NEWS & VIEWS:

Mario Ascoli

Learning New Tricks from an Old Dog: The Processing of the Intracellular Precursor of the Luteinizing Hormone Receptor (LHR) into the Mature Cell-Surface LHR Is a Regulated Process
Endocrinology 2005 146: 3221-3223, doi:10.1210/en.2005-0590 [Full Text] [PDF]  

Sundeep Khosla

Magic Bullets to Kill Nasty Osteoclasts
Endocrinology 2005 146: 3233-3234, doi:10.1210/en.2005-0549 [Full Text] [PDF]  

Teresa K. Woodruff and Kelly E. Mayo

To ß or Not To ß: Estrogen Receptors and Ovarian Function
Endocrinology 2005 146: 3244-3246, doi:10.1210/en.2005-0630 [Full Text] [PDF]  

Yasuo Terauchi and Takashi Kadowaki

Peroxisome Proliferator-Activated Receptors and Insulin Secretion
Endocrinology 2005 146: 3263-3265, doi:10.1210/en.2005-0526 [Full Text] [PDF]  

Geert J. De Vries

Sex Steroids and Sex Chromosomes at Odds?
Endocrinology 2005 146: 3277-3279, doi:10.1210/en.2005-0612 [Full Text] [PDF]  

BRIEF COMMUNICATIONS:

Karen M. Palaszynski, Deborah L. Smith, Shana Kamrava, Paul S. Burgoyne, Arthur P. Arnold, and Rhonda R. Voskuhl

A Yin-Yang Effect between Sex Chromosome Complement and Sex Hormones on the Immune Response
Endocrinology 2005 146: 3280-3285, doi:10.1210/en.2005-0284 [Abstract] [Full Text] [PDF]  

CANCER:

Sean Morony, Kelly Warmington, Stephen Adamu, Frank Asuncion, Zhaopo Geng, Mario Grisanti, Hong Lin Tan, Casey Capparelli, Charlie Starnes, Bernadette Weimann, Colin R. Dunstan, and Paul J. Kostenuik

The Inhibition of RANKL Causes Greater Suppression of Bone Resorption and Hypercalcemia Compared with Bisphosphonates in Two Models of Humoral Hypercalcemia of Malignancy
Endocrinology 2005 146: 3235-3243, doi:10.1210/en.2004-1583 [Abstract] [Full Text] [PDF]  

John J. Grzesiak, Kathy C. Smith, Cheryl Chalberg, Caitlyn Truong, Douglas W. Burton, Leonard J. Deftos, and Michael Bouvet

Heat Shock Protein-70 Expressed on the Surface of Cancer Cells Binds Parathyroid Hormone-Related Protein in Vitro
Endocrinology 2005 146: 3567-3576, doi:10.1210/en.2005-0351 [Abstract] [Full Text] [PDF]  

Yayun Liang and Salman M. Hyder

Proliferation of Endothelial and Tumor Epithelial Cells by Progestin-Induced Vascular Endothelial Growth Factor from Human Breast Cancer Cells: Paracrine and Autocrine Effects
Endocrinology 2005 146: 3632-3641, doi:10.1210/en.2005-0103 [Abstract] [Full Text] [PDF]  

CRH-ACTH-POMC-ADRENAL:

Juan R. Peinado, Virginie Laurent, Sang-Nam Lee, Bonnie W. Peng, John E. Pintar, Donald F. Steiner, and Iris Lindberg

Strain-Dependent Influences on the Hypothalamo-Pituitary-Adrenal Axis Profoundly Affect the 7B2 and PC2 Null Phenotypes
Endocrinology 2005 146: 3438-3444, doi:10.1210/en.2004-1289 [Abstract] [Full Text] [PDF]  

Jeremiah Seely, Karla Saner Amigh, Takashi Suzuki, Bobbie Mayhew, Hironobu Sasano, Vincent Giguere, Josée Laganière, Bruce R. Carr, and William E. Rainey

Transcriptional Regulation of Dehydroepiandrosterone Sulfotransferase (SULT2A1) by Estrogen-Related Receptor
Endocrinology 2005 146: 3605-3613, doi:10.1210/en.2004-1619 [Abstract] [Full Text] [PDF]  

ENERGY BALANCE/OBESITY:

B. M. C. McGowan, S. A. Stanley, K. L. Smith, N. E. White, M. M. Connolly, E. L. Thompson, J. V. Gardiner, K. G. Murphy, M. A. Ghatei, and S. R. Bloom

Central Relaxin-3 Administration Causes Hyperphagia in Male Wistar Rats
Endocrinology 2005 146: 3295-3300, doi:10.1210/en.2004-1532 [Abstract] [Full Text] [PDF]  

Qihong Zhu, Grant W. Anderson, Gregory T. Mucha, Elizabeth J. Parks, Jennifer K. Metkowski, and Cary N. Mariash

The Spot 14 Protein Is Required for de Novo Lipid Synthesis in the Lactating Mammary Gland
Endocrinology 2005 146: 3343-3350, doi:10.1210/en.2005-0204 [Abstract] [Full Text] [PDF]  

Ryuji Kouyama, Takayoshi Suganami, Junko Nishida, Miyako Tanaka, Takuya Toyoda, Minako Kiso, Tsuyoshi Chiwata, Yoshihiro Miyamoto, Yasunao Yoshimasa, Akiyoshi Fukamizu, Masatsugu Horiuchi, Yukio Hirata, and Yoshihiro Ogawa

Attenuation of Diet-Induced Weight Gain and Adiposity through Increased Energy Expenditure in Mice Lacking Angiotensin II Type 1a Receptor
Endocrinology 2005 146: 3481-3489, doi:10.1210/en.2005-0003 [Abstract] [Full Text] [PDF]  

Yukari Date, Koji Toshinai, Shuichi Koda, Mikiya Miyazato, Takuya Shimbara, Tomoko Tsuruta, Akira Niijima, Kenji Kangawa, and Masamitsu Nakazato

Peripheral Interaction of Ghrelin with Cholecystokinin on Feeding Regulation
Endocrinology 2005 146: 3518-3525, doi:10.1210/en.2004-1240 [Abstract] [Full Text] [PDF]  

Gavin A. Bewick, Waljit S. Dhillo, Sarah J. Darch, Kevin G. Murphy, James V. Gardiner, Preeti H. Jethwa, Wing May Kong, Mohammed A. Ghatei, and Stephen R. Bloom

Hypothalamic Cocaine- and Amphetamine-Regulated Transcript (CART) and Agouti-Related Protein (AgRP) Neurons Coexpress the NOP₁ Receptor and Nociceptin Alters CART and AgRP Release
Endocrinology 2005 146: 3526-3534, doi:10.1210/en.2004-1659 [Abstract] [Full Text] [PDF]  

GENERAL ENDOCRINOLOGY:

Emanuela Esposito, Anna Iacono, Giuseppina Mattace Raso, Maria Pacilio, Anna Coppola, Raffaele Di Carlo, and Rosaria Meli

Raloxifene, a Selective Estrogen Receptor Modulator, Reduces Carrageenan-Induced Acute Inflammation in Normal and Ovariectomized Rats
Endocrinology 2005 146: 3301-3308, doi:10.1210/en.2005-0375 [Abstract] [Full Text] [PDF]  

Kathryn M. Gauthier, David X. Zhang, Erik M. Edwards, Blythe Holmes, and William B. Campbell

Angiotensin II Dilates Bovine Adrenal Cortical Arterioles: Role of Endothelial Nitric Oxide
Endocrinology 2005 146: 3319-3324, doi:10.1210/en.2005-0129 [Abstract] [Full Text] [PDF]  

Martha Lappas, Michael Permezel, and Gregory E. Rice

Leptin and Adiponectin Stimulate the Release of Proinflammatory Cytokines and Prostaglandins from Human Placenta and Maternal Adipose Tissue via Nuclear Factor-B, Peroxisomal Proliferator-Activated Receptor- and Extracellularly Regulated Kinase 1/2
Endocrinology 2005 146: 3334-3342, doi:10.1210/en.2005-0406 [Abstract] [Full Text] [PDF]  

Tamar D. Schirman-Hildesheim, Tzachi Bar, Nurit Ben-Aroya, and Yitzhak Koch

Differential Gonadotropin-Releasing Hormone (GnRH) and GnRH Receptor Messenger Ribonucleic Acid Expression Patterns in Different Tissues of the Female Rat across the Estrous Cycle
Endocrinology 2005 146: 3401-3408, doi:10.1210/en.2005-0240 [Abstract] [Full Text] [PDF]  

Anna Johansson, Stina Häggström Rudolfsson, Pernilla Wikström, and Anders Bergh

Altered Levels of Angiopoietin 1 and Tie 2 Are Associated with Androgen-Regulated Vascular Regression and Growth in the Ventral Prostate in Adult Mice and Rats
Endocrinology 2005 146: 3463-3470, doi:10.1210/en.2004-1480 [Abstract] [Full Text] [PDF]  

Sandra Filippi, Annamaria Morelli, Linda Vignozzi, Gabriella Barbara Vannelli, Mirca Marini, Pietro Ferruzzi, Rosa Mancina, Clara Crescioli, Nicola Mondaini, Gianni Forti, Fabrizio Ledda, and Mario Maggi

Oxytocin Mediates the Estrogen-Dependent Contractile Activity of Endothelin-1 in Human and Rabbit Epididymis
Endocrinology 2005 146: 3506-3517, doi:10.1210/en.2004-1628 [Abstract] [Full Text] [PDF]  

Jorge N. Artaza, Shalender Bhasin, Thomas R. Magee, Suzanne Reisz-Porszasz, Ruoquin Shen, Nigel P. Groome, Meerasaluh M. Fareez, and Nestor F. Gonzalez-Cadavid

Myostatin Inhibits Myogenesis and Promotes Adipogenesis in C3H 10T(1/2) Mesenchymal Multipotent Cells
Endocrinology 2005 146: 3547-3557, doi:10.1210/en.2005-0362 [Abstract] [Full Text] [PDF]  

INSULIN-GLUCAGON-GI PEPTIDES-DIABETES:

Kim Ravnskjaer, Michael Boergesen, Blanca Rubi, Jan K. Larsen, Tina Nielsen, Jakob Fridriksson, Pierre Maechler, and Susanne Mandrup

Peroxisome Proliferator-Activated Receptor (PPAR) Potentiates, whereas PPAR Attenuates, Glucose-Stimulated Insulin Secretion in Pancreatic ß-Cells
Endocrinology 2005 146: 3266-3276, doi:10.1210/en.2004-1430 [Abstract] [Full Text] [PDF]  

Tadao Iwasaki, Sadao Takahashi, Masao Takahashi, Yasuo Zenimaru, Takeshi Kujiraoka, Mitsuaki Ishihara, Makoto Nagano, Jinya Suzuki, Isamu Miyamori, Hironobu Naiki, Juro Sakai, Takahiro Fujino, Norman E. Miller, Tokuo T. Yamamoto, and Hiroaki Hattori

Deficiency of the Very Low-Density Lipoprotein (VLDL) Receptors in Streptozotocin-Induced Diabetic Rats: Insulin Dependency of the VLDL Receptor
Endocrinology 2005 146: 3286-3294, doi:10.1210/en.2005-0043 [Abstract] [Full Text] [PDF]  

M. L. Gavete, M. A. Martín, C. Alvarez, and F. Escrivá

Maternal Food Restriction Enhances Insulin-Induced GLUT-4 Translocation and Insulin Signaling Pathway in Skeletal Muscle from Suckling Rats
Endocrinology 2005 146: 3368-3378, doi:10.1210/en.2004-1658 [Abstract] [Full Text] [PDF]  

Peter J. Klover, Alicia H. Clementi, and Robert A. Mooney

Interleukin-6 Depletion Selectively Improves Hepatic Insulin Action in Obesity
Endocrinology 2005 146: 3417-3427, doi:10.1210/en.2004-1468 [Abstract] [Full Text] [PDF]  

Sergiu Botolin, Marie-Claude Faugere, Hartmut Malluche, Michael Orth, Ron Meyer, and Laura R. McCabe

Increased Bone Adiposity and Peroxisomal Proliferator-Activated Receptor-2 Expression in Type I Diabetic Mice
Endocrinology 2005 146: 3622-3631, doi:10.1210/en.2004-1677 [Abstract] [Full Text] [PDF]  

INTRACELLULAR SIGNALING:

Anthony I. Vulin, Kirsten K. Jacob, and Frederick M. Stanley

Integrin Activates Receptor-Like Protein Tyrosine Phosphatase , Src, and Rho to Increase Prolactin Gene Expression through a Final Phosphatidylinositol 3-Kinase/Cytoskeletal Pathway that Is Additive with Insulin
Endocrinology 2005 146: 3535-3546, doi:10.1210/en.2004-1386 [Abstract] [Full Text] [PDF]  

NEUROENDOCRINOLOGY:

I. Charalampopoulos, E. Dermitzaki, L. Vardouli, C. Tsatsanis, C. Stournaras, A. N. Margioris, and A. Gravanis

Dehydroepiandrosterone Sulfate and Allopregnanolone Directly Stimulate Catecholamine Production via Induction of Tyrosine Hydroxylase and Secretion by Affecting Actin Polymerization
Endocrinology 2005 146: 3309-3318, doi:10.1210/en.2005-0263 [Abstract] [Full Text] [PDF]  

Kazutaka Mogi, Toshiya Funabashi, Dai Mitsushima, Hiroko Hagiwara, and Fukuko Kimura

Sex Difference in the Response of Melanin-Concentrating Hormone Neurons in the Lateral Hypothalamic Area to Glucose, as Revealed by the Expression of Phosphorylated Cyclic Adenosine 3',5'-Monophosphate Response Element-Binding Protein
Endocrinology 2005 146: 3325-3333, doi:10.1210/en.2005-0078 [Abstract] [Full Text] [PDF]  

Matthew R. Silver, Nathaniel V. Nucci, Adam R. Root, Karen L. Reed, and Stacia A. Sower

Cloning and Characterization of a Functional Type II Gonadotropin-Releasing Hormone Receptor with a Lengthy Carboxy-Terminal Tail from an Ancestral Vertebrate, the Sea Lamprey
Endocrinology 2005 146: 3351-3361, doi:10.1210/en.2005-0305 [Abstract] [Full Text] [PDF]  

Takahiko Fujikawa, Kenji Tamura, Tomoko Kawase, Yoshiko Mori, Randall R. Sakai, Kunihiro Sakuma, Akihiko Yamaguch, Masato Ogata, Hideaki Soya, and Kunio Nakashima

Prolactin Receptor Knockdown in the Rat Paraventricular Nucleus by a Morpholino-Antisense Oligonucleotide Causes Hypocalcemia and Stress Gastric Erosion
Endocrinology 2005 146: 3471-3480, doi:10.1210/en.2004-1528 [Abstract] [Full Text] [PDF]  

PTH-CALCITONIN-VITAMIN D-BONE:

Alexander P. Alimov, Ok-Kyong Park-Sarge, Kevin D. Sarge, Hartmut H. Malluche, and Nicholas J. Koszewski

Transactivation of the Parathyroid Hormone Promoter by Specificity Proteins and the Nuclear Factor Y Complex
Endocrinology 2005 146: 3409-3416, doi:10.1210/en.2005-0272 [Abstract] [Full Text] [PDF]  

Anna M. Osyczka and Phoebe S. Leboy

Bone Morphogenetic Protein Regulation of Early Osteoblast Genes in Human Marrow Stromal Cells Is Mediated by Extracellular Signal-Regulated Kinase and Phosphatidylinositol 3-Kinase Signaling
Endocrinology 2005 146: 3428-3437, doi:10.1210/en.2005-0303 [Abstract] [Full Text] [PDF]  

Svetlana V. Komarova

Mathematical Model of Paracrine Interactions between Osteoclasts and Osteoblasts Predicts Anabolic Action of Parathyroid Hormone on Bone
Endocrinology 2005 146: 3589-3595, doi:10.1210/en.2004-1642 [Abstract] [Full Text] [PDF]  

Aline Martin, Raphaël de Vittoris, Valentin David, Ricardo Moraes, Martine Bégeot, Marie-Hélène Lafage-Proust, Christian Alexandre, Laurence Vico, and Thierry Thomas

Leptin Modulates both Resorption and Formation while Preventing Disuse-Induced Bone Loss in Tail-Suspended Female Rats
Endocrinology 2005 146: 3652-3659, doi:10.1210/en.2004-1509 [Abstract] [Full Text] [PDF]  

RECEPTORS:

John F. Couse, Mariana M. Yates, Bonnie J. Deroo, and Kenneth S. Korach

Estrogen Receptor-ß Is Critical to Granulosa Cell Differentiation and the Ovulatory Response to Gonadotropins
Endocrinology 2005 146: 3247-3262, doi:10.1210/en.2005-0213 [Abstract] [Full Text] [PDF]  

Wen Ting Wu, Chiung-Nien Chen, Chi Iou Lin, Jiun Hong Chen, and Hsinyu Lee

Lysophospholipids Enhance Matrix Metalloproteinase-2 Expression in Human Endothelial Cells
Endocrinology 2005 146: 3387-3400, doi:10.1210/en.2004-1654 [Abstract] [Full Text] [PDF]  

Yumiko Saito, Mitsue Tetsuka, Seiji Saito, Kensaku Imai, Ayumu Yoshikawa, Hirofumi Doi, and Kei Maruyama

Arginine Residue 155 in the Second Intracellular Loop Plays a Critical Role in Rat Melanin-Concentrating Hormone Receptor 1 Activation
Endocrinology 2005 146: 3452-3462, doi:10.1210/en.2005-0115 [Abstract] [Full Text] [PDF]  

Jae-Wook Jeong, Kevin Y. Lee, Inseok Kwak, Lisa D. White, Susan G. Hilsenbeck, John P. Lydon, and Francesco J. DeMayo

Identification of Murine Uterine Genes Regulated in a Ligand-Dependent Manner by the Progesterone Receptor
Endocrinology 2005 146: 3490-3505, doi:10.1210/en.2005-0016 [Abstract] [Full Text] [PDF] [Supplemental Tables]  

Mark D. Aupperlee, Kyle T. Smith, Anastasia Kariagina, and Sandra Z. Haslam

Progesterone Receptor Isoforms A and B: Temporal and Spatial Differences in Expression during Murine Mammary Gland Development
Endocrinology 2005 146: 3577-3588, doi:10.1210/en.2005-0346 [Abstract] [Full Text] [PDF]  

Satoko Sudo, Yoshimitsu Kuwabara, Jae-Il Park, Sheau Yu Hsu, and Aaron J. W. Hsueh

Heterodimeric Fly Glycoprotein Hormone-2 (GPA2) and Glycoprotein Hormone-ß5 (GPB5) Activate Fly Leucine-Rich Repeat-Containing G Protein-Coupled Receptor-1 (DLGR1) and Stimulation of Human Thyrotropin Receptors by Chimeric Fly GPA2 and Human GPB5
Endocrinology 2005 146: 3596-3604, doi:10.1210/en.2005-0317 [Abstract] [Full Text] [PDF]  

REPRODUCTION-DEVELOPMENT:

Pirjo M. Apaja, Jyrki T. Aatsinki, Hannu J. Rajaniemi, and Ulla E. Petäjä-Repo

Expression of the Mature Luteinizing Hormone Receptor in Rodent Urogenital and Adrenal Tissues Is Developmentally Regulated at a Posttranslational Level
Endocrinology 2005 146: 3224-3232, doi:10.1210/en.2005-0073 [Abstract] [Full Text] [PDF]  

Fumio Otsuka, R. Kelly Moore, Xia Wang, Shweta Sharma, Tomoko Miyoshi, and Shunichi Shimasaki

Essential Role of the Oocyte in Estrogen Amplification of Follicle-Stimulating Hormone Signaling in Granulosa Cells
Endocrinology 2005 146: 3362-3367, doi:10.1210/en.2005-0349 [Abstract] [Full Text] [PDF]  

Yuki Omori, Kazuto Nakamura, Soichi Yamashita, Hiroko Matsuda, Tetsuya Mizutani, Kaoru Miyamoto, and Takashi Minegishi

Effect of Follicle-Stimulating Hormone and Estrogen on the Expression of Betaglycan Messenger Ribonucleic Acid Levels in Cultured Rat Granulosa Cells
Endocrinology 2005 146: 3379-3386, doi:10.1210/en.2004-1665 [Abstract] [Full Text] [PDF]  

Xiaolan Fei, Hajin Chung, and Hugh S. Taylor

Methoxychlor Disrupts Uterine Hoxa10 Gene Expression
Endocrinology 2005 146: 3445-3451, doi:10.1210/en.2005-0341 [Abstract] [Full Text] [PDF]  

Mark Wijgerde, Marja Ooms, Jos W. Hoogerbrugge, and J. Anton Grootegoed

Hedgehog Signaling in Mouse Ovary: Indian Hedgehog and Desert Hedgehog from Granulosa Cells Induce Target Gene Expression in Developing Theca Cells
Endocrinology 2005 146: 3558-3566, doi:10.1210/en.2005-0311 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Yin Xia, Yisrael Sidis, Abir Mukherjee, Tarek A. Samad, Gary Brenner, Clifford J. Woolf, Herbert Y. Lin, and Alan Schneyer

Localization and Action of Dragon (Repulsive Guidance Molecule b), a Novel Bone Morphogenetic Protein Coreceptor, throughout the Reproductive Axis
Endocrinology 2005 146: 3614-3621, doi:10.1210/en.2004-1676 [Abstract] [Full Text] [PDF]  

TRH-TSH-THYROID:

Hiroaki Kimura, Shey-Cherng Tzou, Roberto Rocchi, Miho Kimura, Koichi Suzuki, Albert F. Parlow, Noel R. Rose, and Patrizio Caturegli

Interleukin (IL)-12-Driven Primary Hypothyroidism: the Contrasting Roles of Two Th1 Cytokines (IL-12 and Interferon-)
Endocrinology 2005 146: 3642-3651, doi:10.1210/en.2005-0275 [Abstract] [Full Text] [PDF]  

ANNOUNCEMENTS:

International Osteoporosis Foundation-Servier RESEARCH AWARD IN OSTEOPOROSIS
Endocrinology 2005 146: 3517 [Full Text] [PDF]  

RESEARCH RESOURCES:

Endocrine-Related Resources from the National Institutes of Health
Endocrinology 2005 146: 3673-3676 [Full Text] [PDF]  

National Hormone & Peptide Program (NHPP): New Recombinant Hormones, Hypothalamic Peptides, Natural Hormones, New Antisera, & Expanded Hormone Assay Services Available
Endocrinology 2005 146: 3677-3679 [Full Text] [PDF]  

THE ENDOCRINE SOCIETY:

The Endocrine Society Laureate Awards
Endocrinology 2005 146: 3660-3661 [Full Text] [PDF]  

THE ENDOCRINE SOCIETY 2005 LAUREATE AWARDS
Endocrinology 2005 146: 3662-3672 [Full Text] [PDF]  

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