NEWS AND VIEWS:

Kim Wallen

Does Finger Fat Produce Sex Differences in Second to Fourth Digit Ratios?
Endocrinology 2009 150: 4819-4822 doi:10.1210/en.2009-0986 [Full Text] [PDF]  

CALCIUM-REGULATING HORMONES:

Norikazu Ota, Hironari Takaishi, Naoto Kosaki, Jiro Takito, Masaki Yoda, Takahide Tohmonda, Tokuhiro Kimura, Yasunori Okada, Hisataka Yasuda, Hiroshi Kawaguchi, Morio Matsumoto, Kazuhiro Chiba, Hiroyasu Ikegami, and Yoshiaki Toyama

Accelerated Cartilage Resorption by Chondroclasts during Bone Fracture Healing in Osteoprotegerin-Deficient Mice
Endocrinology 2009 150: 4823-4834 , doi:10.1210/en.2009-0452 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Osteoprotegerin produced by chondrocytes negatively regulates the chondrocyte-dependent formation of tartrate-resistant acid phosphatase-positive multinucleated cells (chondroclasts) that resorb cartilage matrix.

Rana Samadfam, Christian Richard, Loan Nguyen-Yamamoto, Isabel Bolivar, and David Goltzman

Bone Formation Regulates Circulating Concentrations of Fibroblast Growth Factor 23
Endocrinology 2009 150: 4835-4845 , doi:10.1210/en.2009-0472 [Abstract] [Full Text] [PDF]  
Analyses of mouse models of altered bone turnover provide evidence that bone formation regulates circulating concentrations of FGF23.

CANCER-ONCOGENES:

John J. Peluso, Anna Gawkowska, Xiufang Liu, Toshi Shioda, and James K. Pru

Progesterone Receptor Membrane Component-1 Regulates the Development and Cisplatin Sensitivity of Human Ovarian Tumors in Athymic Nude Mice
Endocrinology 2009 150: 4846-4854 , doi:10.1210/en.2009-0730 [Abstract] [Full Text] [PDF]  
Progesterone receptor membrane component 1 plays an essential role in the development and cisplatin sensitivity of human ovarian tumors grown in athymic nude mice.

DIABETES-INSULIN-GLUCAGON-GASTROINTESTINAL:

Jamie S. Harmon, Marika Bogdani, Susan D. Parazzoli, Sabrina S. M. Mak, Elizabeth A. Oseid, Marleen Berghmans, Renée C. LeBoeuf, and R. Paul Robertson

β-Cell-Specific Overexpression of Glutathione Peroxidase Preserves Intranuclear MafA and Reverses Diabetes in db/db Mice
Endocrinology 2009 150: 4855-4862 , doi:10.1210/en.2009-0708 [Abstract] [Full Text] [PDF] [Supplemental Data]  
β-cell-specific GPx-1 overexpression in db/db mice protects the β-cell from oxidative stress and progression in dysfunction associated with chronic hyperglycemia.

Vijay Yechoor, Victoria Liu, Antoni Paul, Jeongkyung Lee, Eric Buras, Kerem Ozer, Susan Samson, and Lawrence Chan

Gene Therapy with Neurogenin 3 and Betacellulin Reverses Major Metabolic Problems in Insulin-Deficient Diabetic Mice
Endocrinology 2009 150: 4863-4873 , doi:10.1210/en.2009-0527 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Neurogenin 3 plus betacellulin gene therapy induces neo-islets in the liver with gene expression profile and ultrastructure closely simulating normal β-cells, reversing major metabolic derangements of diabetes in mice.

Jennifer W. Hill, Yong Xu, Frederic Preitner, Makota Fukuda, You-Ree Cho, Ji Luo, Nina Balthasar, Roberto Coppari, Lewis C. Cantley, Barbara B. Kahn, Jean J. Zhao, and Joel K. Elmquist

Phosphatidyl Inositol 3-Kinase Signaling in Hypothalamic Proopiomelanocortin Neurons Contributes to the Regulation of Glucose Homeostasis
Endocrinology 2009 150: 4874-4882 , doi:10.1210/en.2009-0454 [Abstract] [Full Text] [PDF] [Supplemental Data]  
The activity of the PI3K pathway in proopiomelanocortin (POMC) neurons is involved not only in normal energy regulation but also glucose homeostasis.

Sarah J. Lessard, Donato A. Rivas, Zhi-Ping Chen, Bryce J. van Denderen, Matthew J. Watt, Lauren G. Koch, Steven L. Britton, Bruce E. Kemp, and John A. Hawley

Impaired Skeletal Muscle β-Adrenergic Activation and Lipolysis Are Associated with Whole-Body Insulin Resistance in Rats Bred for Low Intrinsic Exercise Capacity
Endocrinology 2009 150: 4883-4891 , doi:10.1210/en.2009-0158 [Abstract] [Full Text] [PDF]  
Reduced β-adrenergic signaling in muscle is associated with impaired metabolic health.

ENERGY BALANCE-OBESITY:

Chih-Chan Lien, Lo-Chun Au, Ying-Lan Tsai, Low-Tone Ho, and Chi-Chang Juan

Short-Term Regulation of Tumor Necrosis Factor--Induced Lipolysis in 3T3-L1 Adipocytes Is Mediated through the Inducible Nitric Oxide Synthase/Nitric Oxide-Dependent Pathway
Endocrinology 2009 150: 4892-4900 , doi:10.1210/en.2009-0403 [Abstract] [Full Text] [PDF]  
Short-term TNF- treatment induces lipolysis in 3T3-L1 adipocytes by increasing inducible nitric oxide (NO) synthesis expression and NO production, which activates the guanylyl cyclase/cGMP-dependent pathway.

Joanna Pohl, Barbara Woodside, and Giamal N. Luheshi

Changes in Hypothalamically Mediated Acute-Phase Inflammatory Responses to Lipopolysaccharide in Diet-Induced Obese Rats
Endocrinology 2009 150: 4901-4910 , doi:10.1210/en.2009-0526 [Abstract] [Full Text] [PDF]  
Obese rats show increased fever, higher circulating cytokines, and an increased capacity of white adipose tissue to secrete pro-inflammatory cytokines following an acute immune challenge.

Andreas Stengel, Miriam Goebel, Lixin Wang, Jean Rivier, Peter Kobelt, Hubert Mönnikes, Nils W. G. Lambrecht, and Yvette Taché

Central Nesfatin-1 Reduces Dark-Phase Food Intake and Gastric Emptying in Rats: Differential Role of Corticotropin-Releasing Factor₂ Receptor
Endocrinology 2009 150: 4911-4919 , doi:10.1210/en.2009-0578 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Nesfatin-1’s anorectic effect on dark phase food intake is CRF₂-receptor dependent after injection into the forebrain ventricular site but CRF₂-independent after injection into hindbrain sites, and is independent from a decrease in gastric emptying.

Pia Steen Petersen, David P. D. Woldbye, Andreas Nygaard Madsen, Kristoffer L. Egerod, Chunyu Jin, Manja Lang, Maria Rasmussen, Annette G. Beck-Sickinger, and Birgitte Holst

In Vivo Characterization of High Basal Signaling from the Ghrelin Receptor
Endocrinology 2009 150: 4920-4930 , doi:10.1210/en.2008-1638 [Abstract] [Full Text] [PDF]  
The importance of high constitutive signaling of the ghrelin receptor for gene regulation, food intake, and body weight is demonstrated by in vivo studies in rats.

Michael K. Badman, Anja Koester, Jeffrey S. Flier, Alexei Kharitonenkov, and Eleftheria Maratos-Flier

Fibroblast Growth Factor 21-Deficient Mice Demonstrate Impaired Adaptation to Ketosis
Endocrinology 2009 150: 4931-4940 , doi:10.1210/en.2009-0532 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Mice globally deficient in FGF21 have a mild obesity phenotype when fed chow, are able to withstand acute fasting, but develop obesity when fed a high fat low carbohydrate ketogenic diet.

GENERAL ENDOCRINOLOGY:

ZhongYi Shen, Taija Saloniemi, Aino Rönnblad, Päivi Järvensivu, Pirjo Pakarinen, and Matti Poutanen

Sex Steroid-Dependent and -Independent Action of Hydroxysteroid (17β) Dehydrogenase 2: Evidence from Transgenic Female Mice
Endocrinology 2009 150: 4941-4949 , doi:10.1210/en.2009-0670 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Human hydroxysteroid (17β) dehydrogenase 2 modulates action of estrogens, but has also a role in sex steroid-independent growth retardation in transgenic mice.

Peter J. Malloy, Jining Wang, Kristin Jensen, and David Feldman

Modulation of Vitamin D Receptor Activity by the Corepressor Hairless: Differential Effects of Hairless Isoforms
Endocrinology 2009 150: 4950-4957 , doi:10.1210/en.2009-0358 [Abstract] [Full Text] [PDF]  
Hairless (HR) is a VDR corepressor expressed as two isoforms, but the alternatively spliced short isoform is unable to bind histone deacetylases and lacks corepressor activity.

GLUCOCORTICOIDS-CRH-ACTH-ADRENAL:

Caroline Rivers, Andrea Flynn, Xiaoxiao Qian, Laura Matthews, Stafford Lightman, David Ray, and Michael Norman

Characterization of Conserved Tandem Donor Sites and Intronic Motifs Required for Alternative Splicing in Corticosteroid Receptor Genes
Endocrinology 2009 150: 4958-4967 , doi:10.1210/en.2009-0346 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Alternative splicing from tandem donor sites in mRNA variants encoding additional amino acids in the DNA binding domains of corticosteroid receptor genes is shown to be highly conserved in mammalian species.

GROWTH FACTORS-CYTOKINES:

Xiaolang Yan, Louis D. Payet, Robert C. Baxter, and Sue M. Firth

Activity of Human Pregnancy Insulin-Like Growth Factor Binding Protein-3: Determination by Reconstituting Recombinant Complexes
Endocrinology 2009 150: 4968-4976 , doi:10.1210/en.2009-0090 [Abstract] [Full Text] [PDF]  
During pregnancy, circulating IGFBP-3 is proteolyzed into two complementary fragments that cooperate to maintain its IGF binding and transport functions.

Y. Wittrant, Y. Gorin, S. Mohan, B. Wagner, and S. L. Abboud-Werner

Colony-Stimulating Factor-1 (CSF-1) Directly Inhibits Receptor Activator of Nuclear Factor-B Ligand (RANKL) Expression by Osteoblasts
Endocrinology 2009 150: 4977-4988 , doi:10.1210/en.2009-0248 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Osteoblasts express CSF-1 receptor, and CSF-1-mediated inhibition of RANKL in osteoblasts is associated with decreased Nox oxidases.

Chandi C. Mandal, Goutam Ghosh Choudhury, and Nandini Ghosh-Choudhury

Phosphatidylinositol 3 Kinase/Akt Signal Relay Cooperates with Smad in Bone Morphogenetic Protein-2-Induced Colony Stimulating Factor-1 (CSF-1) Expression and Osteoclast Differentiation
Endocrinology 2009 150: 4989-4998 , doi:10.1210/en.2009-0026 [Abstract] [Full Text] [PDF] [Supplemental Data]  
PI3K signaling regulates BMP-2-induced osteoblastic cell-assisted osteoclast formation by regulating expression of CSF-1.

GROWTH HORMONE-SOMATOSTATIN-GRH:

Gregory A. Dunn and Tracy L. Bale

Maternal High-Fat Diet Promotes Body Length Increases and Insulin Insensitivity in Second-Generation Mice
Endocrinology 2009 150: 4999-5009 , doi:10.1210/en.2009-0500 [Abstract] [Full Text] [PDF] [Supplemental Data]  
The heritability of body length and glucose homeostasis are modulated by maternal diet across multiple generations, providing a mechanism by which length can increase rapidly in concert with caloric availability.

NEUROENDOCRINOLOGY:

George Barreto, María Santos-Galindo, Yolanda Diz-Chaves, Olga Pernía, Paloma Carrero, Iñigo Azcoitia, and Luis M. Garcia-Segura

Selective Estrogen Receptor Modulators Decrease Reactive Astrogliosis in the Injured Brain: Effects of Aging and Prolonged Depletion of Ovarian Hormones
Endocrinology 2009 150: 5010-5015 , doi:10.1210/en.2009-0352 [Abstract] [Full Text] [PDF]  
Estradiol and estrogenic compounds used in clinics reduce the activation of astroglial cells after brain injury in young, middle-aged, and aged animals as well as in aged animals after a long-term deprivation of ovarian hormones.

J. Roa, D. Garcia-Galiano, L. Varela, M. A. Sánchez-Garrido, R. Pineda, J. M. Castellano, F. Ruiz-Pino, M. Romero, E. Aguilar, M. López, F. Gaytan, C. Diéguez, L. Pinilla, and M. Tena-Sempere

The Mammalian Target of Rapamycin as Novel Central Regulator of Puberty Onset via Modulation of Hypothalamic Kiss1 System
Endocrinology 2009 150: 5016-5026 , doi:10.1210/en.2009-0096 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Central mTOR signaling is involved in the control of puberty onset and gonadotropin secretion via regulation of Kiss1, a phenomenon that may contribute to the metabolic regulation of gonadal activation and function.

RENAL-CARDIAC-VASCULAR:

Jiaur R. Gayen, Yusu Gu, Daniel T. O'Connor, and Sushil K. Mahata

Global Disturbances in Autonomic Function Yield Cardiovascular Instability and Hypertension in the Chromogranin A Null Mouse
Endocrinology 2009 150: 5027-5035 , doi:10.1210/en.2009-0429 [Abstract] [Full Text] [PDF]  
Ablation of Chga gene expression results in global disturbances in sympathetic and parasympathetic autonomic function, that can be abrogated (or "rescued") by replacement of catestatin.

REPRODUCTION-DEVELOPMENT:

Lynn Roy, Claudia A. McDonald, Chao Jiang, Dulce Maroni, Anthony J. Zeleznik, Todd A. Wyatt, Xiaoying Hou, and John S. Davis

Convergence of 3',5'-Cyclic Adenosine 5'-Monophosphate/Protein Kinase A and Glycogen Synthase Kinase-3β/β-Catenin Signaling in Corpus Luteum Progesterone Synthesis
Endocrinology 2009 150: 5036-5045 , doi:10.1210/en.2009-0771 [Abstract] [Full Text] [PDF]  
Luteinizing hormone stimulates cAMP/PKA regulation of GSK3β/β-catenin signaling that contributes to progesterone secretion.

Bárbara Loureiro, Luciano Bonilla, Jeremy Block, Justin M. Fear, Aline Q. S. Bonilla, and Peter J. Hansen

Colony-Stimulating Factor 2 (CSF-2) Improves Development and Posttransfer Survival of Bovine Embryos Produced in Vitro
Endocrinology 2009 150: 5046-5054 , doi:10.1210/en.2009-0481 [Abstract] [Full Text] [PDF]  
Exposure of preimplantation bovine embryos to CSF-2 improves development and enhances embryo competence for post-transfer survival.

Amanda J. Drake, Sander van den Driesche, Hayley M. Scott, Gary R. Hutchison, Jonathan R. Seckl, and Richard M. Sharpe

Glucocorticoids Amplify Dibutyl Phthalate-Induced Disruption of Testosterone Production and Male Reproductive Development
Endocrinology 2009 150: 5055-5064 , doi:10.1210/en.2009-0700 [Abstract] [Full Text] [PDF]  
Combinations of insults in fetal life may act together to increase the risk of common male reproductive abnormalities.

Xiaofei Sun, Lindsey Jackson, Sudhansu K. Dey, and Takiko Daikoku

In Pursuit of Leucine-Rich Repeat-Containing G Protein-Coupled Receptor-5 Regulation and Function in the Uterus
Endocrinology 2009 150: 5065-5073 , doi:10.1210/en.2009-0690 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Lgr5 is uniquely and dynamically expressed in the mouse uterus under changing conditions, suggesting its important role in uterine biology.

Liza O'Donnell, Kyriakos Pratis, Andrea Wagenfeld, Ulrich Gottwald, Jörg Müller, Gabriele Leder, Robert I. McLachlan, and Peter G. Stanton

Transcriptional Profiling of the Hormone-Responsive Stages of Spermatogenesis Reveals Cell-, Stage-, and Hormone-Specific Events
Endocrinology 2009 150: 5074-5084 , doi:10.1210/en.2009-0755 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Microarray analysis identifies cohorts of genes whose expression is up or down-regulated in Sertoli cells and specific classes of germ cells during combined androgen and FSH suppression.

So-Youn Kim, Jeffrey Weiss, Minghan Tong, Monica M. Laronda, Eun-Jig Lee, and J. Larry Jameson

Foxl2, a Forkhead Transcription Factor, Modulates Nonclassical Activity of the Estrogen Receptor-
Endocrinology 2009 150: 5085-5093 , doi:10.1210/en.2009-0313 [Abstract] [Full Text] [PDF]  
The forkhead transcription factor, Foxl2, which is required for ovary development, interacts with estrogen receptor (ER), and suppresses ER signaling through tethered transcription pathways.

Héloïse P. Gaide Chevronnay, Christine Galant, Pascale Lemoine, Pierre J. Courtoy, Etienne Marbaix, and Patrick Henriet

Spatiotemporal Coupling of Focal Extracellular Matrix Degradation and Reconstruction in the Menstrual Human Endometrium
Endocrinology 2009 150: 5094-5105 , doi:10.1210/en.2009-0750 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Microarray comparison of transcriptomes from degraded and preserved areas within the menstruating endometrium, after microdissection to separate tissue compartments, shows that endometrial reconstruction during menstruation involves cells from lysed areas of the superficial stroma.

TECHNICAL COMMUNICATIONS:

Yasushi Hojo, Shimpei Higo, Hirotaka Ishii, Yuuki Ooishi, Hideo Mukai, Gen Murakami, Toshihiro Kominami, Tetsuya Kimoto, Seijiro Honma, Donald Poirier, and Suguru Kawato

Comparison between Hippocampus-Synthesized and Circulation-Derived Sex Steroids in the Hippocampus
Endocrinology 2009 150: 5106-5112 , doi:10.1210/en.2009-0305 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Improved mass-spectrometric analysis revealed that hippocampal estradiol is mainly synthesized from hippocampus-derived testosterone, and not significantly from circulating testosterone.

Andreas Stengel, David Keire, Miriam Goebel, Lena Evilevitch, Brian Wiggins, Yvette Taché, and Joseph R. Reeve, Jr.

The RAPID Method for Blood Processing Yields New Insight in Plasma Concentrations and Molecular Forms of Circulating Gut Peptides
Endocrinology 2009 150: 5113-5118 , doi:10.1210/en.2009-0697 [Abstract] [Full Text] [PDF] [Supplemental Data]  
The RAPID method allows correct assessment of circulating peptide levels and more importantly their correct bioactive molecular forms.

Sheri A. Berenbaum, Kristina Korman Bryk, Nicole Nowak, Charmian A. Quigley, and Scott Moffat

Fingers as a Marker of Prenatal Androgen Exposure
Endocrinology 2009 150: 5119-5124 , doi:10.1210/en.2009-0774 [Abstract] [Full Text] [PDF]  
Data from individuals with complete androgen insensitivity show that digit ratio (2D:4D) is not a good marker of individual differences in prenatal androgen exposure.

THYROID-TRH-TSH:

Dan Gratschev, Christoffer Löf, Jari Heikkilä, Anders Björkbom, Pramod Sukumaran, Ari Hinkkanen, J. Peter Slotte, and Kid Törnquist

Sphingosine Kinase as a Regulator of Calcium Entry through Autocrine Sphingosine 1-Phosphate Signaling in Thyroid FRTL-5 Cells
Endocrinology 2009 150: 5125-5134 , doi:10.1210/en.2009-0288 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Lipid sphingosine 1-phosphate enhances calcium entry in thyroid cells by an autocrine mechanism.

Ichiro Horie, Norio Abiru, Yuji Nagayama, Genpei Kuriya, Ohki Saitoh, Tatsuki Ichikawa, Yoichiro Iwakura, and Katsumi Eguchi

T Helper Type 17 Immune Response Plays an Indispensable Role for Development of Iodine-Induced Autoimmune Thyroiditis in Nonobese Diabetic-H2^h4 Mice
Endocrinology 2009 150: 5135-5142 , doi:10.1210/en.2009-0434 [Abstract] [Full Text] [PDF]  
A newly identified T helper type 17 immune response plays a significant role in development of iodine-induced autoimmune thyroiditis in nonobese diabetic-H2^h4 mice.

Aurora Sánchez-Pacheco, Olaia Martínez-Iglesias, Marinela Méndez-Pertuz, and Ana Aranda

Residues K128, 132, and 134 in the Thyroid Hormone Receptor- Are Essential for Receptor Acetylation and Activity
Endocrinology 2009 150: 5143-5152 , doi:10.1210/en.2009-0117 [Abstract] [Full Text] [PDF]  
TR is acetylated by T3 on three lysine residues in the CTE region which also plays a key role on ligand affinity, transactivation, transrepression, and anti-transforming properties of TR.

Daniel E. Westholm, David R. Salo, Kevin J. Viken, Jon N. Rumbley, and Grant W. Anderson

The Blood-Brain Barrier Thyroxine Transporter Organic Anion-Transporting Polypeptide 1c1 Displays Atypical Transport Kinetics
Endocrinology 2009 150: 5153-5162 , doi:10.1210/en.2009-0769 [Abstract] [Full Text] [PDF]  
Oatp1c1 carries multiple thyroxine and estradiol-17β-glucuronide binding sites and exhibits biphasic transport kinetics.

W. Edward Visser, Nancy J. Philp, Thamar B. van Dijk, Wim Klootwijk, Edith C. H. Friesema, Jurgen Jansen, Philip W. Beesley, Alexandra G. Ianculescu, and Theo J. Visser

Evidence for a Homodimeric Structure of Human Monocarboxylate Transporter 8
Endocrinology 2009 150: 5163-5170 , doi:10.1210/en.2009-0699 [Abstract] [Full Text] [PDF] [Supplemental Data]  
Monocarboxyate transporter 8 (MCT8) is an important thyroid hormone transporter. This study presents basic characteristics of the MCT8 structure.

Goele Aerts, Rafael Arrojo e Drigo, Stijn L. J. Van Herck, Eva Sammels, Delphine Mirebeau-Prunier, Balázs Gereben, Anikó Zeöld, John W. Harney, Stephen A. Huang, Michelle A. Mulcahey, Serge Van der Geyten, Gert Van den Bergh, Lut Arckens, Veerle M. Darras, and Ann Marie Zavacki

Knockdown of the Type 3 Iodothyronine Deiodinase (D3) Interacting Protein Peroxiredoxin 3 Decreases D3-Mediated Deiodination in Intact Cells
Endocrinology 2009 150: 5171-5180 , doi:10.1210/en.2009-0702 [Abstract] [Full Text] [PDF]  
Prx3 knock down decreases D3 activity in intact cells.

Ericka Diallo-Krou, Jingcheng Yu, Lesley A. Colby, Ken Inoki, John E. Wilkinson, Dafydd G. Thomas, Thomas J. Giordano, and Ronald J. Koenig

Paired Box Gene 8-Peroxisome Proliferator-Activated Receptor- Fusion Protein and Loss of Phosphatase and Tensin Homolog Synergistically Cause Thyroid Hyperplasia in Transgenic Mice
Endocrinology 2009 150: 5181-5190 , doi:10.1210/en.2009-0701 [Abstract] [Full Text] [PDF]  
PAX8-PPAR fusion protein, which is expressed as a consequence of a t(2;3)(q13;p25) chromosomal translocation in follicular thyroid neoplasms, causes hyperplasia and increased AKT signaling in the thyroids of transgenic mice.

TRANSLATIONAL HIGHLIGHTS FROM JCEM:

Elizabeth A. Lawson, Daniel Donoho, Karen K. Miller, Madhusmita Misra, Erinne Meenaghan, Janet Lydecker, Tamara Wexler, David B. Herzog, and Anne Klibanski

Hypercortisolemia Is Associated with Severity of Bone Loss and Depression in Hypothalamic Amenorrhea and Anorexia Nervosa
Endocrinology 2009 150: 5191-5192 [Full Text] [PDF]  

Beverley M. Shields, Rachel M. Freathy, Bridget A. Knight, Anita Hill, Michael N. Weedon, Timothy M. Frayling, Andrew T. Hattersley, and Bijay Vaidya

Phosphodiesterase 8B Gene Polymorphism Is Associated with Subclinical Hypothyroidism in Pregnancy
Endocrinology 2009 150: 5191-a [Full Text] [PDF]  

Ayman M. Arafat, Martin O. Weickert, Jan Frystyk, Joachim Spranger, Christof Schöfl, Matthias Möhlig, and Andreas F.H. Pfeiffer

The Role of Insulin-Like Growth Factor (IGF) Binding Protein-2 in the Insulin-Mediated Decrease in IGF-I Bioactivity
Endocrinology 2009 150: 5192 [Full Text] [PDF]  

Rita Rastogi Kalyani, Manuel Franco, Adrian S. Dobs, Pamela Ouyang, Dhananjay Vaidya, Alain Bertoni, Susan M. Gapstur, and Sherita Hill Golden

The Association of Endogenous Sex Hormones, Adiposity, and Insulin Resistance with Incident Diabetes in Postmenopausal Women
Endocrinology 2009 150: 5192-a [Full Text] [PDF]  

ERRATUM:

Erratum
Endocrinology 2009 150: 5193 [Full Text] [PDF]  

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