NEWS & VIEWS:

Matthew Hickey

Bioengineering Obesity: The Skinny on Leptin Delivery
Endocrinology 2005 146: 4165-4166, doi:10.1210/en.2005-0835 [Full Text] [PDF]  

Nira Ben-Jonathan

Dopamine and Transforming Growth Factor-ß1: An Odd Couple in Growth Inhibition of the Lactotrophs
Endocrinology 2005 146: 4177-4178, doi:10.1210/en.2005-0893 [Full Text] [PDF]  

Leonard D. Kohn, Brian Wallace, Frank Schwartz, and Kelly McCall

Is Type 2 Diabetes an Autoimmune-Inflammatory Disorder of the Innate Immune System?
Endocrinology 2005 146: 4189-4191, doi:10.1210/en.2005-0920 [Full Text] [PDF]  

Barry R. Zirkin

Cyclooxygenase-2 and Reduced Steroidogenesis in the Aging Male
Endocrinology 2005 146: 4200-4201, doi:10.1210/en.2005-0977 [Full Text] [PDF]  

Martin G. Myers, Jr., Mary Elizabeth Patti, and Rebecca L. Leshan

Hitting the Target: Leptin and Perinatal Nutrition in the Predisposition to Obesity
Endocrinology 2005 146: 4209-4210, doi:10.1210/en.2005-0971 [Full Text] [PDF]  

BRIEF COMMUNICATIONS:

Cláudio T. De Souza, Eliana P. Araujo, Silvana Bordin, Rika Ashimine, Ricardo L. Zollner, Antonio C. Boschero, Mário J. A. Saad, and Lício A. Velloso

Consumption of a Fat-Rich Diet Activates a Proinflammatory Response and Induces Insulin Resistance in the Hypothalamus
Endocrinology 2005 146: 4192-4199, doi:10.1210/en.2004-1520 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Takanori Ida, Kenji Mori, Mikiya Miyazato, Yutaka Egi, Shinsuke Abe, Keiko Nakahara, Masugi Nishihara, Kenji Kangawa, and Noboru Murakami

Neuromedin S Is a Novel Anorexigenic Hormone
Endocrinology 2005 146: 4217-4223, doi:10.1210/en.2005-0107 [Abstract] [Full Text] [PDF]  

CANCER:

Sharda Vyas, Yayesh Asmerom, and Daisy D. De León

Resveratrol Regulates Insulin-Like Growth Factor-II in Breast Cancer Cells
Endocrinology 2005 146: 4224-4233, doi:10.1210/en.2004-1344 [Abstract] [Full Text] [PDF]  

V. C. Russo, B. S. Schütt, E. Andaloro, S. I. Ymer, A. Hoeflich, M. B. Ranke, L. A. Bach, and G. A. Werther

Insulin-Like Growth Factor Binding Protein-2 Binding to Extracellular Matrix Plays a Critical Role in Neuroblastoma Cell Proliferation, Migration, and Invasion
Endocrinology 2005 146: 4445-4455, doi:10.1210/en.2005-0467 [Abstract] [Full Text] [PDF]  

CRH-ACTH-POMC-ADRENAL:

Virginia H. Black, Archana Sanjay, Klaus van Leyen, Brett Lauring, and Gert Kreibich

Cholesterol and Steroid Synthesizing Smooth Endoplasmic Reticulum of Adrenocortical Cells Contains High Levels of Proteins Associated with the Translocation Channel
Endocrinology 2005 146: 4234-4249, doi:10.1210/en.2005-0372 [Abstract] [Full Text] [PDF]  

ENERGY BALANCE/OBESITY:

M. H. Vickers, P. D. Gluckman, A. H. Coveny, P. L. Hofman, W. S. Cutfield, A. Gertler, B. H. Breier, and M. Harris

Neonatal Leptin Treatment Reverses Developmental Programming
Endocrinology 2005 146: 4211-4216, doi:10.1210/en.2005-0581 [Abstract] [Full Text] [PDF]  

Sreenivasa Maddineni, Shana Metzger, Olga Ocón, Gilbert Hendricks, III, and Ramesh Ramachandran

Adiponectin Gene Is Expressed in Multiple Tissues in the Chicken: Food Deprivation Influences Adiponectin Messenger Ribonucleic Acid Expression
Endocrinology 2005 146: 4250-4256, doi:10.1210/en.2005-0254 [Abstract] [Full Text] [PDF]  

James L. Trevaskis and Andrew A. Butler

Double Leptin and Melanocortin-4 Receptor Gene Mutations Have an Additive Effect on Fat Mass and Are Associated with Reduced Effects of Leptin on Weight Loss and Food Intake
Endocrinology 2005 146: 4257-4265, doi:10.1210/en.2005-0492 [Abstract] [Full Text] [PDF]  

Marc Claret, Helena Corominola, Ignasi Canals, Josep Saura, Silvia Barcelo-Batllori, Joan J. Guinovart, and Ramon Gomis

Tungstate Decreases Weight Gain and Adiposity in Obese Rats through Increased Thermogenesis and Lipid Oxidation
Endocrinology 2005 146: 4362-4369, doi:10.1210/en.2005-0385 [Abstract] [Full Text] [PDF]  

Xiao Qiu Xiao, Kevin L. Grove, See Yan Lau, Shannon McWeeney, and M. Susan Smith

Deoxyribonucleic Acid Microarray Analysis of Gene Expression Pattern in the Arcuate Nucleus/Ventromedial Nucleus of Hypothalamus during Lactation
Endocrinology 2005 146: 4391-4398, doi:10.1210/en.2005-0561 [Abstract] [Full Text] [PDF]  

Gabor Voros, Erik Maquoi, Diego Demeulemeester, Natalie Clerx, Désiré Collen, and H. Roger Lijnen

Modulation of Angiogenesis during Adipose Tissue Development in Murine Models of Obesity
Endocrinology 2005 146: 4545-4554, doi:10.1210/en.2005-0532 [Abstract] [Full Text] [PDF]  

GENERAL ENDOCRINOLOGY:

Hong Chen, William Stuart, Bing Hu, Lisa Nguyen, Ganghua Huang, Thomas L. Clemens, and John S. Adams

Creation of Estrogen Resistance in Vivo by Transgenic Overexpression of the Heterogeneous Nuclear Ribonucleoprotein-Related Estrogen Response Element Binding Protein
Endocrinology 2005 146: 4266-4273, doi:10.1210/en.2005-0160 [Abstract] [Full Text] [PDF]  

M. Stefan, H. Ji, R. A. Simmons, D. E. Cummings, R. S. Ahima, M. I. Friedman, and R. D. Nicholls

Hormonal and Metabolic Defects in a Prader-Willi Syndrome Mouse Model with Neonatal Failure to Thrive
Endocrinology 2005 146: 4377-4385, doi:10.1210/en.2005-0371 [Abstract] [Full Text] [PDF]  

Loredana Quadro, Leora Hamberger, Max E. Gottesman, Fengwei Wang, Vittorio Colantuoni, William S. Blaner, and Cathy L. Mendelsohn

Pathways of Vitamin A Delivery to the Embryo: Insights from a New Tunable Model of Embryonic Vitamin A Deficiency
Endocrinology 2005 146: 4479-4490, doi:10.1210/en.2005-0158 [Abstract] [Full Text] [PDF]  

GROWTH FACTORS-CYTOKINES-ONCOGENES:

Laura Rico, Marcela Del Rio, Ana Bravo, Angel Ramirez, José L. Jorcano, M. Angustias Page, and Fernando Larcher

Targeted Overexpression of Leptin to Keratinocytes in Transgenic Mice Results in Lack of Skin Phenotype but Induction of Early Leptin Resistance
Endocrinology 2005 146: 4167-4176, doi:10.1210/en.2005-0156 [Abstract] [Full Text] [PDF]  

Lixia Gan, Haiyun Pan, and Terry G. Unterman

Insulin Response Sequence-Dependent and -Independent Mechanisms Mediate Effects of Insulin on Glucocorticoid-Stimulated Insulin-Like Growth Factor Binding Protein-1 Promoter Activity
Endocrinology 2005 146: 4274-4280, doi:10.1210/en.2005-0224 [Abstract] [Full Text] [PDF]  

INSULIN-GLUCAGON-GI PEPTIDES-DIABETES:

Lennart Friis-Hansen, Nils Wierup, Jens F. Rehfeld, and Frank Sundler

Reduced Ghrelin, Islet Amyloid Polypeptide, and Peptide YY Expression in the Stomach of Gastrin-Cholecystokinin Knockout Mice
Endocrinology 2005 146: 4464-4471, doi:10.1210/en.2004-0938 [Abstract] [Full Text] [PDF]  

Rebecca McGirr, Christina E. Ejbick, David E. Carter, Joseph D. Andrews, Ying Nie, Theodore C. Friedman, and Savita Dhanvantari

Glucose Dependence of the Regulated Secretory Pathway in TC1-6 Cells
Endocrinology 2005 146: 4514-4523, doi:10.1210/en.2005-0402 [Abstract] [Full Text] [PDF]  

INTRACELLULAR SIGNALING:

XingJia Wang, Chwan-Li Shen, Matthew T. Dyson, Sarah Eimerl, Joseph Orly, James C. Hutson, and Douglas M. Stocco

Cyclooxygenase-2 Regulation of the Age-Related Decline in Testosterone Biosynthesis
Endocrinology 2005 146: 4202-4208, doi:10.1210/en.2005-0298 [Abstract] [Full Text] [PDF]  

James B. Morris, Bronwyn Kenney, Huy Huynh, and Elizabeth A. Woodcock

Regulation of the Proapoptotic Factor FOXO1 (FKHR) in Cardiomyocytes by Growth Factors and ₁-Adrenergic Agonists
Endocrinology 2005 146: 4370-4376, doi:10.1210/en.2005-0162 [Abstract] [Full Text] [PDF]  

Aimee M. Dufresne and Robert J. Smith

The Adapter Protein GRB10 Is an Endogenous Negative Regulator of Insulin-Like Growth Factor Signaling
Endocrinology 2005 146: 4399-4409, doi:10.1210/en.2005-0150 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Moulun Luo, Sara Reyna, Lishan Wang, ZhengPing Yi, Christopher Carroll, Lily Q. Dong, Paul Langlais, Susan T. Weintraub, and Lawrence J. Mandarino

Identification of Insulin Receptor Substrate 1 Serine/Threonine Phosphorylation Sites Using Mass Spectrometry Analysis: Regulatory Role of Serine 1223
Endocrinology 2005 146: 4410-4416, doi:10.1210/en.2005-0260 [Abstract] [Full Text] [PDF]  

Ana I. Arroba, Laura M. Frago, Jesús Argente, and Julie A. Chowen

Activation of Caspase 8 in the Pituitaries of Streptozotocin-Induced Diabetic Rats: Implication in Increased Apoptosis of Lactotrophs
Endocrinology 2005 146: 4417-4424, doi:10.1210/en.2005-0517 [Abstract] [Full Text] [PDF]  

NEUROENDOCRINOLOGY:

D. K. Sarkar, K. Chaturvedi, S. Oomizu, N. I. Boyadjieva, and C. P. Chen

Dopamine, Dopamine D2 Receptor Short Isoform, Transforming Growth Factor (TGF)-ß1, and TGF-ß Type II Receptor Interact to Inhibit the Growth of Pituitary Lactotropes
Endocrinology 2005 146: 4179-4188, doi:10.1210/en.2005-0430 [Abstract] [Full Text] [PDF]  

Hirendra N. Sarma, Mohan Manikkam, Carol Herkimer, James Dell’Orco, Kathleen B. Welch, Douglas L. Foster, and Vasantha Padmanabhan

Fetal Programming: Excess Prenatal Testosterone Reduces Postnatal Luteinizing Hormone, But Not Follicle-Stimulating Hormone Responsiveness, to Estradiol Negative Feedback in the Female
Endocrinology 2005 146: 4281-4291, doi:10.1210/en.2005-0322 [Abstract] [Full Text] [PDF]  

Shi Di, Renato Malcher-Lopes, Victor L. Marcheselli, Nicolas G. Bazan, and Jeffrey G. Tasker

Rapid Glucocorticoid-Mediated Endocannabinoid Release and Opposing Regulation of Glutamate and -Aminobutyric Acid Inputs to Hypothalamic Magnocellular Neurons
Endocrinology 2005 146: 4292-4301, doi:10.1210/en.2005-0610 [Abstract] [Full Text] [PDF]  

D. Chesnoy-Marchais

The Estrogen Receptor Modulator Tamoxifen Enhances Spontaneous Glycinergic Synaptic Inhibition of Hypoglossal Motoneurons
Endocrinology 2005 146: 4302-4311, doi:10.1210/en.2005-0453 [Abstract] [Full Text] [PDF]  

Hideki Abe and Ei Terasawa

Firing Pattern and Rapid Modulation of Activity by Estrogen in Primate Luteinizing Hormone Releasing Hormone-1 Neurons
Endocrinology 2005 146: 4312-4320, doi:10.1210/en.2005-0435 [Abstract] [Full Text] [PDF]  

Roberto G. Romanelli, Tullio Barni, Mario Maggi, Michaela Luconi, Paola Failli, Anna Pezzatini, Annamaria Morelli, Roberto Maggi, Roberta Zaninetti, Roberto Salerno, Stefano Ambrosini, Mirca Marini, Carlo M. Rotella, and Gabriella B. Vannelli

Role of Endothelin-1 in the Migration of Human Olfactory Gonadotropin-Releasing Hormone-Secreting Neuroblasts
Endocrinology 2005 146: 4321-4330, doi:10.1210/en.2005-0060 [Abstract] [Full Text] [PDF]  

Johanna S. Schneider, Carly Burgess, Nicole C. Sleiter, Lydia L. DonCarlos, John P. Lydon, Bert O’Malley, and Jon E. Levine

Enhanced Sexual Behaviors and Androgen Receptor Immunoreactivity in the Male Progesterone Receptor Knockout Mouse
Endocrinology 2005 146: 4340-4348, doi:10.1210/en.2005-0490 [Abstract] [Full Text] [PDF]  

K. K. Soma, K. Sinchak, A. Lakhter, B. A. Schlinger, and P. E. Micevych

Neurosteroids and Female Reproduction: Estrogen Increases 3ß-HSD mRNA and Activity in Rat Hypothalamus
Endocrinology 2005 146: 4386-4390, doi:10.1210/en.2005-0569 [Abstract] [Full Text] [PDF]  

Mika Kinoshita, Hiroko Tsukamura, Sachika Adachi, Hisanori Matsui, Yoshihisa Uenoyama, Kinuyo Iwata, Shunji Yamada, Kinji Inoue, Tetsuya Ohtaki, Hirokazu Matsumoto, and Kei-Ichiro Maeda

Involvement of Central Metastin in the Regulation of Preovulatory Luteinizing Hormone Surge and Estrous Cyclicity in Female Rats
Endocrinology 2005 146: 4431-4436, doi:10.1210/en.2005-0195 [Abstract] [Full Text] [PDF]  

C. Michael Gammon, G. Mark Freeman, Jr., Wihua Xie, Sandra L. Petersen, and William C. Wetsel

Regulation of Gonadotropin-Releasing Hormone Secretion by Cannabinoids
Endocrinology 2005 146: 4491-4499, doi:10.1210/en.2004-1672 [Abstract] [Full Text] [PDF]  

PTH-CALCITONIN-VITAMIN D-BONE:

A. M. Schwab, S. Granholm, E. Persson, B. Wilkes, U. H. Lerner, and H. H. Conaway

Stimulation of Resorption in Cultured Mouse Calvarial Bones by Thiazolidinediones
Endocrinology 2005 146: 4349-4361, doi:10.1210/en.2005-0601 [Abstract] [Full Text] [PDF]  

REPRODUCTION-DEVELOPMENT:

Genevieve S. Neal-Perry, Gail D. Zeevalk, Nanette F. Santoro, and Anne M. Etgen

Attenuation of Preoptic Area Glutamate Release Correlates with Reduced Luteinizing Hormone Secretion in Middle-Aged Female Rats
Endocrinology 2005 146: 4331-4339, doi:10.1210/en.2005-0575 [Abstract] [Full Text] [PDF]  

Cheng-Guang Liang, Li-Jun Huo, Zhi-Sheng Zhong, Da-Yuan Chen, Heide Schatten, and Qing-Yuan Sun

Cyclic Adenosine 3',5'-Monophosphate-Dependent Activation of Mitogen-Activated Protein Kinase in Cumulus Cells Is Essential for Germinal Vesicle Breakdown of Porcine Cumulus-Enclosed Oocytes
Endocrinology 2005 146: 4437-4444, doi:10.1210/en.2005-0309 [Abstract] [Full Text] [PDF]  

R. Jasuja, D. H. Catlin, A. Miller, Y.-C. Chang, K. L. Herbst, B. Starcevic, J. N. Artaza, R. Singh, G. Datta, A. Sarkissian, C. Chandsawangbhuwana, M. Baker, and S. Bhasin

Tetrahydrogestrinone Is an Androgenic Steroid that Stimulates Androgen Receptor-Mediated, Myogenic Differentiation in C3H10T1/2 Multipotent Mesenchymal Cells and Promotes Muscle Accretion in Orchidectomized Male Rats
Endocrinology 2005 146: 4472-4478, doi:10.1210/en.2005-0448 [Abstract] [Full Text] [PDF]  

Lucie Tosca, Pascal Froment, Patricia Solnais, Pascal Ferré, Fabienne Foufelle, and Joëlle Dupont

Adenosine 5'-Monophosphate-Activated Protein Kinase Regulates Progesterone Secretion in Rat Granulosa Cells
Endocrinology 2005 146: 4500-4513, doi:10.1210/en.2005-0301 [Abstract] [Full Text] [PDF]  

Andrew G. Geiser, Conrad W. Hummel, Michael W. Draper, Judith W. Henck, Ilene R. Cohen, Daniel G. Rudmann, Kevin B Donnelly, Mary D. Adrian, Timothy A. Shepherd, Owen B. Wallace, Denis J. McCann, Samuel W. Oldham, Henry U. Bryant, Masahiko Sato, and Jeffrey A. Dodge

A New Selective Estrogen Receptor Modulator with Potent Uterine Antagonist Activity, Agonist Activity in Bone, and Minimal Ovarian Stimulation
Endocrinology 2005 146: 4524-4535, doi:10.1210/en.2005-0024 [Abstract] [Full Text] [PDF]  

Chris McKinnell, Richard M. Sharpe, Kim Mahood, Nina Hallmark, Hayley Scott, Richard Ivell, Christophe Staub, Bernard Jégou, Friedrich Haag, Friedrich Koch-Nolte, and Stefan Hartung

Expression of Insulin-Like Factor 3 Protein in the Rat Testis during Fetal and Postnatal Development and in Relation to Cryptorchidism Induced by in Utero Exposure to Di (n-Butyl) Phthalate
Endocrinology 2005 146: 4536-4544, doi:10.1210/en.2005-0676 [Abstract] [Full Text] [PDF]  

TRH-TSH-THYROID:

Joshua D. Safer, Tara M. Crawford, and Michael F. Holick

Topical Thyroid Hormone Accelerates Wound Healing in Mice
Endocrinology 2005 146: 4425-4430, doi:10.1210/en.2005-0192 [Abstract] [Full Text] [PDF]  

Caroline S. Kim, Vasily V. Vasko, Yasuhito Kato, Michael Kruhlak, Motoyasu Saji, Sheue-Yann Cheng, and Matthew D. Ringel

AKT Activation Promotes Metastasis in a Mouse Model of Follicular Thyroid Carcinoma
Endocrinology 2005 146: 4456-4463, doi:10.1210/en.2005-0172 [Abstract] [Full Text] [PDF]  

ANNOUNCEMENTS:

Société Française d’Endocrinologie, JOURNEES INTERNATIONALES D’ENDOCRINOLOGIE CLINIQUE
Endocrinology 2005 146: 4430 [Full Text] [PDF]  

Call for Papers: Systems/Integrative Endocrinology
Endocrinology 2005 146: 4523 [Full Text] [PDF]  

RESEARCH RESOURCES:

Endocrine-Related Resources from the National Institutes of Health
Endocrinology 2005 146: 4555-4558 [Full Text] [PDF]  

National Hormone & Peptide Program (NHPP): New Recombinant Hormones, Hypothalamic Peptides, Natural Hormones, New Antisera, & Expanded Hormone Assay Services Available
Endocrinology 2005 146: 4559-4561 [Full Text] [PDF]  

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