insulin-Like Growth Factor-Binding Protein-1 Increases Circulating Levels of Growth Hormone in Mice
Endocrinology 2004 145: 4401-4407, doi:10.1210/en.2003-1742 [Abstract] [Full Text] [PDF]  

GRH-GH-SOMATOSTATIN:

Maria Alba and Roberto Salvatori

A Mouse with Targeted Ablation of the Growth Hormone-Releasing Hormone Gene: A New Model of Isolated Growth Hormone Deficiency
Endocrinology 2004 145: 4134-4143, doi:10.1210/en.2004-0119 [Abstract] [Full Text] [PDF]  

Naotetsu Kanamoto, Takashi Akamizu, Tetsuya Tagami, Yuji Hataya, Kenji Moriyama, Kazuhiko Takaya, Hiroshi Hosoda, Masayasu Kojima, Kenji Kangawa, and Kazuwa Nakao

Genomic Structure and Characterization of the 5'-Flanking Region of the Human Ghrelin Gene
Endocrinology 2004 145: 4144-4153, doi:10.1210/en.2003-1718 [Abstract] [Full Text] [PDF]  

GROWTH FACTORS-CYTOKINES-ONCOGENES:

Chrishan S. Samuel, Elaine N. Unemori, Ishanee Mookerjee, Ross A. D. Bathgate, Sharon L. Layfield, John Mak, Geoffrey W. Tregear, and Xiao-Jun Du

Relaxin Modulates Cardiac Fibroblast Proliferation, Differentiation, and Collagen Production and Reverses Cardiac Fibrosis in Vivo
Endocrinology 2004 145: 4125-4133, doi:10.1210/en.2004-0209 [Abstract] [Full Text] [PDF]  

Amantha Thathiah, Melissa Brayman, Neeraja Dharmaraj, JoAnne J. Julian, Errin L. Lagow, and Daniel D. Carson

Tumor Necrosis Factor Stimulates MUC1 Synthesis and Ectodomain Release in a Human Uterine Epithelial Cell Line
Endocrinology 2004 145: 4192-4203, doi:10.1210/en.2004-0399 [Abstract] [Full Text] [PDF]  

Naoko Ozawa, Masayoshi Shichiri, Nozomi Fukai, Takanobu Yoshimoto, and Yukio Hirata

Regulation of Adrenomedullin Gene Transcription and Degradation by the c-myc Gene
Endocrinology 2004 145: 4244-4250, doi:10.1210/en.2003-0402 [Abstract] [Full Text] [PDF]  

Masaya Takeda, Fumio Otsuka, Kazufumi Nakamura, Kenichi Inagaki, Jiro Suzuki, Daiji Miura, Hideki Fujio, Hiromi Matsubara, Hiroshi Date, Tohru Ohe, and Hirofumi Makino

Characterization of the Bone Morphogenetic Protein (BMP) System in Human Pulmonary Arterial Smooth Muscle Cells Isolated from a Sporadic Case of Primary Pulmonary Hypertension: Roles of BMP Type IB Receptor (Activin Receptor-Like Kinase-6) in the Mitotic Action
Endocrinology 2004 145: 4344-4354, doi:10.1210/en.2004-0234 [Abstract] [Full Text] [PDF]  

Rossana Mineo, Angela Costantino, Franco Frasca, Laura Sciacca, Simona Russo, Riccardo Vigneri, and Antonino Belfiore

Activation of the Hepatocyte Growth Factor (HGF)-Met System in Papillary Thyroid Cancer: Biological Effects of HGF in Thyroid Cancer Cells Depend on Met Expression Levels
Endocrinology 2004 145: 4355-4365, doi:10.1210/en.2003-1762 [Abstract] [Full Text] [PDF]  

INSULIN-GLUCAGON-GI PEPTIDES-DIABETES MELLITUS:

Christophe Perrin, Claude Knauf, and Rémy Burcelin

Intracerebroventricular Infusion of Glucose, Insulin, and the Adenosine Monophosphate-Activated Kinase Activator, 5-Aminoimidazole-4-Carboxamide-1-ß-D-Ribofuranoside, Controls Muscle Glycogen Synthesis
Endocrinology 2004 145: 4025-4033, doi:10.1210/en.2004-0270 [Abstract] [Full Text] [PDF]  

Min Chen, Martin Haluzik, Nicole J. Wolf, Javier Lorenzo, Kelly R. Dietz, Marc L. Reitman, and Lee S. Weinstein

Increased Insulin Sensitivity in Paternal Gnas Knockout Mice Is Associated with Increased Lipid Clearance
Endocrinology 2004 145: 4094-4102, doi:10.1210/en.2004-0038 [Abstract] [Full Text] [PDF]  

T. Clark Brelje, Laurence E. Stout, Nicholas V. Bhagroo, and Robert L. Sorenson

Distinctive Roles for Prolactin and Growth Hormone in the Activation of Signal Transducer and Activator of Transcription 5 in Pancreatic Islets of Langerhans
Endocrinology 2004 145: 4162-4175, doi:10.1210/en.2004-0201 [Abstract] [Full Text] [PDF]  

Li Li, Asheebo Rojas, Jianping Wu, and Chun Jiang

Disruption of Glucose Sensing and Insulin Secretion by Ribozyme Kir6.2-Gene Targeting in Insulin-Secreting Cells
Endocrinology 2004 145: 4408-4414, doi:10.1210/en.2004-0285 [Abstract] [Full Text] [PDF]  

INTRACELLULAR SIGNAL SYSTEMS:

Marc G. Jeschke, Dagmar Klein, Ulrich Bolder, and Ralf Einspanier

Insulin Attenuates the Systemic Inflammatory Response in Endotoxemic Rats
Endocrinology 2004 145: 4084-4093, doi:10.1210/en.2004-0592 [Abstract] [Full Text] [PDF]  

Usha Sivaprasad, Jodie Fleming, Poonam S. Verma, Kelly A. Hogan, Gwenaëlle Desury, and Wendie S. Cohick

Stimulation of Insulin-Like Growth Factor (IGF) Binding Protein-3 Synthesis by IGF-I and Transforming Growth Factor- Is Mediated by Both Phosphatidylinositol-3 Kinase and Mitogen-Activated Protein Kinase Pathways in Mammary Epithelial Cells
Endocrinology 2004 145: 4213-4221, doi:10.1210/en.2003-1377 [Abstract] [Full Text] [PDF]  

Tsugumichi Saito, Shuichi Okada, Kihachi Ohshima, Eijiro Yamada, Minoru Sato, Yutaka Uehara, Hiroyuki Shimizu, Jeffrey E. Pessin, and Masatomo Mori

Differential Activation of Epidermal Growth Factor (EGF) Receptor Downstream Signaling Pathways by Betacellulin and EGF
Endocrinology 2004 145: 4232-4243, doi:10.1210/en.2004-0401 [Abstract] [Full Text] [PDF]  

NEUROENDOCRINOLOGY:

V. C. Russo, S. Metaxas, K. Kobayashi, M. Harris, and G. A. Werther

Antiapoptotic Effects of Leptin in Human Neuroblastoma Cells
Endocrinology 2004 145: 4103-4112, doi:10.1210/en.2003-1767 [Abstract] [Full Text] [PDF]  

A. Vicentic, G. Dominguez, R. G. Hunter, K. Philpot, M. Wilson, and M. J. Kuhar

Cocaine- and Amphetamine-Regulated Transcript Peptide Levels in Blood Exhibit a Diurnal Rhythm: Regulation by Glucocorticoids
Endocrinology 2004 145: 4119-4124, doi:10.1210/en.2003-1648 [Abstract] [Full Text] [PDF]  

Neil J. MacLusky, Tibor Hajszan, and Csaba Leranth

Effects of Dehydroepiandrosterone and Flutamide on Hippocampal CA1 Spine Synapse Density in Male and Female Rats: Implications for the Role of Androgens in Maintenance of Hippocampal Structure
Endocrinology 2004 145: 4154-4161, doi:10.1210/en.2004-0477 [Abstract] [Full Text] [PDF]  

Geoffrey A. Head, Varuni R. Obeyesekere, Margaret E. Jones, Evan R. Simpson, and Zygmunt S. Krozowski

Aromatase-Deficient (ArKO) Mice Have Reduced Blood Pressure and Baroreflex Sensitivity
Endocrinology 2004 145: 4286-4291, doi:10.1210/en.2004-0421 [Abstract] [Full Text] [PDF]  

Gretchen N. Neigh, Stephanie L. Bowers, Leah M. Pyter, Michelle L. Gatien, and Randy J. Nelson

Pyruvate Prevents Restraint-Induced Immunosuppression via Alterations in Glucocorticoid Responses
Endocrinology 2004 145: 4309-4319, doi:10.1210/en.2003-1748 [Abstract] [Full Text] [PDF]  

Subrina Jesmin, Hiroko Togashi, Ichiro Sakuma, Chishimba N. Mowa, Ken-Ichi Ueno, Taku Yamaguchi, Mitsuhiro Yoshioka, and Akira Kitabatake

Gonadal Hormones and Frontocortical Expression of Vascular Endothelial Growth Factor in Male Stroke-Prone, Spontaneously Hypertensive Rats, a Model for Attention-Deficit/Hyperactivity Disorder
Endocrinology 2004 145: 4330-4343, doi:10.1210/en.2004-0487 [Abstract] [Full Text] [PDF]  

Annabelle Reaux-Le Goazigo, Anne Morinville, Arlette Burlet, Catherine Llorens-Cortes, and Alain Beaudet

Dehydration-Induced Cross-Regulation of Apelin and Vasopressin Immunoreactivity Levels in Magnocellular Hypothalamic Neurons
Endocrinology 2004 145: 4392-4400, doi:10.1210/en.2004-0384 [Abstract] [Full Text] [PDF]  

PTH-CALCITONIN-VITAMIN D-BONE:

Jillian Cornish, Karen E. Callon, Dorit Naot, Kate P. Palmano, Tatjana Banovic, Usha Bava, Maureen Watson, Jian-Ming Lin, P. C. Tong, Qi Chen, Vincent A. Chan, Helen E. Reid, Nick Fazzalari, Heather M. Baker, Edward N. Baker, Neill W. Haggarty, Andrew B. Grey, and Ian R. Reid

Lactoferrin Is a Potent Regulator of Bone Cell Activity and Increases Bone Formation in Vivo
Endocrinology 2004 145: 4366-4374, doi:10.1210/en.2003-1307 [Abstract] [Full Text] [PDF]  

REPRODUCTION-DEVELOPMENT:

Hirotaka Nishi, Toshihide Nakada, Mitsuyasu Hokamura, Yumi Osakabe, Osamu Itokazu, L. Eric Huang, and Keiichi Isaka

Hypoxia-Inducible Factor-1 Transactivates Transforming Growth Factor-ß3 in Trophoblast
Endocrinology 2004 145: 4113-4118, doi:10.1210/en.2003-1639 [Abstract] [Full Text] [PDF]  

Mark Paciga, Gabriel E. DiMattia, and Graham F. Wagner

Regulation of Luteal Cell Big Stanniocalcin Production and Secretion
Endocrinology 2004 145: 4204-4212, doi:10.1210/en.2003-1613 [Abstract] [Full Text] [PDF]  

Takashi Yamamura, Kanjun Hirunagi, Shizufumi Ebihara, and Takashi Yoshimura

Seasonal Morphological Changes in the Neuro-Glial Interaction between Gonadotropin-Releasing Hormone Nerve Terminals and Glial Endfeet in Japanese Quail
Endocrinology 2004 145: 4264-4267, doi:10.1210/en.2004-0366 [Abstract] [Full Text] [PDF]  

Frank H. Bloomfield, Mark H. Oliver, Paul Hawkins, Alison C. Holloway, Melanie Campbell, Peter D. Gluckman, Jane E. Harding, and John R. G. Challis

Periconceptional Undernutrition in Sheep Accelerates Maturation of the Fetal Hypothalamic-Pituitary-Adrenal Axis in Late Gestation
Endocrinology 2004 145: 4278-4285, doi:10.1210/en.2004-0424 [Abstract] [Full Text] [PDF]  

Darren C. Tomlinson, Sarah H. Freestone, O. Cathal Grace, and Axel A. Thomson

Differential Effects of Transforming Growth Factor-ß1 on Cellular Proliferation in the Developing Prostate
Endocrinology 2004 145: 4292-4300, doi:10.1210/en.2004-0526 [Abstract] [Full Text] [PDF]  

TRH-TSH-THYROID:

Eva Ausó, Rosalía Lavado-Autric, Estela Cuevas, Francisco Escobar del Rey, Gabriella Morreale de Escobar, and Pere Berbel

A Moderate and Transient Deficiency of Maternal Thyroid Function at the Beginning of Fetal Neocorticogenesis Alters Neuronal Migration
Endocrinology 2004 145: 4037-4047, doi:10.1210/en.2004-0274 [Abstract] [Full Text] [PDF]  

Frank W. J. S. Wassen, Willem Klootwijk, Ellen Kaptein, Dirk J. Duncker, Theo J. Visser, and George G. J. M. Kuiper

Characteristics and Thyroid State-Dependent Regulation of Iodothyronine Deiodinases in Pigs
Endocrinology 2004 145: 4251-4263, doi:10.1210/en.2004-0356 [Abstract] [Full Text] [PDF]  

Akio Yoshida, Ichiro Hisatome, Shinichi Taniguchi, Norihiro Sasaki, Yasutaka Yamamoto, Junichiro Miake, Hiroko Fukui, Hideki Shimizu, Tomohisa Okamura, Tsuyoshi Okura, Osamu Igawa, Chiaki Shigemasa, Eric D. Green, Leonard D. Kohn, and Koichi Suzuki

Mechanism of Iodide/Chloride Exchange by Pendrin
Endocrinology 2004 145: 4301-4308, doi:10.1210/en.2004-0048 [Abstract] [Full Text] [PDF]  

Kimio Tohyama, Hiroyuki Kusuhara, and Yuichi Sugiyama

Involvement of Multispecific Organic Anion Transporter, Oatp14 (Slc21a14), in the Transport of Thyroxine across the Blood-Brain Barrier
Endocrinology 2004 145: 4384-4391, doi:10.1210/en.2004-0058 [Abstract] [Full Text] [PDF]  

ANNOUNCEMENTS:

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RESEARCH RESOURCES:

Endocrine-Related Resources from the National Institutes of Health
Endocrinology 2004 145: 4415-4418 [Full Text] [PDF]  

National Hormone & Peptide Program (NHPP): New Recombinant Hormones, Hypothalamic Peptides, Natural Hormones, New Antisera, & Expanded Hormone Assay Services Available
Endocrinology 2004 145: 4419-4421 [Full Text] [PDF]  

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